A controllable window of time is provided for waking a user from sleep. A system uses this window to variably control the acquisition of physiological data from a device such as a wearable monitor, such as by initiating data acquisition at the beginning of the window, and the acquired data can be used in turn to control when, during the window, an active alarm to the user might be provided. Using this technique, data acquisition from a physiological monitoring device or the like can be increased around the onset of the window to more accurately calculate a suitable waking time for the user within the window. This advantageously avoids the need for continuous, high-frequency data communications during long intervals of sleep, and focuses data transmission, related communications, and computing resources on those intervals when up-to-date data might be most useful for optimizing the user's wake up experience.

A blood filtration system can reduce the amount of plasma constituents (e.g., water and/or electrolytes) in the blood of the patient, and accordingly increase the hematocrit value of the patient. The blood filtration system (e.g., a controller, or the like) can determine a hematocrit value of a patient. The blood filtration system can determine a venous pressure of vasculature of a patient. The blood filtration system can compensate for pressure head in a component of a blood circuit (e.g., a withdrawal line of a catheter), for example to improve the accuracy of the venous pressure determination. The blood filtration system can determine one or more resistance characteristics of a blood circuit for the blood filtration system. The resistance characteristics can correspond to a resistance to a flow of blood through a component of the blood circuit.

Devices, kits and methods for determining the site of intramuscular injection in adult and child patients are disclosed. The device includes a top element and two legs that are configured to be fastened in a first position and a second position. When placed in the first position and second position, the device forms a substantially triangular region having a center that corresponds to the site of injection.

An example system for therapy delivery includes one or more processors configured to in response to a prediction indicating that the meal event is to occur, output instructions to an insulin delivery device to deliver a partial therapy dosage, to a device to notify the patient to use the insulin delivery device to take the partial therapy dosage, or to the insulin delivery device to prepare the partial therapy dosage prior to the meal event occurring, and in response to a determination indicating that the meal event is occurring (e.g., based on movement characteristics of a patient arm), output instructions to the insulin delivery device to deliver a remaining therapy dosage, to the device to notify the patient to use the insulin delivery device to take the remaining therapy dosage, or to the insulin delivery device to prepare the remaining therapy dosage.

A method of providing and/or injecting octreotide acetate to a subject in need thereof includes storing the octreotide acetate in a cartridge of a multi-use multi-dose injector provided with a variable dose setter and actuator. The injector includes a needle configured for subcutaneous administration of the octreotide acetate, the octreotide acetate having a concentration of 2,500 μg/mL. The method further includes permitting setting of a dose of the octreotide acetate by rotation of the variable dose setter. The injector is configured to provide at least one audible feedback during the rotation. The method further includes operating the actuator to deliver the octreotide acetate from the cartridge through the needle to treat the subject. The injector is provided with multiple surface portions.

A hand-operated device for enabling a patient to control a level of sedation. The device includes: an elongate arcuate portion arranged to fit around a wrist of a patient; and a switch arranged to activate upon compression across a width of the elongate arcuate portion.

A blood pressure lowering training device comprises a head frame unit corresponding to a user's head shape, an audio stimulation unit for broadcasting binaural beats with frequency following response to both ears of the user, a display unit including a display module for displaying a virtual image and blood pressure information and a blood pressure measurement module for measuring blood pressure, and a control unit electrically connected with the audio stimulation unit and the display unit, so that the hypertensive patient can perform a variety of adjustable blood pressure lowering training in one use process, and effectively improve the use intention of the hypertensive patient.

A ventilation apparatus has a breathing gas delivery system for delivering breathing gas to a user of the apparatus as ventilation therapy, with a controllable pressure and flow. The breathing pressure and flow are monitored to derive a respiration variability. A state of relaxation of the user is derived during provision of breathing assistance based on at least the respiration variability. Settings of the ventilation apparatus are then adapted dependence on the estimated state of relaxation for assisting the user in habituating to the breathing assistance, and hence habituating to breathing therapy.

A cognitive illusion of ownership over a proxy extremity (e.g. a hand) is provided by discordant touch and visual information to a user. While the user feels the touch on their real extremity, they see a corresponding touch on the proxy extremity. The user's internally modeled reality is then updated to move the felt location of the real extremity to the seen location of the proxy extremity. As a result, the user embodies the proxy extremity, thereby disembodying the real extremity. Pain associated with medical procedures performed on the real extremity is then mitigated. And because an epileptic brain is less stringent when resolving conflict between what is seen and what is felt, correlations in time or space can shift attribution of the sensation of the felt touch on the user's real extremity to the location of the proxy extremity. This can be helpful in treating and/or diagnosing epilepsy.

Devices and methods for controlling intracompartmental pressure in muscle compartments and, potentially, reducing the incidence of compartment syndrome are disclosed. A device according the invention is a thin, elongate member with an outer layer. The device has a proximal end, which has a coupling constructed and adapted to connect with tubing, and a distal end. The outer layer is at least somewhat permeable to liquids and to cells, either by way of perforations along its length or because of its natural properties. Within and encased by the outer layer lies a core, also porous, and typically an open-celled foam. The core is compressible under the range of suction pressures typically applied in medical contexts. A guide wire may initially be present in the device to aid in its placement. Methods for making such devices, especially on an ad hoc basis, are also disclosed.