The present invention provides new devices, systems, and methods for delivering enriched oxygen to recipients (e.g., chronically ill patients, such as COPD patients). One aspect is a more efficient portable oxygen concentrator that is configured to deliver an enriched oxygen airflow having a significantly lower overall oxygen concentration and greater overall volume administered as compared to currently marketed or known portable oxygen concentrators. Administering the lower oxygen concentration at higher volumes allows for the present portable oxygen concentrators to deliver an equivalent number of moles of oxygen as administered by traditional portable concentrators while increasing the efficiency of the system and the ability of the system to maintain the therapeutic level of oxygen concentration for a longer period.

The present invention provides new devices, systems, and methods for delivering enriched oxygen to recipients (e.g., chronically ill patients, such as COPD patients). One aspect is a more efficient portable oxygen concentrator that is configured to deliver an enriched oxygen airflow having a significantly lower overall oxygen concentration and greater overall volume administered as compared to currently marketed or known portable oxygen concentrators. Administering the lower oxygen concentration at higher volumes allows for the present portable oxygen concentrators to deliver an equivalent number of moles of oxygen as administered by traditional portable concentrators while increasing the efficiency of the system and the ability of the system to maintain the therapeutic level of oxygen concentration for a longer period.

An implantable glymphatic pump configured to flush metabolites from a brain parenchyma of a patient. The implantable glymphatic pump including at least one spinal catheter having a distal end configured to be positioned within an intrathecal space of a spine of a patient, at least one cranial catheter having a distal end configured to be positioned within a brain parenchyma of the patient, and an implantable pump configured to draw cerebrospinal fluid from the intrathecal space of the spine in the patient via the at least one spinal catheter, and reintroduce said cerebrospinal fluid to the brain parenchyma of the patient via the one or more cranial catheters to encourage a flow of the cerebrospinal fluid through the brain parenchyma.

An operating unit (2) sets ventilation parameters of a control unit (11) of a ventilator (1) that includes a gas dispensing device (10) for ventilation gases. The operating unit includes a display unit and an ventilation parameters input element (23, 24). Two or more of the parameters are linked via a relation condition stored in a relation storage module (40). A relation monitor (3) includes a deviation detector (31) detecting a transgression of the relation condition during parameter setting, and outputs warning information via a warning unit (32). This avoids a need for an operator to note the sometimes complicated connections and dependencies expressed in the relations during the parameter setting. The warning may be sent before the new setting value is sent from the operating unit to the control unit. Operating safety is increased and a risk of setting errors is minimized.

There is provided an IV infusion set comprising a patient access configured to connect to a vascular system of a patient, a source of medical fluid, an infusion line having one first end configured to connect to the source of medical fluid and one opposite second end configured to deliver the medical fluid towards the patient access, an infusion apparatus arranged on the infusion line, a sensor configured to emit a pressure signal indicative of a pressure of a medical fluid in the infusion line, and a control unit configured to receive the pressure signal and to determine a patient signal indicative of a vital signal of the patient based on the pressure signal. The IV infusion set further comprises a compliance element configured to attenuate pressure variations of medical fluid the infusion line, and a resistance element configured to reflect pressure waves moving along the infusion line. The sensor is arranged on the infusion line at a position downstream from the resistance element with respect to a direction of fluid flow along the infusion line from the medical fluid source towards the patient access. The infusion line may include a main infusion line and/or one or more auxiliary infusion lines connected to a main infusion line.

Aspects of the subject disclosure may include, for example, receiving information about a task to be completed by a user, receiving information about the user and receiving information about a physical environment of the user. The subject disclosure may further include creating one or more immersion objects based on the information about the task, the information about the user and the information about the physical environment, creating an immersive environment including the one or more immersive objects and at least a portion of the physical environment of the user, and communicating to an extended reality (XR) device of the user information about the immersive environment to create an immersive experience for completion of the task by the user. Other embodiments are disclosed.

Aspects of the subject disclosure may include, for example, receiving information about a task to be completed by a user, receiving information about the user and receiving information about a physical environment of the user. The subject disclosure may further include creating one or more immersion objects based on the information about the task, the information about the user and the information about the physical environment, creating an immersive environment including the one or more immersive objects and at least a portion of the physical environment of the user, and communicating to an extended reality (XR) device of the user information about the immersive environment to create an immersive experience for completion of the task by the user. Other embodiments are disclosed.

Embodiments provide an oxygen supply device having multiple operational states including a first state and a second state. In the first state, the oxygen supply device is controllable to a local control instruction such that the oxygen supply device can be operated by a user physically located within a proximity of the oxygen supply device. In the second state, the oxygen supply device is only controllable to a remote-control instruction such that the oxygen supply device can be operated by a user remote to the oxygen supply device. For example, the user can be located in an office remote to a location of the oxygen supply device, which, for example, may be placed at a patient’s home. In the second state, the user is enabled to control the oxygen supply device from a device associated with the user in the remote location.

Aspects of the present disclosure provide methods, apparatuses, and systems for closed-loop sleep protection and/or sleep regulation. According to an aspect, sleep disturbing noises are predicted and a biosignal parameter is measured to dynamically mask predicted disturbing environmental noises in the sleeping environment with active attenuation. Environmental noises in a sleeping environment of a subject are detected, input, or predicted based on historical data of the sleeping environment collected over a period of time. The biosignal parameter is used to determine sleep physiology of a subject. Based on the environmental noises in the sleeping environment and the determined sleep physiology, the noises are predicted to be disturbing or non-disturbing noises. For predicted disturbing noises, one or more actions are taken to regulate sleep and avoid sleep disruption by using sound masking prior to or concurrently with the occurrence of the predicted disturbing noises.

Aspects of the present disclosure provide methods, apparatuses, and systems for closed-loop sleep protection and/or sleep regulation. According to an aspect, sleep disturbing noises are predicted and a biosignal parameter is measured to dynamically mask predicted disturbing environmental noises in the sleeping environment with active attenuation. Environmental noises in a sleeping environment of a subject are detected, input, or predicted based on historical data of the sleeping environment collected over a period of time. The biosignal parameter is used to determine sleep physiology of a subject. Based on the environmental noises in the sleeping environment and the determined sleep physiology, the noises are predicted to be disturbing or non-disturbing noises. For predicted disturbing noises, one or more actions are taken to regulate sleep and avoid sleep disruption by using sound masking prior to or concurrently with the occurrence of the predicted disturbing noises.