Embodiments relate to an intranasal drug delivery device, system, and process. The drug delivery device can have a compliant/flexible soft nib. The drug delivery device can have an actuator and shot chamber. The drug delivery device can have a non-air interface mechanically pressurized fluid reservoir. The drug delivery device can have a facial or device recognition application to prevent intentional or unintentional misuse.

A patient interface for sealed delivery of a flow of air to ameliorate sleep disordered breathing may include: a seal-forming structure to form a pneumatic seal with the entrance to the patient's airways; a positioning and stabilising structure to maintain the seal-forming structure in sealing contact with an area surrounding the entrance to the patient's airways; a plenum chamber pressurised at a pressure above ambient pressure in use; a connection port for the delivery of the flow of breathable gas into the patient interface; and a device positioned within a breathing chamber defined, at least in part, by the seal-forming structure and the plenum chamber, wherein the device divides the breathing chamber into a posterior chamber and an anterior chamber, and wherein the device comprises a plurality of apertures such that turbulence of the air in the posterior chamber is less than turbulence in the air in the anterior chamber.

A respiratory therapy system can have a flow generator adapted to provide gases to a patient. A gas passageway can be located in-line with the flow generator. The gas passageway can have a first portion adapted to receive a first gas and a second portion adapted to receive a second gas. The gas passageway can have a static mixer downstream of the first and second portions.

Drug delivery system including: a reservoir having a meander shape or spiral shape, the reservoir including an inlet and a filter; a capacitance measurement device configured to determine a parameter of the reservoir; and a micropump configured to deliver a fluid from the reservoir to an outlet.

The present invention relates to a device for a respiration arrangement. The device comprises a conduit having a first opening connectable to an air/gas source such as a resuscitation bag, and a second opening connectable to a face mask, such that a fluid pathway along a longitudinal direction of the conduit is established from the first opening to the second opening. The device further comprises a flow constriction, arranged in the conduit which upon fluid flow through the conduit results in a pressure difference over the flow constriction, the flow constriction at least partly comprising a laminar flow section, wherein the device further comprises at least one pressure connecting port arranged in pressurized communication with fluid between the flow constriction and the first opening, and wherein the pressure connecting port is arranged in the longitudinal direction of the conduit.

The invention relates to a device for the dynamically adapting sealing of an organ or a body cavity, e.g. the windpipe (trachea) of an intubated and ventilated patient, wherein the sealing balloon element is produced via particularly rapid shifting of filling medium from an extracorporeal reservoir or an extracorporeal source to the sealing balloon, and wherein, in the dynamic sealing of the trachea according to the example case, a balloon-type foil body preferably formed with residual material in the diameter, i.e. exceeding the tracheal diameter, is in contact with the inner wall of the trachea in a sealing manner and with a pressure that is as constant as possible, wherein fluctuations in the balloon volume, caused by fluctuations in the intrathoracic pressure relating to the mechanics of breathing, are compensated as quickly as possible by supplying volume from an extracorporeal reservoir or an extracorporeal source, and the tracheal secretion sealing of the balloon is thereby kept continuous. This is both made possible by a sufficiently high-volume supply of the balloon filling medium to the cuff, and also prevents steps, gaps or ridges in the supply system, whereby volume flow directed towards the balloon can be minimised, which is crucial for a rapid-as-possible stabilising of the filling volume in the balloon, in particular with small pressure differences between 15 and 30 mbar that are driving the volume flow.

A dry-powder inhaler may include a first casing portion, a second casing portion, and a hinge arrangement connecting the first casing portion and the second casing portion. The dry-powder inhaler may be assembled by folding the first casing portion and the second casing portion together. The first casing portion may include a cavity for receiving a dose blister foil, said cavity being adapted to contain a dry-powder medicament. The first casing portion and the second casing portion when folded together may be adapted to form an inlet for allowing a lidding foil extending out there from and an outlet for providing the medicament.

A nasal droplet delivery device and related methods for delivering precise and repeatable dosages to a subject via the nasal passageways and sinus cavities.

Systems and devices are provided for heating an infusible liquid. The inline heater includes a fluid flow channel defined by a conduit for flowing an infusible liquid through a first portion of the conduit having a first cross-sectional dimension to a second portion of the conduit having a smaller second cross-sectional dimension. A nozzle is disposed in the first portion of the conduit. A heating element in thermal communication with an outer surface of the second portion of the conduit conducts heat through the conduit into the infusible liquid. The nozzle is positioned to spray the infusible liquid about a circumference of an inner wall of the second portion of the conduit to provide increased heat transfer from the heating element to the infusible liquid. The inline heater may be formed as a cassette for use in a dialysis machine.

Flow capture device and method for removing cells from blood The current invention discloses a blood treating and/or purifying device for removing circulating pathogens, preferably pathogenic cells, more preferably circulating tumor cells from the blood of a patient, a method of producing such a device and method to treat cancer and other diseases caused by virus infection, bacterial infection and parasites infection as well as autoimmune disorders. The described method is an extracorporeal medical therapy, thus can be done also in a hemodialysis system. The current invention also describes a device and an in-situ production method of preparing the device to remove CTC and other pathogens i.e. virus, bacteria or parasites from the bloodstream.