A patient interface for delivering breathable gas to a patient includes a sealing portion adapted to form a seal with the patient and a support portion to which the sealing portion is mounted. A first headgear chord is connected to a first side of the support portion, and a second headgear chord connected to a second side of the support portion. Headgear is adapted to connect to the first and second headgear chords to secure the support portion to a head of the patient. At least one adjustment device on the support portion is adapted to selectively move the first and second headgear chords to tighten or loosen the headgear.

A heat and moisture exchanger (HME) for engaging a patient’s nose while retrofit into a plenum chamber of a patient interface. The HME includes a frame configured to couple to a ridge of the patient’s nose, and a cradle coupled to the frame. The cradle is configured to be positioned proximate to the patient’s nares. The HME also includes an HME material coupled to the cradle. The HME material is configured to retain moisture exhaled by the patient. Air is configured to pass through the HME material when entering and exiting the patient’s nares. The HME engages and is secured to the patient’s nose independently of any other structure.

The present invention provides a respiratory mask comprising a nose cushion assembly. The nose cushion assembly comprises a base body and a buffering piece. The base body has a base intake portion, a base connection portion, and an air routing piece disposed at the inside of the base body and having a partitioning wall and a wall connection piece. The inside of the partitioning wall encloses an air intake zone. The wall connection piece is disposed outside the partitioning wall and connects with the base intake portion. Between the partitioning wall and the base intake portion there is defined an air outtake zone. The air intake zone is approximately at the center of the base intake portion. The buffering piece connects with the base connection portion and encloses a nose containing room, which in turn connects with the inside of the base body.

A headgear assembly includes a strap of a first flexible material with an elongate edge, and a second flexible material folded around and running along the elongate edge. The second flexible material may be an elastic material. The second flexible material may also cover an intersection or joint in the first flexible material such that the first flexible material may be made from two flexible materials layered together or joined end to end.

Provided is a ventilator that includes a breathing system, a mechanical system coupled to breathing system, and a control system coupled to breathing system and mechanical system. The control system includes pressure sensors, processing circuitry, and memory configured to store a look-up table. The processing circuitry receives a set of values for plurality of parameters, identifies a compression value from a plurality of compression values in the look-up table based on the received set of values. The processing circuitry causes the mechanical system to compress a bag valve of the breathing system in accordance with the identified compression value. The compression of the bag valve causes a gaseous inhalant to flow through the breathing system within a time-interval. The processing circuitry determines an actual volume of the gaseous inhalant and iteratively modifies the compression value of the bag valve to match a desired volume of the gaseous inhalant.

A device for delivering a predetermined amount of at least one substance to a body orifice of a subject includes a) a container for containing said at least one substance; b) a delivery end for placement in proximity to the orifice, the delivery end being in fluid communication with the container; c) a valve mechanically connectable to said container, characterized by at least two configurations: (i) an ACTIVE CONFIGURATION in which said valve enables delivery of predetermined amount of said substance from said container to said body orifice via said delivery end; and, (ii) an INACTIVE CONFIGURATION, in which said valve prevents delivery of said predetermined amount of said substance from said container to said body orifice; d) a trigger mechanism adapted to reconfigure said valve from said INACTIVE CONFIGURATION to said ACTIVE CONFIGURATION, and vice versa; and e) a fluid tight chamber.

Embodiments of the present invention provide a method for treatment of respiratory disorders such as asthma, chronic obstructive pulmonary disease, and chronic sinusitis, including cystic fibrosis, interstitial fibrosis, chronic bronchitis, emphysema, bronchopulmonary dysplasia and neoplasia. The method involves administration, preferably oral, nasal or pulmonary administration, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and an additive.

A nasal mask having a seal housing and a flexible nasal seal connected or connectable to the seal housing to define a mask cavity. The nasal seal extends between a face-contacting side and an outer side. The nasal seal has a contacting surface having an edge that defines a nose-receiving opening into the mask cavity and which is configured to seal about the user's nose. The nasal seal also has an under-nose support fixedly connected into the seal and which is configured to extend within the mask cavity and having a contact surface that is oriented to contact at least a portion of the under-nose surface of the user.

A nasal rinsing cap suitable for standard water bottle is disclosed. The body portion of the device can be attached to the top of the bottle. It has a cylindrical void matching the threaded portion of the bottle and a one-way fluid valve attached to another void extending from the cylindrical void and through the body portion. The body portion also includes a one-way air valve allowing the entry of air into the bottle. A top portion is removably or openably attached to the body portion. It has a tubular opening starting near the body portion and extending through the top portion. The top portion is configured so that it has a tip to be contacted with the user's nasal cavities. The top portion also has a pressure zone for closing the fluid valve by applying a pressure on it.

Sensing airflow and delivering therapeutic gas to a patient. At least one example embodiment is a method including: sensing, by a delivery device, that multiple breathing orifices are open to flow; and during a plurality of subsequent inhalations in which multiple breathing orifices are open to flow; and delivering, by the delivery device, a bolus of therapeutic gas to only one breathing orifice during each inhalation, and alternating delivery location in subsequent inhalations. The example delivering may further comprise: supplying therapeutic gas only from an accumulator during a first portion each inhalation; dispensing therapeutic gas from the accumulator and from a pressure regulator during a second portion of each inhalation, the second portion immediately subsequent to the first portion.