A system and method for altering bone growth on and within an orthopedic implant comprising an implant body, wherein the implant body comprises an exterior surface and an interior surface defining an internal cavity of the implant body, a plurality of electrodes, wherein each electrode is at least partially embedded in the implant body, and comprises at least, a first set of the plurality of electrodes 116, composed of a first material, and a second set of the plurality of electrodes, composed of a second material; and a control system, comprising a processor and circuitry that connects to the plurality of electrodes, wherein the processor, through operating modes, provides machine instructions to control direction and magnitude of current traveling through each electrode from the plurality of electrodes; and a power system, comprising a power source and circuitry that provides electrical power for function of the plurality of electrodes.

An apparatus includes a body configured to be at least partially implanted on or within a recipient and a plurality of electrodes positioned along the body. The plurality of electrodes includes a first set of electrodes configured to apply electrical stimulation signals to at least a portion of the recipient. The plurality of electrodes further includes a second set of electrodes configured to apply an electric field to cell membranes of the recipient, the electric field configured to increase a permeability of the cell membranes to a substance.

An electromagnetic stimulator and iontophoresis device used in treating retina and optical nerve diseases is provided. The electromagnetic stimulator and iontophoresis device enables to reach required threshold values for treating the retina and optical nerve diseases with magnetic fields to eliminate a thermal damage risk formed at a cellular level by cooling cages closed over electromagnetic coils, and allows usage by a patient alone at home, who has low vision, without receiving any professional help by an audio command guidance system including a speaker.

A skin care device according to an embodiment of the present disclosure includes a substrate; a case for covering surface of the substrate; and at least one galvanic current application device electrically connected to the substrate, in which each of the at least one galvanic current application device includes a contact head that forms a contact surface with respect to a user's skin and is electrically connected to the substrate; and a holder provided between the substrate or the case and the contact head, and in which the holder includes an elastic fixing body elastically fixing the contact surface of the contact head to a position spaced apart from the case by a predetermined length.

An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.

A novel electroporation device for the delivery of vaccines that is both effective in generating a protective immune response and tolerable delivery to a subject (or near painless); and also methods of using same device to vaccinate a subject against a variety of infectious diseases and types of cancer in a near painless.

The present invention provides for the intratumoral delivery of at least one immunostimulatory cytokine in combination with at least one checkpoint inhibitor. In particular, it provides delivery of a plasmid encoding the immunostimulatory cytokine using intratumoral electroporation. The checkpoint inhibitor may be administered systemically or encoded on a plasmid and delivered using intratumoral electroporation. The checkpoint inhibitor may be delivered contemporaneously with or after treatment with the immunomodulatory cytokine.

A massage apparatus providing a pulsed electromagnetic field may comprise: a massage unit which comprises a mount frame provided so as to be movable along the body of a user, and an acupressure module protrudingly provided to the mount frame so as to apply pressure to the body of the user; a pulsed electromagnetic field generator which is provided to the mount frame so as to be independent from the acupressure module, and which generates a pulsed electromagnetic field by means of power applied thereto; and a controller which controls the operation of the acupressure module or the generation of the pulsed electromagnetic field. According to such massage apparatus, a pulsed electromagnetic field may be generated by having the pulsed electromagnetic field generator be provided to the massage unit so as to be separate from the acupressure module or air cells performing a massaging operation. In addition, an effect such as body tissue cell activation or damaged cell healing of the pulsed electromagnetic field may be provided when the massaging operation is being performed. Thus, compared to when only a pulsed electromagnetic field is provided without a massaging operation, or when only a continuous electromagnetic field is provided, fatigue of a user may be alleviated, or a disease or illness treatment or prevention effect may be doubled. In addition, since the pulsed electromagnetic field generator is arranged so as to be independent from the acupres sure module or air cells, the range of effects of the electromagnetic field may be expanded so as to include providing a pulsed electromagnetic field to even nearby sites to which pressure is not applied by the acupressure module or air cells, and since the pulsed electromagnetic field generator may be independently detached or replaced, costs for managing the massage apparatus may be reduced.

A massage apparatus providing a pulsed electromagnetic field may comprise: a massage unit which comprises a mount frame provided so as to be movable along the body of a user, and an acupressure module protrudingly provided to the mount frame so as to apply pressure to the body of the user; a pulsed electromagnetic field generator which is provided to the mount frame so as to be independent from the acupressure module, and which generates a pulsed electromagnetic field by means of power applied thereto; and a controller which controls the operation of the acupressure module or the generation of the pulsed electromagnetic field. According to such massage apparatus, a pulsed electromagnetic field may be generated by having the pulsed electromagnetic field generator be provided to the massage unit so as to be separate from the acupressure module or air cells performing a massaging operation. In addition, an effect such as body tissue cell activation or damaged cell healing of the pulsed electromagnetic field may be provided when the massaging operation is being performed. Thus, compared to when only a pulsed electromagnetic field is provided without a massaging operation, or when only a continuous electromagnetic field is provided, fatigue of a user may be alleviated, or a disease or illness treatment or prevention effect may be doubled. In addition, since the pulsed electromagnetic field generator is arranged so as to be independent from the acupres sure module or air cells, the range of effects of the electromagnetic field may be expanded so as to include providing a pulsed electromagnetic field to even nearby sites to which pressure is not applied by the acupressure module or air cells, and since the pulsed electromagnetic field generator may be independently detached or replaced, costs for managing the massage apparatus may be reduced.

A bone growth stimulator includes an antenna configured to receive electromagnetic signals in a radio frequency band, and a controller having a power source including a supercapacitor electrically connected to the antenna. The supercapacitor stores a charge in accordance with the electromagnetic signals received by the antenna. The bone growth stimulator further includes a cathode extending from the controller to a desired location of bone growth and an anode electrically connected to the power source and extending from the controller. Electrical energy travelling from the anode to the cathode stimulates bone growth in a patient.