A nebulizer assembly for a respiratory device is provided having a housing defining a chamber. The housing also has a nebulizer port configured to receive a nebulizer to discharge atomized medication into the chamber. An outlet of a handle is coupled to the inlet of the housing. A hose is coupled to an inlet of the handle. A patient interface is coupled to the outlet of the housing. Air flows from the hose to the patient interface via the handle and the housing. The air mixes with the atomized medication within the chamber.

A system for dispensing a biocompatible reactive formulation includes a first chamber containing a first fluid having a first reactive component, a second chamber containing a second fluid having a second reactive component, and a third chamber containing a third fluid. A spray tip assembly is configured for spraying a final mixture of the first, second and third fluids. The spray tip assembly has a spray tip housing, a mixing element disposed within the spray tip housing, a mixing chamber located between the mixing element and an inner surface of the spray tip housing. The mixing element has a proximal end adjacent the proximal end of the spray tip housing and a distal end adjacent the distal end of the spray tip housing, a third fluid inlet opening at the proximal end of the mixing element, and one or more third fluid exit openings formed in the outer surface of the mixing element that are in fluid communication with the third fluid inlet opening and that extend laterally to the outer surface of the mixing element for being in fluid communication with the mixing chamber. A fluid connector is secured to the proximal end of the spray tip housing and opposes the proximal end of the mixing element. The fluid connector has first and second fluid channels in fluid communication with the mixing chamber, and a third fluid channel in fluid communication with the third fluid inlet opening of the mixing element. A pump assembly is coupled with the first, second and third chambers for simultaneously forcing the first, second and third fluids to flow through the first, second and third fluid channels of the fluid connector and into the proximal end of the spray tip housing.

Described herein are devices, systems, and methods for generating a variable liquid vacuum with an accompanying stable gas flow rate. In particular, when a suction device suctions a liquid and gas mixture it is advantageous to provide a variable vacuum or vacuum to apply to the liquid component while the flow rate of the gas stays constant or essentially constant.

A delivery device for use in administering a dry powder to a biological subject's airway is provided. The device comprises (a) a housing having an inlet in fluid communication with an outlet for delivering a flow of gas to the subject's airway; and (b) one or more cantilever structures located within the housing. Vibration of the one or more cantilever structures facilitates entry of the dry powder into the flow of gas, such that the dry powder can be delivered by the flow of gas through the outlet to the subject's airway. Also provided is a container for releasably storing a particulate composition, the container comprising a shell sealed by a seal in which the particulate composition is stored, wherein a puncturing device for rupturing the seal to release the particulate composition is housed within the shell. Further provided are associated methods for administering dry powder using the delivery device and/or container.

Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose.

Systems and methods for humidifying ventilator delivered breathing gases are disclosed. These systems and methods utilize a hollow cone atomizer (e.g., a pressure swirl atomizer) and/or a heating element associated with a heating circuit and/or a heating tube. In some aspect, the systems and methods utilize received flow, temperature, and/or humidity information to determine an amount of water to add to breathing gases to reach a desired humidity of the breathing gases delivered to the patient. In further aspects, the humidification system can serve as a nebulization system for delivering nebulized medicine.

A device for an aspirator, the device comprising a suction inlet for suctioned air, liquid and particles; an exhaust outlet for air; a reservoir for collecting liquid and particles separated from the air; and a clearing arrangement fluidly between the suction inlet and the exhaust outlet, the clearing arrangement being configured to provide a path of air, substantially cleared from liquid sucked through the suction inlet, to the exhaust outlet, in any orientation of the device in space. An aspirator comprising a device, and a method of modifying a device for an aspirator, are also provided.

The Bone Dust Trap for collecting bone dust during various surgical procedures for subsequent bone graft implantation. The device includes cylindrical housing unit covered with the lid, attached to the central pipe with the porous tip. The pipe connects the cyclone forming mechanism and filtrating membrane, located at the lower part of the central pipe. The membrane interlinks with the plurality of porous plates located along the walls of the cylinder. The cyclone forming mechanism, consisting of the inlet port with conical jet and the spiral helix, creates spiral movement of the incoming fluid. The liquid is further directed towards the 2-stage filtrating system with the said porous plates, where larger bone particles are accumulated, and then to the filtrating membrane, which collects smaller particles. The fluid is extracted through the central pipe. The lid can be removed to collect the bone particles from plates and membrane.

The driving device for providing assisted ventilation comprises an air inlet (15), an impeller (7) provided with blades (8) rotatably driven by a motor (6), and an air outlet (5), the rotation of said impeller (7) being caused by the air circulation through a duct (4) from the air inlet (15) to the air outlet (5), wherein said blades (8) of the impeller (7) are flexible, vibrating at least one of its ends by the thrust caused by said circulating air.

It reduces noise to improve user comfort.

Therapeutic powder applicators and their methods of operation are described. In some embodiments, a first flow of gas may flow through a distal porous portion of a chamber containing a therapeutic powder. This gas may fluidize and entrain the therapeutic powder and flow the entrained powder through an outlet that is in fluid communication with the chamber.