An apparatus and method use a catheter for specific and discriminate treatment of central nervous system disease. With the catheter, selective hypothermia to the brain and/or the spinal cord for injury protection can be achieved without the need for systemic cooling. The catheter is also capable of draining excess cerebrospinal fluid.

A lighting system for establishing a database of multispectral circadian rhythm lighting scenario and psychological stress indicators is configured in space, which is characterized by downloading the multispectral circadian rhythm lighting scenario database from the cloud; the multispectral lighting parameters and circadian rhythm parameters are selected from the multispectral circadian rhythm lighting scenario database to start the light-emitting device for lighting; the ambient light sensor measures and judges whether the circadian rhythm parameters reach the set value; when each circadian rhythm parameter in the circadian rhythm lighting scenario database has reached the set value, the light-emitting device is started for lighting; after the blood or saliva of the light control subjects were tested, the psychological stress index values of the illuminators were obtained; the portable communication device transmits the circadian rhythm parameters and psychological stress index values to the cloud; among them, the circadian rhythm parameters include: circadian rhythm lighting parameters and circadian rhythm scenario parameters.

A lighting system for establishing a database of multispectral circadian rhythm lighting scenario and psychological stress indicators is configured in space, which is characterized by downloading the multispectral circadian rhythm lighting scenario database from the cloud; the multispectral lighting parameters and circadian rhythm parameters are selected from the multispectral circadian rhythm lighting scenario database to start the light-emitting device for lighting; the ambient light sensor measures and judges whether the circadian rhythm parameters reach the set value; when each circadian rhythm parameter in the circadian rhythm lighting scenario database has reached the set value, the light-emitting device is started for lighting; after the blood or saliva of the light control subjects were tested, the psychological stress index values of the illuminators were obtained; the portable communication device transmits the circadian rhythm parameters and psychological stress index values to the cloud; among them, the circadian rhythm parameters include: circadian rhythm lighting parameters and circadian rhythm scenario parameters.

Adaptive modification and presentment of user interface elements in a computerized therapeutic treatment regimen. Embodiments of the present disclosure provide for non-linear computational analysis of cData and nData derived from user interactions with a mobile electronic device executing an instance of a computerized therapeutic treatment regimen. The cData and nData may be computed according to one or more artificial neural network or deep learning technique to derive patterns between computerized stimuli or interactions and sensor data. Patterns derived from analysis of the cData and nData may be used to define an effort metric associated with user input patterns in response to the computerized stimuli or interactions being indicative of a measure of user engagement or effort. A computational model or rules engine may be applied to adapt, modify, configure or present one or more graphical user interface elements in a subsequent instance of the computerized therapeutic treatment regimen.

Adaptive modification and presentment of user interface elements in a computerized therapeutic treatment regimen. Embodiments of the present disclosure provide for non-linear computational analysis of cData and nData derived from user interactions with a mobile electronic device executing an instance of a computerized therapeutic treatment regimen. The cData and nData may be computed according to one or more artificial neural network or deep learning technique to derive patterns between computerized stimuli or interactions and sensor data. Patterns derived from analysis of the cData and nData may be used to define an effort metric associated with user input patterns in response to the computerized stimuli or interactions being indicative of a measure of user engagement or effort. A computational model or rules engine may be applied to adapt, modify, configure or present one or more graphical user interface elements in a subsequent instance of the computerized therapeutic treatment regimen.

One variation of a method for delivering a digital medicine experience to a user includes: loading the digital medicine experience at a sensory immersion vessel; calculating a target value of a bioindicator of the physiological state of the user, the target value of the bioindicator corresponding to a target physiological state of the user; at an initial time, rendering sensory representations of a set of elements in a multi-sensory virtual environment within the sensory immersion vessel at an initial progression rate; at a time during the digital medicine experience, succeeding the initial time, measuring a value of the bioindicator; calculating a progression rate through the digital medicine experience based on a difference between the value of the bioindicator and the target value of the bioindicator; and at a second time succeeding the time, rendering sensory representations of the set of elements in the multi-sensory virtual environment at the progression rate.

One variation of a method for delivering a digital medicine experience to a user includes: loading the digital medicine experience at a sensory immersion vessel; calculating a target value of a bioindicator of the physiological state of the user, the target value of the bioindicator corresponding to a target physiological state of the user; at an initial time, rendering sensory representations of a set of elements in a multi-sensory virtual environment within the sensory immersion vessel at an initial progression rate; at a time during the digital medicine experience, succeeding the initial time, measuring a value of the bioindicator; calculating a progression rate through the digital medicine experience based on a difference between the value of the bioindicator and the target value of the bioindicator; and at a second time succeeding the time, rendering sensory representations of the set of elements in the multi-sensory virtual environment at the progression rate.

A device, system, and method for facilitating a sleep cycle in a subject suing a peri COVID vaccination period, comprising determining a current awake or sleep stage of a person; automatically defining a desired sleep cycle pattern, dependent on the current awake or sleep stage of the person; generating an audio or optical stimulation pattern by an automated processor; entraining brainwaves of the brain of the person with the stimulation pattern corresponding to the desired sleep cycle pattern, to thereby induce a sleep cycle in the person according to the sleep cycle pattern; and administering the SARS-Cov-2 vaccination to the person.

An ear-worn electronic device includes a right ear device comprising a first processor and a left ear device comprising a second processor communicatively coupled to the first processor. A physiologic sensor module comprises one or more physiologic sensors configured to sense at least one physiologic parameter from a wearer. A motion sensor module comprises one or more sensors configured to sense movement of the wearer. The first and second processors are coupled to the physiologic and motion sensor modules. The first and second processors are configured to produce a three-dimensional virtual sound environment comprising relaxing sounds, generate verbal instructions within the three-dimensional virtual sound environment that guide the wearer through a predetermined mental exercise that promotes wearer relaxation, and generate verbal commentary that assesses wearer compliance with the predetermined mental exercise in response to one or both of the sensed movement and the at least one physiologic parameter.

A system and method for brainwave entrainment using virtual objects and gamification, in which brainwave entrainment is applied using some combination of gaming elements, brainwave is enhanced by virtue of the user's active participation, and long-term use is encouraged by virtue of the entertaining nature of the gamification. Depending on configuration, the system and method may comprise a display comprising virtual objects, a light-producing device (other than the display), an audio-producing device such as speakers or headphones, a haptic feedback device such as a vibratory motor, a means for monitoring the user's attention, and a software application which applies brainwave entrainment using some combination of the display, the light-producing device, the audio-producing device, and the haptic feedback device.