The systems, devices, and methods described herein relate to providing breathing gas to a patient using a base unit and an auxiliary unit configured to be removably disposed on or at least partially in the base unit. The base unit has several couplings for improved control and sensing of the auxiliary unit and its components, wherein the couplings are configured to be non-contact with the corresponding components of the auxiliary unit and/or otherwise configured to minimize operational defects or improve efficiency. Non-contact couplings include induction heating, capacitive level sensing, a magnetically coupled rotor pump, RFID tag and reader, and Hall effect sensing. The breathing gas can be provided at high velocities by setting breathing gas flowrates based on dimensions of a nasal cannula used to direct the breathing gas into a patient's nares.

The systems, devices, and methods described herein relate to providing breathing gas to a patient using a base unit and an auxiliary unit configured to be removably disposed on or at least partially in the base unit. The base unit has several couplings for improved control and sensing of the auxiliary unit and its components, wherein the couplings are configured to be non-contact with the corresponding components of the auxiliary unit and/or otherwise configured to minimize operational defects or improve efficiency. Non-contact couplings include induction heating, capacitive level sensing, a magnetically coupled rotor pump, RFID tag and reader, and Hall effect sensing. The breathing gas can be provided at high velocities by setting breathing gas flowrates based on dimensions of a nasal cannula used to direct the breathing gas into a patient's nares.

A method for invasive cardiac treatment, including inserting a catheter via a transvascular route into a beating heart of a patient who is anesthetically paralyzed and intubated for ventilation, and, after inserting the catheter, temporarily halting ventilation of the patient. The method includes moving the catheter between a plurality of locations of myocardial tissue of the heart while the ventilation is halted; and ablating the myocardial tissue of the heart at the plurality of locations while the ventilation is halted.

A method for invasive cardiac treatment, including inserting a catheter via a transvascular route into a beating heart of a patient who is anesthetically paralyzed and intubated for ventilation, and, after inserting the catheter, temporarily halting ventilation of the patient. The method includes moving the catheter between a plurality of locations of myocardial tissue of the heart while the ventilation is halted; and ablating the myocardial tissue of the heart at the plurality of locations while the ventilation is halted.

The present disclosure pertains to a system and method for monitoring lung disease in a patient that is based on information that is derivable from home therapy devices including a ventilation therapy device and an oxygen saturation monitor such as a pulse oximeter. The measured parameters are used to model shunt fraction and a volume of dead space. Based on changes in gas exchange and results of a nitrogen washout test, a change in gas exchange impairment in the patient is observed and is then used to determine progression of a disease, identify a cause of the impairment, and/or to guide treatment of the patient.

The present disclosure provides systems for controlling infusion of one or more supplements into blood received from a patient. The systems may include at least one extracorporeal circulatory support system including a pump, fluid conduits, and at least one sensor configured to measure one or more parameters of the blood. The system also may include a fluid flow regulator coupled to the extracorporeal circulatory support system; and a processor, a memory, and associated circuitry communicatively coupled to the at least one sensor and the at least one fluid flow regulator. The system receives measurement signals corresponding to parameters of blood from the at least one sensor and determines one or more target values for the parameters of blood based on a patient profile and/or the measurements. The system may control the fluid flow regulator to cause an infusion of at least one supplemental fluid from a supplemental fluid source into the blood.

The present invention relates to a system (10) and a corresponding method for estimating the respiratory drive (R_DRIVE) of mechanically ventilated patients, and for preferably apportioning this respiratory drive into one, or more, components related to the chemical drive—i.e. the drive due to the chemoreceptor response—and/or the muscular drive—i.e. the contraction of respiratory muscles, for example the diaphragm. The principle of the invention is that respiratory drive can be obtained from measuring the patient's response to small changes in mechanical ventilation settings (Vt_SET), and that this can be apportioned into chemical and/or muscular effects depending upon the changes in respiratory frequency, and/or arterial or end tidal CO.sub.2 levels, and/or arterial blood p H.

The oxygen therapy system receives data for an elapsed time such as a flow rate value of the oxygen gas, and a blood oxygen level or a level of carbon dioxide partial pressure in arterial blood (PaCO2) of a user, from the oxygen supply device which controls a flow rate of the oxygen gas for inhalation based on the blood oxygen level or the carbon dioxide partial pressure in arterial blood (PaCO2) of the user so that the blood oxygen level or level of carbon dioxide partial pressure in arterial blood (PaCO2) is in a prescribed range. The system calculates a proportion of a duration for each oxygen gas flow rate during which the blood oxygen level or carbon dioxide partial pressure in arterial blood (PaCO2) is in the prescribed range from the acquired data in which the oxygen gas flow rate fluctuates with the blood oxygen level or carbon dioxide partial pressure in arterial blood (PaCO2), and displays the calculated data as a histogram or pie graph on a terminal which a healthcare worker such as a physician operates.

A method of determining a duration of safe apnoea. Information is obtained relating to a respiratory indicator, and a duration of safe apnoea is determined from the obtained information. A respiratory therapy system has one or more patient interfaces. A processor is configured to determine a duration of safe apnoea based on obtained information relating to a respiratory indicator.

An oxygenator (10) for an extracorporeal ventilation system comprises a gas passage and a blood passage arranged to allow gas exchange of an oxygenation gas supply with blood via a gas-blood interface (34). The gas passage leads from a gas inlet zone (28) via the gas-blood interface (34) to a gas exhaust zone (40). The blood passage leads from a blood inlet (12) via the gas-blood interface (34) to a blood outlet (14). The oxygenator comprises a supply gas distribution arrangement (26, 28A, 28B). This allows the oxygenation gas supply to be modulated differently for different interface regions of the gas-blood interface. The oxygenator can be used to remove or reduce the formation of gaseous microemboli bubbles.