The present technology is generally directed to shunting systems having shape memory actuation elements that can selectively change a geometry of a shunting element to affect the flow of fluid therethrough. In some embodiments, the shape memory actuation elements are incorporated as part of an onboard resonant circuit. Activating the resonant circuit causes current to flow through the shape memory actuation element, thereby resistively heating the shape memory actuation element.

Methods related to catheter-based procedures are provided. Aspects of the methods of embodiments of the invention include performing a catheter-based procedure and communicating data regarding the catheter-based procedure to and/or from a catheter-based procedure information module. Catheter-based procedure information modules may be remote modules. Also provided are systems comprising a first processor comprising memory operably coupled to the first processor, wherein the memory comprises instructions stored thereon, which, when executed by the first processor, cause the first processor to: receive data regarding a catheter-based procedure from a catheter-based system, and transmit data regarding a catheter-based procedure to a catheter-based system. Also included in systems of embodiments of the invention is a catheter-based system, comprising: a catheter-based device, a second processor comprising memory operably coupled to the second processor, wherein the memory comprises instructions stored thereon, which, when executed by the second processor, cause the second processor to: transmit data regarding the catheter-based procedure to the catheter-based procedure information module, receive data regarding the catheter-based procedure from the catheter-based procedure information module, and configure the catheter-based device based at least in part on data regarding the catheter-based procedure received from the catheter-based procedure information module. Also included in systems of embodiments of the invention is an operable connection between the catheter-based procedure information module and the catheter-based system. In addition, non-transitory computer readable storage mediums configured to perform the methods described herein are provided. The methods, systems and non-transitory computer readable storage mediums find use in a variety of different applications, including balloon angioplasty applications or other catheter-based procedures, therapies or treatments.

An inserter for guiding a device through a hemostasis valve. The inserter comprises an elongate tubular body, a concave landing zone, and an axially extending slit. The elongate body tubular body of the inserter partially defines a central lumen. A method a of passing a device through a valve comprises the steps of providing an inserter having a tubular body with a split sidewall, advancing the tubular body through a valve, advancing a device through the tubular body and beyond the valve and retracting the tubular body so that the device escapes laterally from the tubular body through the split sidewall, leaving the device in place across the valve.

A device for stabilizing catheters such as delivery catheters is disclosed. The device includes a radially expandable structure which extends from a proximal end to an opposing distal end. The expandable structure is secured to a stabilizer catheter at its proximal end. The device includes means to position the delivery catheter relative to the expandable structure. The means may include one or more attachment members arranged to extend distally from the distal end of the expandable structure. Each attachment member is coupleable to a connector projecting near a distal tip of the delivery catheter. The means may alternatively include one or more sleeves, each arranged for the respective one of the delivery catheters to insert therethrough. A retractable catheter sheath is moveable along the longitudinal axis of the expandable structure to extend the expandable structure between a compressed configuration and an expanded configuration. A kit for stabilizing catheters is also enclosed. The kit includes a delivery catheter. The delivery catheter may comprise a connector projecting near a distal end thereof for coupling the attachment member. A method of use of the device for the delivery of biocompatible materials is also disclosed.

Systems and methods for improving kidney function. A first mechanical circulatory support system (MCS) is introduced in a patient's heart, and a second mechanical circulatory support system is introduced in a patient's inferior vena cava or renal vein. The second mechanical circulatory support system is operated while the first mechanical circulatory support system is operating. A renal parameter is monitored during. Combined operation of the two mechanical circulatory support systems results in a change in renal parameter, e.g. pressure drop in the renal vein, indicating an improvement in kidney function. Once the renal parameter is determined to be below a target threshold, operation of the second mechanical circulatory support device is stopped.

Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.

The invention provides methods of treating an obstructive coronary artery disease in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof and performing a coronary artery bypass graft procedure on the subject.

The invention relates to a device for treating an individual suffering from cardiac or circulatory arrest or from a stroke, comprising a blood withdrawal device (BE) that is applied to the individual (P), an analysis unit (BA) which is directly or indirectly connected to the blood withdrawal device for detecting a blood analysis result (BAE) providing at least one characteristic of the blood, directly or indirectly connected to a blood return device (BR) that is applied to the individual (P) and is designed to deliver a substance to the individual via the return device (BR).

The present invention relates to a cytopheretic cartridge for use in treating and/or preventing inflammatory conditions that affect myocardial function and to related methods. The cartridge can be used in treating a subject with myocardial dysfunction, such as a subject with chronic heart failure and/or acute decompensated heart failure.

A catheter includes a tip electrode with a shell and a support member to provide a plenum chamber. The plug is formed with a U-shaped passage for a safety line to wrap around and secure the support member (with the shell affixed thereto) to the catheter. Additional passages are formed in the plug to accommodate components such as irrigation tubing, lead wire and thermocouple wire pair. A method of manufacture provides distal installation and/or anchoring of the safety line, lead wire and thermocouple wire pair in the support member prior to sealing the support member and mounting the shell.