Disclosed herein are systems and methods for increasing performance, improving sleep and improving relaxation that involve specifically coordinating nerve stimulation of a cranial nerve (e.g. vagus nerve) in conjunction with augmented reality (AR). According to certain embodiments disclosed are systems that include an AR component that presents information or a stimulus and provides cranial nerve fiber stimulation (CNFS) at strategic times to reduce anxiety/arousal/related during user activity or scenarios and reinforce learning.

Devices, systems, and methods for monitoring respiration using surface temperature, humidity, air pressure, carbon dioxide gas sensors, pulse oximetry sensors and electromyography sensors, and/or acceleration sensors to obtain information related to respiration rate (RR), exhalation/inhalation strength, exhalation/inhalation volume, exhalation/inhalation acceleration, and/or exhalation/inhalation regularity.

According to certain embodiments, an apparatus for applying negative pressure to a wound can include a negative pressure source, a sensor, and a controller. The negative pressure source can be configured to couple via a fluid flow path to a wound dressing and provide negative pressure to the wound dressing. The sensor can be configured to monitor a magnitude or frequency of pressure in the fluid flow path generated by the negative pressure source. The controller can be configured to determine an activity classification, such as breathing, changing positions while lying, sitting, walking, standing, jumping, traversing stairs, leg extending, leg bending, and performing chair squats, based on a change in the magnitude of pressure over time while the negative pressure source maintains the magnitude of pressure in the fluid flow path below a negative pressure threshold. The controller can output an indication of the activity classification.

An overdose of opioids can cause the user to stop breathing, resulting in death. A physiological monitoring system monitors respiration based on oxygen saturation readings from a fingertip pulse oximeter in communication with a smart mobile device and sends opioid monitoring information from the smart mobile device to an opioid overdose monitoring service. The opioid overdose monitoring service notifies a first set of contacts when the opioid monitoring information.

Disclosed are methods and medical device systems for automated delivery of therapies for pain and determination of need for and safety of treatment. In one embodiment, such a medical device system may comprise a sensor configured to sense at least one body signal from a patient; and a medical device configured to receive a first sensed body signal from the sensor; determine a patient pain index based at least in part on said first sensed body signal; determine whether said patient pain index is above at least a first pain index threshold; determine a safety index based at least in part on a second sensed body signal; select a pain treatment regimen based on at least one of said safety index and or a determination that said pain index is above said first pain index threshold; and deliver said pain treatment regimen.

A blood flow stimulator may help encourage blood flow in a limb of a patient. The blood flow stimulator may include a housing configured for sealing about the limb of the patient. The housing may include a sealable volume, and the sealable volume may receive the limb of the patient. The blood flow stimulator may include a seal, and the seal may be coupled with the housing. The seal may engage with at least a portion of the limb, for instance to segregate the sealable volume from a surrounding environment of the blood flow stimulator. The blood flow stimulator may include a conduit extending through the housing. The conduit mat help provide access to the sealable volume, for instance from the surrounding environment. In some examples, an adjustable stent is utilized to enhance blood flow within vasculature of a patient. A stent operator may change a size of the stent.

A bed system with multiple functions includes a frame structure; a plurality of platforms disposed on the frame structure; an adjustable assembly coupled with the frame structure and the plurality of platforms for operably adjusting one or more of the plurality of platforms in desired positions; a plurality of fans mounted onto openings in the plurality of platforms and adapted for operably providing air circulation in a surrounding space of the bed system, and an aromatherapy system attached onto the one or more platforms for producing desired fragrance in the surrounding space so as to promote health and well-being of a user. Each aromatherapy device is configured to produce a fragrance when said aromatherapy device is turned on, and one or more working modes. The fragrance is identical to or different from that produced by other aromatherapy device of the one or more aromatherapy devices.

A method of estimating a parameter indicative of respiratory flow of a patient being administered flow therapy, comprising: optionally administering a gas at a flow rate to the patient using a flow therapy apparatus with a patient interface, determin—-ing a terminal pressure in, at or proximate the outlet of the patient interface or in, at or proximate the nares of the patient, determin -ing nasal RTF, determining a nasal flow parameter being or indicative of nasal flow based on the pressure and a nasal RTF, and optionally outputting the nasal flow parameter or parameter derived therefrom.

Methods, pharmaceutical formulations and devices for the preventative treatment of incidental opioid overdose comprising the intramuscular or subcutaneous administration using an auto-injection device of a pharmaceutical formulation containing the opioid antagonist nalmefene as a prophylactic measure.

A virtual reality and augmented reality system configured for meditation applications including a headset comprising an adjustable strap and a display. The headset further includes heating and cooling elements to provide an immersive virtual reality environment to a wearer. The virtual reality system is operable to determine the physiological condition of the wearer and adjust the virtual reality environment based on the physiological condition of the wearer.