A surgical system comprises a pressurized irrigation fluid source; an irrigation line fluidly coupled to the pressurized irrigation fluid source; a hand piece fluidly coupled to the irrigation line; and a controller for controlling the pressurized irrigation fluid source. The controller controls the pressurized irrigation fluid source based on an estimated flow value modified by a compensation factor.

A drug injection device contains a needle holder, an ejector, a needle member, and an actuation assembly. The needle holder defines a drug delivery direction extending toward the injection end. The ejector contains a fixing segment that is fixed to the needle holder and located in the drug delivery direction, and the abutting segment extending toward the injection end and protruding beyond the needle holder. The needle member is movably arranged relative to the needle holder and contains a needle shaft connected to a needle hub coaxially arranged with the ejector for the abutting segment inserting into the needle shaft. The actuator assembly connects the needle holder and the needle shaft for driving the needle member between a first position and a second position with respect to the needle holder.

An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.

A work tip for an ultrasonic surgical hand piece has a solid knife with a sharp distal edge. A first fluid tube located on one side of the knife and has open ends to receive or discharge fluid. A second fluid tube is located on the other side of the knife and is slidably connected with the knife. The second fluid tube has an opening at a distal end and a smaller side hole. During phacoemulsification the knife is vibrated independent of the fluid tubes. The second fluid tube has irrigation fluid passing from the opening and side hole, and the first fluid tube is positioned so as to receive fluid from the second tube. During I/A cleanup the second fluid tube receives aspiration fluid only through the side hole because the knife is positioned to block the aspiration fluid from entering through the opening.

Glaucoma treatment systems are disclosed. In various example, the glaucoma treatment systems include a body and a fluid conduit configured to facilitate an evacuation of fluid, such as aqueous humor, from a fluid-filled body cavity, such as an anterior chamber of an eye. In some examples, the fluid conduit is soft and compliant, and the glaucoma treatment system includes one or more stiffening members coupled with the fluid conduit to temporarily stiffen the fluid conduit and help aid in the delivery of the glaucoma treatment device. In some examples, the stiffening members are removable from the fluid conduit after the glaucoma treatment system has been implanted.

Described here are systems and methods for accessing Schlemm's canal, for delivering a fluid composition therein, and for tearing the trabecular meshwork. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. The systems described here may be configured to cut or tear the trabecular meshwork with the body of an elongate member located within Schlemm's canal.

An apparatus for mechanically coupling a motor to a rotor includes an outer ring including an inner surface shaped to define multiple recesses, an inner ring disposed within the outer ring and shaped to define multiple compartments having respective outer openings, which face the outer ring, and respective inner openings opposite the outer openings, and multiple gripping elements disposed within the compartments, respectively. The inner ring is configured to receive the rotor while the compartments are aligned with the of recesses, by virtue of the gripping elements sitting at least partially within the recesses. The outer ring is configured to couple with a shaft coupled with the motor such that rotation of the shaft by the motor causes the compartments to become misaligned with the recesses, thereby causing the outer ring to push the gripping elements, through the outer openings, against the rotor, through the inner openings.

A virtual reality game- and biosignal sensor-based VOR assessment and rehabilitation apparatus includes: a biosignal sensing unit which senses and notifies of head movement and eye movement of a patient using an eye tracker and an inertial measurement unit (IMU) sensor attached or installed to a head-mounted display device; a VOR function assessment unit which configures and provides a game for VOR function assessment; a patient-personalization control unit which determines, on the basis of the VOR gain of the patient, the types and order of rehabilitation games, and a rehabilitation level; and a rehabilitation game providing unit which configures and provides games for at least one among smooth pursuit, saccades, VOR rehabilitation exercise, amplified VOR rehabilitation exercise, and suppressive VOR rehabilitation exercise, and determines the difficulty levels of the games on the basis of the rehabilitation level.

A system includes a mobile device having one or more cameras to take images; a sensor detecting reflected light from one or more lasers and a diffuser to detect object range or dimension; code for motion tracking, environmental understanding by detecting planes in an environment, and estimating light and dimensions of the surrounding based on the one or more lasers; code to estimate a three-dimensional (3D) volume of an object from multiple perspectives and from projected laser beams to measure size or scale and determine locations of points on the object's surface in a plane or a slice using time-of-flight, wherein positions and cross-sections for different slices are correlated to construct a 3D model of the object, including object position and shape; the device receiving user request to select a content from one or more augmented, virtual, or extended reality contents and rendering a reality view of the environment.

A cryo formulation-based microneedle device for ocular delivery of bioactive therapeutic agents. The microneedle device includes: one or more microneedle patches each including an array of miniaturized needles, wherein each miniaturized needle defining a base end and a tip; and a substrate to which the base end of the array of miniaturized needles is attached or integrated thereto; wherein the microneedle patch is in a cryo status; wherein each of the one or more microneedle patch is adapted to be applied on cornea of an eye, in which the miniaturized needles penetrates into the eye; and wherein the miniaturized needles is further arranged to melt so as to release one or more bioactive therapeutic agents into the eye to achieve a targeted therapeutic effect.