A system to be implanted in a living body for supplying medical substance, such as insulin. The system has a first module (1) having an inlet port (5) for receiving a transcutaneous injection of the medical substance, a second module (2) having a reservoir for storing the medical substance; a first tube (3) allowing the medical substance to flow between the first module and the second module; and a catheter (4) for releasing the stored medical substance into the living body. The first tube (3) allows the first module and second module to be implanted at different locations in the living body.

Devices, systems, and methods herein relate to performing dialysis to manage a chronic condition such as end-stage renal disease. These systems and methods may allow a patient to orally ingest a potable dialysate and excrete the dialysate via the urinary tract. In some variations, a method may include delivering a dialysate via the esophagus of a patient and draining the dialysate into a bladder of the patient. Delivering the dialysate may further comprise delivering the dialysate through the nasopharynx or oropharynx. Delivering the dialysate through the oropharynx may comprise the patient drinking the dialysate.

Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that are configured to be implanted within a patient. The apparatuses, systems, and methods may include a catheter configured to implant within the intraperitoneal space of the patient, an interior flow lumen, and at least one opening connected to the interior flow lumen for therapeutic agent delivery.

The present disclosure provides devices and methods for insufflating abdomens of subjects under direct visualization. Such devices and methods, in some implementations, include features for cleaning the devices, and certain implementations of the methods permit procedures wherein it is not necessary to use a typical obturator to place a cannula, resulting in safer procedures.

The present disclosure provides devices and methods for insufflating abdomens of subjects under direct visualization. Such devices and methods, in some implementations, include features for cleaning the devices, and certain implementations of the methods permit procedures wherein it is not necessary to use a typical obturator to place a cannula, resulting in safer procedures.

A container system configured to transfer heat to a fluid contained within the container system, such as dialysate. The container system may be configured to fluidly couple to a medical machine. The container system includes a flexible material comprising a wall of the container system. In examples, the flexible material defines a container volume configured to contain the fluid. The flexible material mechanically supports a circuit configured to generate and transfer heat to the fluid. The circuit is configured to flex and/or bend when the flexible material flexes and/or bends. In examples, the container system includes control circuitry configured to cause the circuit to generate heat based on a temperature of the fluid.

A direct sodium removal (“DSR”) infusate regimen and methods of use are provided for removing sodium and reducing fluid overload in patients with severe renal dysfunction and/or heart failure, in which a patient has at least a first DSR session with a first DSR infusate having no or low sodium that is instilled into a patient's peritoneal cavity for a first dwell period to cause sodium and excess fluid to migrate to the patient's peritoneal cavity, and thereafter, the patient may undergo conventional dialysis to rebalance the patient's fluid and sodium levels.

The invention relates to an implantable device suitable for being fixed in a fixation position to a wall of a patient's stomach, the implantable device being accommodated in the stomach when the implantable device is in the fixation position, the implantable device being characterised in that it comprises a reserve of an active substance and an injector suitable for administering the active substance to the patient.

A dressing for treating a tissue site, particularly a peritoneal or abdominal site, is disclosed. The dressing may comprise: first and second layers, each being made from a liquid-impermeable material and being at least partially fenestrated, the layers being coupled together to define a chamber therebetween; and disposed within the chamber a third layer comprising a manifold having a central region, and a perimeter region containing perforations arranged in a pattern defining a plurality of sub-regions. The first and second layers can be coupled using a plurality of welds or bonds through the perimeter region perforations. Optionally, the manifold does not comprise, and the chamber does not contain, any manifolding elements extending outward from an outer edge of the perimeter region.

Filters for surgical procedures including a fluid pathway to transport fluid, such as smoke and/or gases, exhausted from a surgical site, a humidity regulating element located along the fluid pathway, and a filter element located downstream of the humidity regulating element such that the humidity regulating element and the filter element are in fluid communication with each other. The humidity regulating element is configured to remove or reduce humidity from the smoke and/or gases exhausted from the surgical site prior to the smoke and/or gases reaching the filter element. The filter element is configured to filter particulate matter from the smoke and/or gases exhausted from the surgical site.