A skin imaging and diagnostic method and apparatus comprising, a frame, configured to circumscribe a target tissue on the skin of a patient. An electro-optics unit of the apparatus comprising: an illuminator assembly comprising illuminating elements, configured to provide illumination light on the target tissue; an imaging optics assembly; and an image sensor assembly, comprising an image sensor, wherein the imaging optics assembly is configured to collect backscattered said illumination light from the target tissue and focus the collected backscattered illumination light on the image sensor; and the image sensor is disposed to consequently sense an image of the target tissue. A controller configured to activate illuminating elements and to capture each image from the image sensor.

The present disclosure provides a method for treating ischemic stroke by illuminating a skin surface to reduce free radical generation in subsurface target tissues (e.g., the brain following an ischemic event). The method utilizes a waveguide that receives light from a light source. The waveguide is placed adjacent a skin surface of a patient and the waveguide emits light that passes through the skin surface and illuminates a subsurface target tissue. The waveguide includes light-extracting features configured to emit light at a target angle relative to the surface tissue. That is, the light-extracting features alter a trajectory of light emitted by the waveguide, such that a larger percentage of light emitted by the light guide has an angle that is +/−25 degrees off of a center line of the light guide.

Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.

The technology disclosed herein relates to a transcutaneous irradiation device having a top portion and a bottom portion. The top portion may include one or more transcutaneous irradiation modules configured to be arranged on a head of a user, the top transcutaneous irradiation modules including a top pulsed laser source. The bottom portion may include one or more transcutaneous irradiation modules configured to be arranged on an abdomen of the user, the top transcutaneous irradiation modules including a bottom pulsed laser source. A modulation frequency may be applied to the top and bottom irradiation modules such that the top and bottom pulse laser sources are subjected to a double pulse.

Systems and methods are described for treatment of neurological conditions in which transcranial illumination using infrared, near-infrared and/or red wavelengths of light are delivered into the brain of a patient using a portable head wearable device. Arrays of light emitters are simultaneously controlled to provide a selected power density and distribution during a therapeutic session to treat a condition of the patient. An external controller such as a touchscreen tablet or laptop computer can be used to select illumination parameters for each patient. The system can be used to provide treatment to children such as those having autism spectrum disorder (ASD).

A safety monitoring and management system for phototherapy machine, comprising: a cabin, the inside space is enough to containing a user body, at least one infrared light source arranged inside the cabin, using the thermal radiation energy generated by the infrared light source to irradiate the human body inside the cabin; a peripheral console is set around the phototherapy machine; a monitoring and management platform arranged at a position far from the phototherapy machine and the peripheral console; an online data integration system receives the information uploaded by the peripheral console or the monitoring and management platform through the Internet, for the user to adjust the parameter of the infrared light therapy by himself.

A device, for vision training and therapy, comprises a spectacle frame including a left rim, a right rim, and a bridge connecting the left rim and the right rim, wherein the left rim and the right rim include a plurality of therapeutic light sources located along the left rim and the right rim, for providing light therapy to the eyes of a user, a longitudinal member connected with the spectacle frame, and extending away from the spectacle frame, along the line of sight of the user, wherein the longitudinal member includes a plurality of colored light sources connected by a white stripe arranged to be viewable by both eyes of the user and a controller connected with the plurality of therapeutic light sources and the plurality of colored light sources. Further, the longitudinal member is extendible through an extension mechanism attached to the spectacle frame.

A device for eradicating at least one pathogen in a nasal passage of a human or animal may include a housing configured to be inserted into the nasal passage, at least one radiation source, configured to emit radiation, coupled to the housing such that at least a portion of a radiation emitting surface, upon insertion of the housing into the nasal passage, faces at least a portion of nasal lining of the nasal passage, and an electrical circuit carried by the housing and electrically connected to the at least one radiation source, the electrical circuit including at least one circuit component for controlling the at least one radiation source to emit the radiation to irradiate the nasal passage, the emitted radiation having a frequency or range of frequencies at which the at least one pathogen in the nasal passage, when irradiated by the emitted radiation, is eradicated.

The invention relates to a device for generating electrical, magnetic, and/or electromagnetic signals, which, at different treatment frequencies, can be used to treat the human body, an electronic noise element (22) being provided as a means for providing a noise signal, which noise signal can be used for the selection of a treatment frequency, the properties of which electronic noise element are at least partly dependent on at least one biophysical radiation emission of the human body.

A light irradiation device includes a first light source emitting first light in a visible wavelength band and a second light source emitting second light, in which at least part of a wavelength band is different from a wavelength band of the first light source and which catalyzes synthesis of a functional substance in a target to which light is applied. The second light includes light in a wavelength band of ultraviolet B.