The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

Embodiments disclosed herein are directed to a drainage system for draining a fluid from a patient where the system includes a drainage tube that provides fluid communication between a catheter and a collection container. The drainage tube includes a port and a balloon attached to an interior of the drainage tube, where the balloon is configured to receive air from a needle that has pierced the port and occlude a lumen of the drainage tube. When in an inflated state, the balloon occludes the lumen of the drainage tube thereby breaking the fluid communication between the catheter and the collection container and preventing the output airflow device from drawing airflow out of the catheter. The balloon may be attached to the interior of the drainage tube by surrounding an interior side of the port.

A method for maintaining a balloon of a balloon catheter at a prescribed pressure of between about 0.2 psi and 1 psi comprises the step of: generating a vacuum within a reservoir defined in a burette that is part of a fluid management system that is configured to controllably inflating and deflating the balloon by circulating balloon fill media along a fluid circuit, wherein generating the vacuum results in formation of a pressure differential along the fluid circuit, thereby allowing the balloon to be maintained at the prescribed pressure between about 0.2 psi and about 1 psi.

An inhalation-synchronized fluid product dispenser device having a body (10) provided with a mouthpiece (400), a product reservoir (100) containing fluid product, and a dispenser mechanism (200). The device has a blocking mechanism (500; 600) for the dispenser mechanism and an inhalation-controlled trigger system having an inhalation-sensitive member (60) deformable and/or movable by inhalation, the inhalation-sensitive member co-operating with the blocking mechanism so that when deformed and/or moved, it enables the dispenser mechanism to be actuated. The device has a protective element (1) the trigger system, the protective element disposed between the mouthpiece and the inhalation-sensitive member and made of a porous material that allows air to pass through it but blocks the passage of water, dust and foreign bodies.

The cover for a drug delivery tube device according to a disclosed embodiment is configured to define an insertion space having an opening formed on a lower side thereof so that the drug delivery tube device having a capillary flow path configured to allow a drug solution to flow therethrough is capable of being inserted into the opening. The cover includes a cover body extending along a circumference of the insertion space around a center axis perpendicular to an upper-lower direction.

The invention relates to a device for the dynamically adapting sealing of an organ or a body cavity, e.g. the windpipe (trachea) of an intubated and ventilated patient, wherein the sealing balloon element is produced via particularly rapid shifting of filling medium from an extracorporeal reservoir or an extracorporeal source to the sealing balloon, and wherein, in the dynamic sealing of the trachea according to the example case, a balloon-type foil body preferably formed with residual material in the diameter, i.e. exceeding the tracheal diameter, is in contact with the inner wall of the trachea in a sealing manner and with a pressure that is as constant as possible, wherein fluctuations in the balloon volume, caused by fluctuations in the intrathoracic pressure relating to the mechanics of breathing, are compensated as quickly as possible by supplying volume from an extracorporeal reservoir or an extracorporeal source, and the tracheal secretion sealing of the balloon is thereby kept continuous. This is both made possible by a sufficiently high-volume supply of the balloon filling medium to the cuff, and also prevents steps, gaps or ridges in the supply system, whereby volume flow directed towards the balloon can be minimised, which is crucial for a rapid-as-possible stabilising of the filling volume in the balloon, in particular with small pressure differences between 15 and 30 mbar that are driving the volume flow.

Disclosed herein are several embodiments of a wound treatment apparatus employing a wound dressing for negative pressure wound therapy and methods of using the same. Some embodiments are directed to improved wound dressing to be applied to a wound site, for example a wound dressing including a three-dimensional filter element, and methods of using the same.

A nasal droplet delivery device and related methods for delivering precise and repeatable dosages to a subject via the nasal passageways and sinus cavities.

A system for delivery of gas to a tissue, comprises: a first container containing the gas, an applicator having a distal end arranged to deliver the gas to the tissue, a second container containing a purging gas; and a flow control system for controlling flow of gas. The system also comprises a three-port valve having a first port for receiving the gas from the first container, a second port for receiving the purging gas from the second container, and a third port in fluid communication with the applicator. The valve is switchable between a first state at which the first port fluidly connects to the third port, and a second state at which the second port fluidly connects to the third port.

A blood processing apparatus includes an optional heat exchanger and a gas exchanger disposed within a housing. In some instances, the gas exchanger can include a screen filter spirally wound into the gas exchanger such that blood passing through the gas exchanger passes through the screen filter and is filtered by the spirally wound screen filter a plurality of times.