A vaccination device can be used to vaccinate day-old chicks. To vaccinate the day-old chicks safely while ensuring vaccination efficacy, the vaccination device can include a vaccination needle configured to extend from the vaccination device at a vaccination delivery location and an action plate. The action plate can be coupled to the vaccination device such that the action plate is positioned next to the vaccination delivery location. The action plate can include an action button, wherein the action button is configured to receive a day-old chick presented to the action plate in a predetermined loading position, receive a press of the action button, and in response to pressing the action button, cause the vaccination needle to extend from the vaccination device at the vaccination delivery location to deliver a subcutaneous injection to the day-old chick.

Hemodialysis systems are described. A hemodialysis system may include a dialysate flow path through which dialysate is passed from a dialysate reservoir, which includes a valved vent to atmosphere, to an ultrafilter. The dialysate flow path includes a pneumatically actuated diaphragm-based dialysate pump for pumping fluid from the dialysate reservoir to the ultrafilter. The hemodialysis system may include a controller for controlling pneumatic actuation pressure delivered to the dialysate pump and at least one valve connecting the dialysate reservoir vent to the atmosphere. The hemodialysis system may be configured to actuate the dialysate pump and the at least one valve to introduce air into the dialysate flow path and expel liquid from the dialysate flow path to a drain.

Embodiments described herein describe a drug delivery device and a method of use thereof. The device includes a medicament container, a compressed gas container, an outlet, and a double-sided needle located within the housing. When a user presses an actuation button, the compressed air container is moved towards the medicament container and towards a proximal end of the double-sided needle. The double-sided needle pierces both the compressed gas container and the medicament container, opening fluid flow communication between the two containers, and causing medicament to be expelled out of the medicament container.

An infusion device for dispensing fluid at a predetermined flow rate includes an elastic bladder, a pressure regulator, and a flow restrictor. The elastic bladder includes a bladder volume portion and a bladder outlet, and the elastic bladder stores fluid in the bladder volume portion and dispenses fluid through the outlet at a bladder pressure. The pressure regulator is in fluid communication with the outlet of the elastic bladder. The pressure regulator includes a fluid inlet and a fluid outlet. The fluid inlet is coupled to the bladder outlet to receive fluid from the bladder. The flow restrictor is in fluid communication with the fluid outlet. The flow restrictor and the pressure regulator cooperate to discharge fluid from the flow restrictor at a predetermined flow rate.

Apparatus for transdermal delivery of a powdered agent to a patient, the apparatus comprising a fluid source comprising a fluid; a nozzle extending distally from the fluid source, the nozzle comprising a proximal end, a distal end and a lumen extending from the proximal end to the distal end; a blister containing a powdered agent disposed within the lumen of the nozzle; and an actuation element for releasing the fluid from the fluid source, wherein the actuation element causes the released fluid to be propelled through the blister with sufficient pressure to entrain the powdered agent into the released fluid and move the entrained powdered agent through the lumen of the nozzle and out the distal end of the nozzle.

An automatic medicine exchange and atomization device includes a breathing tube, a main control module, an atomization module and a plurality of medicine solution containers. The breathing tube communicates with a patient's respiratory tract. At least one medicine solution container, each containing a corresponding medicinal liquid, communicates with the breathing tube, and is connected to the atomization module. The atomization module is electrically connected to the main control module, which controls the atomization module to atomize a solution in a selected one of the container, so that the atomized medicine solution enters the breathing tube. As the main control module controls, according to the needs of different experiments in different stages, the atomization module to atomize the medicine solution in the specific medicine solution container, thus requiring no manual replacement, and being convenient and fast.

A medicament delivery device for delivering a liquid medicament comprising: a rigid casing containing a deformable medicament container, the deformable medicament container arranged to contain the liquid medicament; a pressurized gas cartridge connected to the rigid casing via a gas valve; wherein the gas valve is releasable to allow gas flow into the rigid casing to cause an increase in gas pressure in the rigid casing so as to compress the deformable medicament container to displace the liquid medicament.

A device and a method for adjustable quantitative injection of high-pressure gas are provided, wherein the gas may have a pressure of 5 MPa or more than 5 MPa. The gas may be directly communicated with a gas tank in the mechanism or an external gas source, flows through corresponding valves, and is charged into a predetermined or adjustable reservoir. Alternatively, the valve may be time-controllable, and does not need the reservoir. The gas is ejected through a nozzle selected based on depth or range of injection, wherein a one-way valve is disposed between the nozzle and the body to prevent contamination due to backflow. The manipulator can exert an appropriate force onto a target portion of a human for gas injection, and when the injection is done, a biasing member can automatically return the mechanism to its original state, ready for the next injection.

Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.

A self-inflating cuff and methods of using the self-inflating cuff are provided. The self-inflating cuff includes first and second compartments formed within the self-inflating cuff and housing respective substances. The first and second compartments are configured to rupture in response to the force applied to an exterior surface of the self-inflating cuff, which causes the respective substances to combine to initiate a chemical reaction to produce a reactionary force on an interior surface of the self-inflating cuff that causes the self-inflating cuff to expand. The self-inflating cuff is further configured to expand such that a first opening at a first end of the self-inflating cuff and a second opening at a second end opposite the first end of the self-inflating cuff enlarge enough to receive a container through the first opening and a tubing of the container through the second opening.