An electronic smoking article includes a liquid supply including liquid material, a heater operable to heat the liquid material to a temperature sufficient to vaporize the liquid material and form an aerosol, a wick in communication with the liquid material and in communication with the heater such that the wick delivers the liquid material to the heater, at least one air inlet operable to deliver air to a central air passage upstream of the heater, and a mouth end insert having at least two diverging outlets.

An optical circuit detects PPG signals reflected from skin tissue at one or more different wavelengths. A processing circuit integrated in the biosensor or in communication with the biosensor processes the PPG signals to obtain a period of vasodilation, a level of vasodilation and rate of change of the level of vasodilation. The processing circuit compares the level of vasodilation to a normal range and determines an arterial stiffness index using the comparison and the rate of change of the level of vasodilation.

An electronic smoking article includes an outer tube extending in a longitudinal direction, an inner tube within the outer tube and including a pair of opposing slots, a liquid supply comprising a liquid material, a coil heater, a wick and a mouth end insert. The coil heater is located in the inner tube. The coil heater is formed of an iron-free, nickel-chromium alloy and has substantially uniformly spaced windings. The wick is surrounded by the coil heater such that the wick delivers liquid material to the coil heater and the coil heater heats the liquid material to a temperature sufficient to vaporize the liquid material and form an aerosol in the inner tube.

An apparatus for generating dialysate for dialysis comprising a dialysate outlet and a dialysate inlet and dialysate purifying means, wherein the purifying means comprise a cryopurifier for generating pure water, wherein the inlet of the cryopurifier is connected to the dialysate outlet and the outlet of the cryopurifier is connected to the dialysate inlet; and a method for reclaiming of fresh dialysate from ultrafiltrate and wasted dialysate extracted from a dialysis patient, comprising the following steps: preparing an ice slurry from the dialysate, wherein the ice slurry contains ice crystals and a liquid containing solutes; and separating the ice crystals from the liquid containing the solutes.

A sleep enhancement device for toddlers and young children, including: a containment assembly and an electronics assembly, wherein both assemblies cooperatively create the psychological appearance that the device is at least one of catching and destroying monsters and/or bad dreams, and provides a soothing, relaxing, deep, and/or healthy sleep.

A head-mounted respiratory assistance apparatus configured to provide a respiratory gases stream to a user. The head-mounted respiratory assistance has a main body securable to the head of a user and a blower unit that is operable to generate a pressurised gases stream from a supply of gases from the surrounding atmosphere. A patient interface is provided on the main body that has a gases inlet which is fluidly connected to the blower unit and which is configured to deliver the pressurised gases to the user's nose and/or mouth.

This invention relates to an ingestible drug delivery device configured for wireless communication with other ingestible drug delivery devices.

A biosensor includes a photoplethysmography (PPG) circuit configured to obtain spectral responses at one or more wavelengths from skin tissue of the patient over a predetermined time period. The biosensor monitors the color of the blood to detect a change in the baseline color of blood flow over the predetermined time period. The biosensor may determine a level of red blood cells or white blood cells or a risk of an infection using the change in the baseline color of blood flow. The biosensor may also detect other parameters to detect an infection or identify a type of infection including liver enzyme levels, nitric oxide levels, heart rate or vasodilation in the underlying tissue.

A system to provide active agent (e.g., scent molecules) includes a delivery system that may include a reservoir, an actuator (e.g., nebulizer), and a fluidly communicative scent path through which a vapor or aerosol may be supplied or dispensed, the vapor or aerosol comprising readily-soluble droplets having a median size range of approximately 2 microns to approximately 50, 20, or 10 microns for introduction to an animal via a retro-nasal route. The vapor or aerosol may be dispensed below a top of the vessel, in a direction that at least initially retains the vapor or aerosol in the vessel. The system may include a base to support or secure the vessel, a cover to close the vessel, and, or a conduit or straw to sip from the vessel. The system can include switches or sensors to provide signals to control operation of the actuator, for instance, based on position, orientation, or direct or indirect user input. The system takes the form of conduit, e.g., straw or stirrer.

This invention relates to an ingestible drug delivery device configured for wireless communication with other ingestible drug delivery devices.