A system for the surface and subsurface delivery of therapeutic and cosmetic agents. The system includes a disposable attachable tip that can be pre-filled with medications or cosmetics and attached to hand pieces including electromagnetic and mechanical energy hand piece devices.

Systems and methods for restructure and stabilization of bones that provide an anti-microbial effect are disclosed herein. A device includes a delivery catheter having an inner void for passing at least one light sensitive liquid, and an inner lumen; an expandable member releasably engaging the distal end of the delivery catheter; at least one channel positioned in the expandable member; and a light conducting fiber sized to pass through the inner lumen of the delivery catheter and into the expandable member, wherein, when the light conducting fiber is in the at least one channel, the light conducting fiber is able to disperse light energy to provide an anti-microbial effect. When the light conducting fiber is in the expandable member, the light conducting fiber is able to disperse the light energy to initiate hardening of the light sensitive liquid within the expandable member to form a photodynamic implant.

An osseointegrated fixture of a percutaneous osseointegrated prosthesis (POPs) anchors directly into a bone of a residual limb within an amputation stump. By anchoring directly into the bone, the POPs provides improved mobility, comfort, and function for an amputee, but an interface between an opening in the skin and the osseointegrated fixture, which allows the anchoring directly into the bone, is prone to infection by microbes. An anti-microbial device can be attached to and/or embedded within an extracorporeal portion of the osseointegrated fixture to irradiate at least a portion on the interface with at least one wavelength of light selected for its antimicrobial effects.

The present invention relates to a light treatment apparatus and a method of controlling the same, and provides to a light treatment apparatus and a method of controlling the same, including: a treatment light irradiating unit for irradiating a treatment region with treatment light a plurality of times while moving on the treatment region; a sensing unit for detecting movement information of the treatment light irradiating unit; and a control unit for controlling an irradiation pattern of the treatment light based on the detected movement information such that an irradiation area of the treatment light to be irradiated from the treatment light irradiating unit overlaps at least in part with an irradiation area of the treatment light which is previously irradiated.

Systems and methods for treating a fibrous mass associated with a condition such as Morton's neuroma, plantar firbroma, or Achilles tendinopathy are disclosed. According to illustrative implementations, exemplary methods may comprise identifying a location of the fibrous mass and non-surgically delivering electromagnetic energy to the fibrous mass.

An apparatus comprises a flexible substrate, a phased array antenna system disposed on the substrate, and a wearable applicator. The flexible substrate is configured to conform to a shape corresponding to a portion of a human body. The phased array antenna system comprises a plurality of antenna elements configured to resonate in response to an input signal and to generate a collective output electromagnetic pattern to propagate wirelessly to a target region in a human body. The wearable applicator is configured to align the collective output electromagnetic pattern with the target region.

Embodiments disclosed include systems, methods, and apparatuses, directed to administering thermal neural modulation to mammalian tissue to control nerve conduction. Embodiments disclosed include an apparatus comprising a thermal energy source, a first heat exchanger coupled to the thermal energy source and configured to receive thermal energy therefrom, a thermal applicator configured to be disposed and secured to the anatomy of a subject having a nerve therein, in contact with the skin on the anatomy and overlying a treatment portion of the nerve, the thermal applicator configured to transfer thermal energy to the skin to raise the temperature of the treatment portion of the nerve above a physiologic temperature, a second heat exchanger is coupled to the thermal applicator and configured to transfer thermal energy thereto, and a fluid conduit having a first portion coupled to the first heat exchanger and a second portion coupled to the second heat exchanger. The fluid conduit is configured to have fluid circulated therethrough to convey thermal energy from the thermal energy source via the first heat exchanger and to the thermal applicator via the second energy at a temperature.

A method of delivering light energy to a pathological tissue includes emitting light energy from a first optical element within a cannula, producing a substantially uniform irradiance profile from the light energy within the cannula, transmitting the light energy emitted from the first optical element through a second optical element in thermal contact with a distal end of the cannula to the pathological tissue without ablating the pathological tissue, and conducting thermal energy from the pathological tissue through the second optical element and to the cannula.

A multifunctional skin patch can be used during a treatment procedure to achieve one or more safety factors, including skin cooling, pain management, laser plume control, and/or proper application of the treatment. The multifunctional skin patch includes a transparent hydrogel layer that can be applied to a patient's skin prior to application of the treatment procedure. The treatment procedure can be conducted through the transparent hydrogel layer, and the transparent hydrogel layer (with can be pre-cooled) can cool and/or control pain within the portion of the patient's skin during and/or after the treatment procedure. In some instances, the multifunctional skin patch can also include a transparent indicator layer (covering at least a portion of the transparent hydrogel layer) with dispersed indicator particles attached thereto and/or embedded within. The indicator particles are configured to change in appearance upon application of treatment procedure through the transparent indicator layer.

Dermatological systems and methods for providing a therapeutic laser treatment wherein the duration of a therapeutic laser pulse is based on one or more determinations of a surface temperature of the skin during the delivery of the pulse. Initiation of the therapeutic laser pulse may be based on sensed skin temperature during a cooling of the skin prior to initiation of the pulse.