An inhaler article (150) includes a body extending along a longitudinal axis from a mouthpiece end (154) to a distal end (156), a capsule cavity (155) defined within the body and a capsule disposed within the capsule cavity. The capsule cavity is bounded downstream by a filter element and bounded upstream and distally by a deformable element (158) the deformable element deforms to expose an open distal end and allow the inhaler article to receive swirling or rotational inhalation airflow during consumption.

A dry powder inhaler for a capsule containing dry powder, the inhaler comprising a housing having a capsule receptacle, two actuator buttons arranged on opposing sides of the housing and two perforation needles, each needle being fixedly connected to an actuator button and movable relative to the housing towards each other from a normal position to a perforation position along an actuation direction to perforate a capsule arranged in the capsule receptacle, wherein a first end of each actuator button is connected to the housing at a lower portion of the housing and in that a second free end of each actuator button is movable into the perforation position such that the perforation needle is moved along a circular line.

An inhaler article (110) comprises a body (112) extending along a longitudinal axis (A) from a mouthpiece end (113) to a distal end (114), a capsule cavity (116) defined within the body, and a distal end element (118) disposed at the distal end and extending to the capsule cavity. The distal end element comprises an element distal end (120), an element inner end (122), a solid core portion (124), and at least two grooves (126). The solid core portion extends from the element distal end to the element inner end. The at least two grooves are helical grooves that rotate about solid core portion along the longitudinal axis from the element distal end to the element inner end. The at least two helical grooves extend along an outer surface (128) of the distal end element.

An inhaler article (150) includes a body (151) extending along a longitudinal axis of the inhaler article from a mouthpiece end (154) to a distal end (156), a capsule cavity (155) and a capsule (160) retained within the capsule cavity. The capsule cavity is defined within the body and bounded downstream by a filter element (157) and bounded upstream by a tubular element (153) defining a central passage (152) in fluid communication with the capsule cavity. The central passage forms an air inlet aperture extending along the longitudinal axis of the inhaler article from the distal end of the body towards the capsule cavity, wherein the tubular element has a central passage inner diameter in a range from about 50% to about 90% of an inner diameter of the capsule cavity. The inhaler article is configured to receive a swirling inhalation airflow into the central passage.

An inhaler article includes a body extending along a longitudinal axis from a mouthpiece end to a distal end, a capsule cavity defined within the body and a tubular element extending from the distal end towards the capsule cavity. The tubular element defines a central passage extending from the distal end towards the capsule cavity. The tubular element includes at least one air inlet allowing air to enter into the central passage. The at least one air inlet extends in a direction that is tangential to the central passage.

A holder for an inhaler article includes a housing comprising a housing cavity for receiving an inhaler article a sleeve configured to retain an inhaler article within the housing cavity. The sleeve includes a sleeve cavity and is movable within the housing cavity along a longitudinal axis of the housing. The sleeve includes a first open end and a second opposing end. The first open end is configured to receive an inhaler article and the second opposing end of the sleeve is configured to allow air to enter the sleeve cavity. The second opposing end of the sleeve is configured to induce a swirl on the air entering the sleeve cavity.

The present invention provides a particulate delivery device with an automatic activation mechanism that pierces or cuts a composition capsule when a cap is removed. The cap cannot be replaced once the device is activated for use. The device allows for gas flow through the device from a gas inlet to a gas outlet through a composition receptacle and dispersion chamber to deliver particulate to the airway of a subject.

A syringe-shaped spraying device includes: a syringe-shaped spraying device main body including a barrel that stores a liquid medicine, a plunger having a front end inserted in the barrel with a gasket being attached to the front end, and a nozzle that is provided with a spraying hole for spraying the liquid medicine and that is connected to a front end of the barrel; a vial adapter having a transfer needle to pierce a vial that stores a liquid medicine so as to suction the liquid medicine; and a connection adapter that is attached to the syringe-shaped spraying device main body and that connects the vial adapter to the syringe-shaped spraying device main body.

A dry powder inhaler with a blister folding device can include a housing to receive a single blister containing a dose of medicament for inhalation by a user, and a mouthpiece through which a dose of medicament is inhaled by a user and a blister opening device. The blister opening device can include a blister support element for supporting a blister containing a dose of medicament for inhalation by a user, and a blister folding element co-operable with the blister support element. The blister folding element and the blister support element can be movable relative to each other between a first position, for insertion of the blister into or onto the blister support element, and a second, burst, position in which the blister folding element has co-operated with the blister support element.

A dilution spacer for a metered-dose inhaler comprises an enclosure defining a dilution chamber. An ambient air inlet and an outlet are in fluid communication with the dilution chamber. The ambient air inlet is positioned opposite the outlet whereby suction through the outlet from outside the enclosure draws ambient air into the enclosure through the ambient air inlet to generate an airflow path from the ambient air inlet through the dilution chamber and out of the outlet. The dilution spacer may include an actuator inlet configured to securely releasably interengage a metered-dose inhaler actuator mouthpiece, or may include a receptacle having an actuator nozzle and configured to receive a metered-dose inhaler canister, A metered-dose inhaler plume entering the dilution chamber intersects the airflow path thereto and airflow along the airflow path entrains and redirects at least a portion of the metered-dose inhaler plume toward the outlet.