A catheter configured to be deployed in a urinary tract of a patient includes a proximal portion configured to pass through a percutaneous opening and a distal portion including a retention portion. The retention portion is configured to be deployed in a kidney, renal pelvis, and/or bladder of the patient. The retention portion includes one or more protected drainage holes, ports or perforations and is configured, when deployed, to establish an outer periphery or protective surface area that inhibits mucosal tissue from occluding the one or more protected drainage holes, ports, or perforations upon application of negative pressure through the catheter.

A plasmapheresis system and a method for operating a plasmapheresis system are provided by which the volume/weight of anticoagulated plasma that is collected is optimized. In one example, a nomogram is provided that utilizes the donor's hematocrit to calculate the volume/weight of raw plasma within a plasma product having the maximum volume permitted by the FDA nomogram. In a plasmapheresis procedure having multiple collection phases followed by a reinfusion cycle in which concentrated red blood cells are returned to the donor, the volume of plasma product to be collected is calculated prior to the start of each collection cycle to account for the donor's increasing hematocrit, thus resulting in a greater total volume of plasma product to be collected during the plasmapheresis procedure.

A computer-implemented method and a computer system are disclosed. The computer system (200, 300) is suitable for detecting an operating state of a blood treatment machine (100, 201, 202, 20 . . . , 20n) or of a course of treatment in a blood treatment or a deviation from an ideal or uncomplicated operating state or a course of treatment. The computer system comprises a first interface (20, 312), which is adjusted to receive an operating parameter monitoring signal, wherein the operating parameter monitoring signal represents a time-dependent signal of a sensor for monitoring an operating parameter of the blood treatment machine or a signal derived from the time-dependent signal of the operating parameter, and a second interface (20, 312), which is adjusted to receive a user response signal, wherein a user response signal represents a signal of a user input with respect to the operating state or the course of treatment or the deviation from the ideal or uncomplicated course of treatment or operating state of a blood treatment performed using the blood treatment machine. The computer system additionally comprises an evaluation unit (40, 213), which is adjusted to generate allocation data or reference data, establishing a correlation between a determined user response and a respective operating parameter monitoring signal, a memory unit, which is configured to save the allocation data and reference data, wherein the evaluation unit is also adjusted to compare a determined operating parameter monitoring signal with the allocation data or reference data to derive from this an operating state, a course of treatment or a deviation from an ideal or uncomplicated operating state or course of treatment of the blood treatment machine or a typical user response thereto.

Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices include the use of a RBC flocculant, such as polyDADMAC, and an approximate blood hematocrit for the type of animal, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal type hematocrit, and a calculated RBC packing ratio “η” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

A blood filtration system can reduce the amount of plasma constituents (e.g., water and/or electrolytes) in the blood of the patient, and accordingly increase the hematocrit value of the patient. The blood filtration system (e.g., a controller, or the like) can determine a hematocrit value of a patient. The blood filtration system can determine a venous pressure of vasculature of a patient. The blood filtration system can compensate for pressure head in a component of a blood circuit (e.g., a withdrawal line of a catheter), for example to improve the accuracy of the venous pressure determination. The blood filtration system can determine one or more resistance characteristics of a blood circuit for the blood filtration system. The resistance characteristics can correspond to a resistance to a flow of blood through a component of the blood circuit.

The invention relates to a device and method for determining the haematocrit and/or haemoglobin level of a liquid flowing in a tubular portion (2), the method comprising:—emitting light beams in the direction of the tubular portion (2) with at least two light sources (11; 21), each of the two light sources (11; 21) being configured to emit light beams at an emission wavelength chosen to correspond to an isobestic point of the haemoglobin;—receiving light signals transmitted through the tubular portion (2) with at least two light sensors (12; 22), each light sensor (12; 22) being associated with one of the two light sources (11; 21);—calculating the haematocrit or haemoglobin level in the liquid by processing the light signals received by the light sensors (12; 22); characterised in that the emission power of at least one of the light sources (11; 21) is modified while the haematocrit and/or the haemoglobin level is determined according to the haematocrit and/or respectively the haemoglobin level calculated for the liquid.

Described is a method for controlling fluid volume balance. A controller is configured with a first set of inputs comprising a hematocrit, a total blood volume, and an ACD ratio. A maximum extracorporeal RBC amount during the procedure is estimated based on the first set of inputs. A fluid circuit is primed with a priming fluid. Whole blood is drawn from a blood source and separated into a RBC component, a target cell component, and a plasma component. The target cell component is directed to a product container. The product container comprising the target cell component is treated. A treated target cell component, a portion of the RBC component remaining in the fluid circuit, and/or a portion of the plasma component remaining in the fluid circuit are returned to the blood source. A first response action is provided if the maximum extracorporeal RBC amount estimated is above a programmed limit.

Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices include the use of a RBC flocculant, such as polyDADMAC, and an approximate blood hematocrit for the type of animal, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal type hematocrit, and a calculated RBC packing ratio “η” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

A monitoring system for cardiac operations with cardiopulmonary bypass comprising: a processor operatively connected to a heart-lung machine; a pump flow detecting device connected to a pump of the heart-lung machine to continuously measure the pump flow value and send it to the processor; a hematocrit reading device inserted inside the arterial or venous line of the heart-lung machine to continuously measure the blood hematocrit value and to send it to the processor; a data input device to allow the operator to manually input data regarding the arterial oxygen saturation and the arterial oxygen tension; computing means integrated in the processor to compute the oxygen delivery value on the basis of the measured pump flow, the measured hematocrit value, the preset value of arterial oxygen saturation, and the preset value of arterial oxygen tension; and a display connected to the processor to display in real-time the computed oxygen delivery value.

A device for determining the level of haematocrit and/or the level of haemoglobin of a liquid circulating in the tubular portion includes two emitter-receiver assemblies, each emitter-receiver assembly including a light source and a light sensor intended to be arranged on either side of the tubular portion at a region of circulation of the liquid for a transmission measurement; the light source of each of the two emitter-receiver assemblies being configured to emit light beams at an emission wavelength chosen to correspond with an isobestic point of haemoglobin; each emitter-receiver assembly further comprising including a system for collimating the light beam emitted from the corresponding light source towards the corresponding light sensor.