A controller (30) of this light irradiation device (100) is configured to control a plurality of light guide members (20) connected to a plurality of light output ports, respectively, in an identifiable manner by causing the identification light (90) to be emitted from each of the plurality of light output ports (12).

A phototherapy device is provided for delivering targeted phototherapy to an oral cavity. The phototherapy device includes a main body configured to be received within the oral cavity, a light source for emitting light, and an air gap located between the light source and a shell for improved light delivery to the pharyngeal tissues of the oral cavity.

Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter. LED lighting systems, methods, and devices can switch between a daytime configuration and a night time configuration, wherein the daytime configuration provides unfiltered light and the night time configuration provides filtered light.

The invention relates generally to intradermal, transdermal, and/or transmembrane delivery of biologically active substances in the epidermis and/or through the skin, sub-dermal tissues, blood vessels and cellular membranes without causing damage to the cellular surface, tissue or membrane. The biologically active substances may have a molecular weight no less than about 5.8 kDa to about 2,500 kDa, such as Hyaluronic Acid (HA). The biologically active substances may be deposited in a dermal patch containing a red algae polysaccharide-based matrix, wherein the red algae poly-saccharide is an extract of Chondrus crispus at 2% by weight of the dermal patch. The invention provides systems and methods for enhanced intradermal, transdermal, and/or transmembrane delivery of such biologically active substances using pulsed incoherent light. The invention further provides a device for the application of the pulsed incoherent light to cellular surfaces and membranes using those compositions and methods.

The present method and apparatus seek to provide cosmetic skin care including application in concert or consecutively of various types of energy to bring about a welcomed combination of skin cleansing and skin rejuvenation and enhancing. There is thus provided, in accordance with an exemplary embodiment of the current method and apparatus an apparatus for cosmetic skin care including a brush-like head having a multiplicity of bristles attached to one or more carriers at least a portion of which is operative to apply forms of energy to the skin. At least one of the forms of energy is RF energy while other forms include light energy, mechanical energy, ultrasound energy and any suitable combination thereof.

A disinfection device may include a housing having a concave shape, a light source coupled to the housing, where the light source provides light configured to disinfect a surface, a contact sensor coupled to the housing, where the contact sensor is configured to detect contact with a body of a user.

Provided are systems and miniature devices configured to navigate within a patient to a location therewithin for delivering to induce a localized therapeutic effect, such as the delivery of catalyzing energy and/or for the conversion of a prodrug to a pharmaceutically active drug. Further provided are various methods of treatment using such systems and devices.

The embodiments herein provide a method for producing activated carbonaceous balls. The method includes a step of crushing and sizing raw coconut shells to form coconut shell granules having a diameter of about 0.02 mm-2.36 mm, preferably 0.075 mm-1.18 mm. The method includes a step of mixing pure water to a food grade powder appropriately and boiling it slowly at 15 C.-80 C. to obtain a water-food grade powder mixture. The method includes a step of adding the water-food grade powder mixture 20-40% by weight to the coconut shell granules 100% by weight to obtain a slurry in a pourability condition. The method includes a step of pouring the slurry into a pill making machine equipped with a mold of 3 mm, 5 mm, and 8 mm in diameters selectively to produce the spherical carbon tablets. The method includes a step of drying the spherical carbon tablets and carbonizing the spherical carbon tablets to obtain the activated carbonaceous balls.

A method for generating light intensity inside a tumor to aid in the treatment of diseases such as cancer is disclosed. The light is generated inside the body to perform a modified photodynamic therapy treatment (PDT) that allows treatment of body regions that are inaccessible by normal PDT procedures. In addition, the use of two spatially and temporally coincident treatment modalities, i.e. radiation and PDT, have the potential for significant biological synergy in the tumor.

Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter. LED lighting systems, methods, and devices can switch between a daytime configuration and a night time configuration, wherein the daytime configuration provides unfiltered light and the night time configuration provides filtered light.