Disclosed is a medicament dispenser (1) for delivering a medicament (9, 53) to a user (2), the medical dispenser (1) comprising one or more internal storages (3, 52) for storing one or more medicaments (9, 53); a dispensing unit (10, 101) configured to access said one or more internal storages (3, 52) and dispense the medicament (9; 53) based on a predefined dispensing protocol (18); a control unit (13) comprising a user recognition unit (12, 19), adapted to collect user authentication data (76); and a communication module (14), configured to send/receive said user authentication data (76) and a delivery control data (16) associated to said predefined dispensing protocol (18) to/from a remote server (15); wherein said control unit 5 (13) is configured to enable/disable said dispensing unit (10, 101) based on said user authentication data (76) and said delivery control data (16). Also disclosed is a medicament re-filling apparatus (32) for the use with a medicament dispenser (1) upon authentication and validation of its user (2) condition.

Provided is an extended use self-contained, wearable medical device. The device is preferably configured with an infusion deployment mechanism for variably inserting and retracting an infusion needle to different depths, or completely retracting the infusion needle from the infusion site and then re-inserting the infusion needle after a predetermined period of time, throughout an infusion cycle for extending the viability of the infusion site. Another embodiment comprises dual needle deployment mechanisms which may also variably insert and retract the infusion needles. A flow sensor is preferably provided for detecting the stoppage of flow through the infusion cannula and signaling the needle deployment mechanism to attempt infusion at a different depth or to deploy a second infusion needle. A re-fillable reservoir assembly is preferably provided for supplying a drug over the extended use of the device. Another embodiment comprises a partially reusable and partially disposable medical device implementing the above features.

A device is provided for delivering a predetermined volume of at least one substance within a body cavity of a subject. The device contains a) a capsule for containing the predetermined volume of substances; b) a delivery end, having at least one orifice of diameter D, for placement in proximity to the body cavity; c) a valve mechanically connectable to the capsule, having at least two configurations: (i) an active configuration in which the valve enables delivery of the substances; and (ii) an inactive configuration, in which the valve prevents delivery of the substances from the capsule to the body cavity; and d) a fluid tight chamber configured to contain predetermined volume V.sub.gas of pressurized gas at a predetermined pressure, P.sub.gas. The capsule further contains at least one mixing mechanism that mixes the substances and the pressurized gas after the valve is reconfigured to the active configuration.

A method of dispensing fluid includes three processes. A first one of these processes includes pumping fluid into a resilient variable-volume dispensing chamber. The dispensing chamber is in series with a normally present finite fluid impedance and an output. The impedance is sufficient so as to cause expansion of the dispensing chamber as it receives pumped fluid even while some fluid flows through the output. Another one of these processes includes repeatedly measuring a parameter related to volume of the dispensing chamber over time. A third one of these processes includes controlling the pumping of fluid based on repeated measurements of the parameter to produce a desired fluid flow through the output. A corresponding system for dispensing fluid implements these processes.

A filling aid. The filling aid includes a locking portion including a groove feature; and a locking feature having a locked and an unlocked position; and a filling syringe holder slidably attached to the locking portion, the filling syringe holder including a filling needle cradle portion having a tongue feature; and a needle housing portion comprising at least one tab having a starting position and a filling position, wherein the groove feature configured to accommodate the tongue feature, and wherein the locking feature interact with the filling syringe holder wherein when the locking feature moves from the locked position to the unlocked position the needle housing portion moves from the starting position to the filling position.

The present disclosure relates to an aerosol delivery device filling system. The system includes multiple source containers each respectively including a differing aerosol precursor composition. The system further includes a mixing container configured to engage the source containers to receive and mix the aerosol precursor compositions to form a mixed aerosol precursor composition. An aerosol delivery device may engage the mixing container to receive at least a portion of the mixed aerosol precursor composition. A related method for customizing an aerosol precursor composition is also provided.

A face mask (90) comprises an instrument shielding apparatus (91) which comprises an instrument shielding device (92) which is connected to the face mask (90) by an adapter (89). The adapter (89) comprises an instrument accommodating housing (15) through which an instrument bore (25) extends therethrough. The instrument accommodating housing (15) terminates at one end in a first main port (20) engageable with an instrument port (7) of the face mask (90), and in the other end in a second main port (23). The instrument shielding device (92) comprises a shielding sleeve (95) a first end (96) of which is secured by a coupling ring (98) to the second main port (23) of the adapter (89), and a second end (97) of which is secured in a storage chamber (94) of a sleeve storing housing (93) of the instrument shielding device (92). The sleeve storing housing (93) is sealably engageable with a proximal end (58) of an endoscope (10), and the shielding sleeve extends from a collapsed stored state in the storage chamber (94) to the adapter (89) for shielding the endoscope (10).

An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

A medical device system. The system includes a first medical device, a first remote interface, and a second remote interface in communication with the first remote interface and the first medical device, wherein the first medical device sends a command to the first medical device through the second remote interface, and wherein when the second remote interface receives the command, the command must be confirmed by the second remote interface before the command is send by the second remote interface to the first medical device.

In the field of medical dosing device filling, a propellant conditioning assembly (10) comprises an input conduit (12) to receive a propellant at a constant pressure from a propellant reservoir (102). The conditioning assembly (10) also includes a bifurcation (18) to divide the input conduit (12) into first and second conditioning conduits (20, 22). The first conditioning conduit (20) includes a cooler device (24) to selectively cool a diverted first propellant stream (26) that flows through the first conditioning conduit (20), and the second conditioning conduit (22) includes a heater device (32) to selectively heat a diverted second propellant stream (34) that flows through the second conditioning conduit (22). The conditioning assembly (10) still further includes an output conduit (44) to receive the first and second propellant streams (26, 34). The relative proportion of the first and second propellant streams (26, 34) merging in the output conduit (44) is controlled to regulate the temperature of a merged constant pressure propellant feed (46) exiting from the output conduit (44).