In one or more embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein.

Systems, devices and methods that facilitate safe heating of eyelids to treat dry eye are disclosed. According to one embodiment, an apparatus for optical heating of an eyelid of a patient includes: a housing configured to be grasped by a human hand; at least one light emitter coupled to the housing and configured to emit beams of infrared light; a waveguide component coupled to the at least one light emitter and configured to direct the beams of light toward the eyelid; and a scleral cover configured to couple to the housing, the scleral cover comprising: a curved protective portion configured to reflect infrared light emanating from the at least one light emitter.

An apparatus is provided. The apparatus includes a flexible wrap and a plurality of lights arranged on the wrap. The wrap is configured to wrap around a body of a user such that the lights face selected areas of the body. The apparatus is configured to cause the lights to emit light at a first predetermined wavelength to the selected areas of the body that is sufficient to perforate one or more fat cells at the selected areas of the body to drain the content within the one or more fat cells when power is supplied to the lights. The apparatus is configured to cause the lights to emit light at a second predetermined wavelength to the selected areas of the body at the same time as the lights emit light at the first predetermined wavelength when power is supplied to the lights.

A surgical device such as a therapy device that can allow a surgeon to treat a target tissue with ultra-violet (UV) light ablation therapy. In one example, the therapy device is configured to treat menorrhagia. In that instance, the therapy device may be configured to effect or destroy the endometrium during a procedure treating menorrhagia.

A method for noninvasive treatment of diabetic retinopathy helps prevent and reverses diabetic retinopathy and other vascular retinopathies, such as diabetic macular edema for a patient. The method comprises administering at least 80 percent pure oxygen to a patient in an oxygen chamber or nasal cannula. The oxygen chamber includes light emitting diodes that emit a light having a wavelength between 630-700 nm wavelengths on the patient. The method also includes administering an anti-inflammatory agent; an anti-oxidant; at least one of the following: an amino acid, arginine, and citrulline; and an omega-3 fatty acids to the patient. In extreme cases of diabetic retinopathy, a cold laser therapy is also administered to the patient with a wavelength between 570 nanometers and 1000 nanometers. The combination of all the aforementioned treatment modalities and compositions that work to synergistically to achieve unexpected clinical results for prevention and reversal of diabetic retinopathy.

An instrument for therapeutically cytotoxically ablating parathyroidal tissue is disclosed. A substance is capable of transforming the parathyroid gland from overproduction of parathyroid hormone when the substance's quantity exceeds a set amount, and is capable of transforming the parathyroid gland from overproduction only when activated by application of sufficient units of an electromagnetic energy having a frequency ranging from 400 THz to 30 PHz when the substance's quantity is below the set amount. A delivery device is operable to introduce the substance into the parathyroidal tissue and to quantitatively limit the quantity to below the set amount. An energy device is operable to apply units of the electromagnetic energy after the substance has been introduced. A sensor is operable to monitor the activation of the substance as the electromagnetic energy is applied. The energy device is further operable to modulate applying the electromagnetic energy when the substance has been activated.

Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects.

Nasal colonisation with pathogenic bacteria continues to present challenges for patients undergoing surgical procedures, and the physicans that treat them. Many physicians and scientists have discussed different ways to improve nasal decolonization in the last 100 years. Various embodiments include a medical kit composed of items specifically tailored to assist in the photo-biologic eradication of bacteria in the human nares.

An ophthalmic stimulator for temporarily constricting a pupil of art eye comprises a mobile irradiation control system, to generate an irradiation control signal; an irradiation source, coupled to the irradiation control system, to generate an irradiation; and an irradiation delivery system, coupled to the mobile irradiation control system, to receive the irradiation from the irradiation source, and to deliver a patterned irradiation to an iris of the eye; wherein the mobile irradiation control system controls at least one of the irradiation source and the irradiation delivery system with the irradiation control signal so that the patterned irradiation causes a temporary constriction of the pupil of the eye, without causing a permanent constriction of the pupil.

An instrument for therapeutically cytotoxically ablating parathyroidal tissue is disclosed. A substance delivery device with which a quantity of an activator substance that is less than a cytotoxic ablation quantity threshold of a parathyroid gland can be percutaneously introduced into parathyroidal tissue is provided. The activator substance, when introduced, is not activated. An energy source device that includes a selector with which a quantity of an energy that is less than a cytotoxic ablation energy threshold of the parathyroid gland can be selected and an energy production device operable to apply the energy to the activator substance is provided. The activator substance, when introduced, and the energy indicated, when applied to the introduced activator substance, are in combination capable of cytotoxically ablating the parathyroid tissue and transforming the parathyroid gland from overproduction to non-overproduction of the parathyroid hormone in a manner that maintains non-parathyroidal tissue functions and is non-lethal.