A system and method of controlling the application of energy to tissue using measurements of impedance are described. The impedance, correlated to the temperature, may be set at a desired level, such as a percentage of initial impedance. The set impedance may be a function of the initial impedance, the size and spacing of the electrodes, the size of a targeted passageway, and so on. The set impedance may then be entered into a PID algorithm or other control loop algorithm in order to extract a power to be applied to a treatment device.

A medical drug devices for transdermal drug delivery systems (TDDS) comprising a novel iontophoretic polymeric microneedle device and its use in administration of drugs.

The disclosure relates to a flexible active species generator comprising: a first electrode of a conductive metal thin film; a second electrode of a ground electrode; a flexible dielectric layer of an insulator formed between the first electrode and the second electrode; and a plasma resistant functional layer formed between the dielectric layer and the second electrode, wherein the first electrode and the second electrode are electrically connected to an external power supply to generate an atmospheric pressure plasma to generate active species. The flexible active species generator has a plasma resistant function to prevent deformation and decomposition of an insulator caused by the plasma as well as an active species generating function from atmospheric pressure plasma, and has durability and safety, which is thus applicable to articles, foods, garments and human body in various forms.

Certain substances (e.g., large molecules) that ordinarily cannot traverse the cell membrane of cells can be introduced into cells by applying an alternating electric field to the cell for a period of time, wherein the frequency of the alternating electric field is selected so that application of the alternating electric field increases permeability of the cell membrane. Once the permeability of the cell membrane has been increased, the substance is able to cross the cell membrane. This approach is particularly useful in the context of cancer cells (e.g., glioblastoma).

A method for using beauty instrument with mask is provided. The method comprises providing a beauty instrument with mask comprising a flexible mask and a controller, applying the flexible mask of on a user's face, and turning on the controller and selecting a function button on the controller, inputting a current to a plurality of functional layers in the flexible mask, and stimulating face skin with the current.

A body physiotherapy machine contains a conductive sphere member and a body configured to output electric physiotherapy energy to the conductive sphere member. The conductive sphere member is held by a user to contact his/her discomfort or acupuncture points so as to comfort the user and to enhance metabolism by ways of the electric physiotherapy energy, thus maintaining health easily.

A skin treatment device is provided with a thermally modulated treatment head adapted for contact with a user or other subject's skin. The device includes one or more thermal elements adapted to modulate the temperature of the head, a power source adapted to provide current to the thermal elements, and a controller adapted to modulate the head temperature by controlling the current delivered to the thermal elements. A topical agent can be disposed between the treatment head and the subject's skin, where the temperature of the topical agent is modulated in response to the temperature thereof.

The invention relates to a device for generating electrical, magnetic, and/or electromagnetic signals, which, at different treatment frequencies, can be used to treat the human body, an electronic noise element (22) being provided as a means for providing a noise signal, which noise signal can be used for the selection of a treatment frequency, the properties of which electronic noise element are at least partly dependent on at least one biophysical radiation emission of the human body.

It is provided a method and device for delivering transdermally a molecule non-invasively to a subject comprising irreversibly electroporating a region of the skin.

The systems and methods of this disclosure are directed to the treatment of disease states, and particularly different types of cancer, by application of low energy emission therapy. The device and method provide treatments of disease states in a patient, and particularly of cancer types, by the application to the patient of particular and disease-specific low energy high frequency radiation. The device uses a high precision frequency synthesizer to generate radio frequency radiation that is amplitude-modulated at identified tumor-specific frequencies for application to the patient during therapy.