Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

A urinary catheter assembly is provided. The catheter assembly has a first outer package (20), which contains a second inner package (1). The second inner package includes a hydrophilic coated, intermittent catheter 82) and liquid swelling medium. The first outer package is made of a first material with a WVTR value between 1 and 6 g/(m.sup.2.Math.24 h) and the second inner package is made of a second material with a second WVTR value below 3 g/(m.sup.2.Math.24 h). An intermediate cavity (25) is defined inside the first outer package, but outside the second inner package. The first and second WVTR-values are balanced in such a way that the relative humidity (RH) is below 90% in the intermediate cavity. This prevents condensation on the inner surface of the first outer package and on the outer surface of the second inner package.

A catheter for measuring pressure in the urinary tract of a patient includes a catheter body having a proximal and distal end. A plurality of lumens is formed in the catheter body, and an adaptor is coupled to the proximal end of the catheter body. The adaptor includes a port for each lumen. A first pressure sensor, typically including a balloon, is fluidically coupled to a first lumen and is configured and positioned to measure pressure in a urethra of the patient. A second pressure sensor, also typically including a balloon, is fluidically coupled to a second lumen and is configured and positioned on the catheter body to measure pressure in a bladder of the patient. An expandable retention member, which may be coupled to a third lumen, is positioned on the catheter body between the first and second expandable pressure sensors so that the catheter body may be retained at a selected location in the urinary tract to properly position the fluid pressure sensors in the bladder and urethra, respectively.

Urinary catheter-insertion kits can include a working tray, a storage tray, a urinary catheter, and a drainage system including drainage tubing and a drainage receptacle. The working tray can be configured to nest with the storage tray by suspending the working tray from the storage tray. At least the working tray includes a number of preformed sections configured to hold a number of components of the urinary catheter-insertion kit. At least one section of the preformed sections of the working tray includes a catheter section configured to hold the urinary catheter. The storage tray can be configured to hold the drainage system. Methods of urinary catheterization include use of the urinary catheter-insertion kits.

A urinary catheter assembly includes a first outer package having a first material, a second inner package contained inside of the first outer package, and an intermediate cavity defined as an area inside the first outer package and outside the second inner package. The first material has a first water vapour transmission rate (WVTR) measured according to ASTM F1249 at 90% relative humidity (RH) and 38° C. between 1 g/(m2.Math.24 h) and 6 g/(m2.Math.24 h). The second inner package has a second material having a second WVTR measured according to test method A at 65% RH and 30° C. below 3 g/(m2.Math.24 h). The second inner package contains a swelling medium and an intermittent urinary catheter with a hydrophilic coating.

An apparatus for treating urinary retention of a patient by discharging urine from the urinary bladder. The apparatus comprises an expandable member, adapted to be implanted inside the urinary bladder of a patient, for discharging urine from the urinary bladder as a result of its expansion in volume, an implantable control device for controlling the volume of the expandable member, and an external energy transmission device for wireless transmission of energy from the outside of the patient's body to the inside of the patient's body configured to operate the expandable member and other energy consuming implantable parts of the apparatus.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

A system for removing fluid from a urinary tract includes: at least one sensor configured to detect signal(s) representative of bioelectrical impedance and communicate signal(s) representative of the impedance; and a controller. The controller is configured to: receive and process the signal(s) from the at least one sensor to determine if the impedance is above, below, or at a predetermined value; and provide a control signal, determined at least in part from the signal(s) representative of the impedance received from the at least one sensor, to a negative pressure source to apply negative pressure to a urinary catheter when the impedance is below the predetermined value and to cease applying negative pressure when the impedance is at or above the predetermined value.

The present invention relates to a filtering device for removing particles from a bodily fluid of a patient, the filtering device being implantable in the patient's body. The device has a tube forming a main fluid passageway for bodily fluid, through which the bodily fluid of the patient passes when the tube is implanted in the patient, a filter connected to the tube and a filter cleaning device for cleaning the filter by moving particles collected by the filter out of the fluid passageway, wherein the filter cleaning device is adapted to replace the first filter in the fluid passageway with a second filter, thereby moving the particles collected by the first filter out of the fluid passageway.

The present disclosure describes a system for the delivery of therapeutic substances to the cavities of a patient. The system can include a wearable micropump that is fluidically coupled with a handpiece. The handpiece can be inserted, for example, into the middle ear via a surgical tympanotomy approach. The system can enable a controlled injection of a therapeutic substance directly into the patient's cavity.