Presented systems and methods facilitate efficient and effective generation and delivery of radiation. In one embodiment, a radiation generation component includes a high intensity target that produces Bremsstrahlung radiation in response to impacts by charged particles, wherein the high intensity target is configured with operating limitations based primarily on catastrophic failure mechanisms rather than fatigue failure mechanisms. The high intensity target is configured to be compatible with a loading system of a radiation generation system. The high intensity target can have a catastrophic failure strain percentage in the range of 0.5 to 4.0 percent. The catastrophic failure mechanisms can include at least one selected from the group comprising ultimate tensile strength, fracture strain, and melting point. The high intensity target can have a product life in a low cycle fatigue regime range. The high intensity target can comprise a material with a melting temperature in the range of 800 C to 3,700 C. The high intensity target can be configured to load in an accelerator enclosure. The high intensity target can include an identification feature. Th e Bremsstrahlung radiation can correspond to average dose rates greater than 1.0 greys per second (Gy/s).

Provided is a method for determining a rotation speed of a gantry. The method includes: acquiring control information of the gantry, wherein the control information of the gantry includes: leaf information and dose information of control points; determining the rotation speed of the gantry and dose rates at the control points based on the leaf information and the dose information of the control points; and adjusting the rotation speed of the gantry based on the dose rates at the control points and a maximum equipment dose rate.

Disclosed herein are cancer treatment methods.

A particle therapy system includes: an accelerator that accelerates a particle beam; an irradiation system that applies the beam accelerated by the accelerator to a target; and a controller that controls the accelerator and the irradiation system. The controller has a treatment execution system that generates a control parameter which controls the accelerator and the irradiation system based on a treatment plan and has a treatment execution controller that controls the accelerator and the irradiation system based on the control parameter generated by the treatment execution system. When irradiation to the target by the irradiation system is suspended due to a failure or an artificial manipulation, the treatment execution system calculates an irradiated dose of the particle beam and an unirradiated dose of the particle beam, and the treatment execution system delivers at least the unirradiated dose to the treatment execution controller.

The invention provides a charged particle irradiation apparatus including: a collimator apparatus provided in an irradiation nozzle that emits a charged particle beam to an irradiation target; and a collimator control unit that controls the collimator apparatus. The collimator apparatus includes a collimator mechanism having one or more arm-shape collimators extending from a base part and a drive mechanism that moves the collimator mechanism on a plane perpendicular to a traveling direction of a charged particle beam. The arm-shape collimator includes one or more movable leaves that rotate independently of each other on the perpendicular plane. By moving the collimator mechanism and/or rotating the movable leaves so that the arm-shape collimators are arranged along a shape of an edge of an irradiation target on the perpendicular plane, the collimator control unit causes the arm-shape collimators to block a charged particle beam that would otherwise irradiate outside of the edge of the irradiation target.

Disclosed herein are radiotherapy systems and methods that can display a workflow-oriented graphical user interface(s). In an embodiment, a system comprises a radiotherapy machine comprising: a couch; and a gantry having a camera in communication with a server, wherein the server is configured to: present for display, in real time on a screen associated with the radiotherapy machine, images received from the camera, wherein when the gantry changes its orientation, the camera revises at least one of its orientations, such that images transmitted to the server maintain an original orientation.

A method for driving a leaf of a multi-leaf collimator (MLC) mounted on a collimator that is mounted on a gantry is provided. The method may include obtaining an electrical current of an actuator of the leaf; generating a target control signal based on the electrical current of the actuator; and causing a drive circuit to generate a driving signal for driving the leaf to move by providing the target control signal to the drive circuit.

The present disclosure relates to systems and methods for pulse parameter modulation. The systems may perform the methods to obtain information related to a treatment plan; determine a backward window based on the information related to the treatment plan, within which one or more radiation pulses have been transmitted; determine backward information associated with the backward window based on the information related to the treatment plan and the backward window; determine a forward window based on the information related to the treatment plan, within which one or more radiation pulses are to be transmitted; determine forward information associated with the forward window based on the information related to the treatment plan, the backward information, and the forward window; and determine one or more pulse parameters of the forward window based on the forward information.

A radiotherapy treatment planning method for achieving a FLASH radiotherapy treatment plan involves optimizing the plan using an optimization problem that has been designed to maximize the part of the irradiation that will be delivered under FLASH conditions, in particular to an organ at risk, to minimize the damage to the organ at risk.

Disclosed are a neutron capture therapy device and an operation method of a monitoring system. The neutron capture therapy device includes a neutron beam irradiation system, a detection system and the monitoring system. The neutron beam irradiation system generates a neutron beam for performing neutron irradiation therapy on a sick body. The detection system is used for detecting irradiation parameters during a neutron beam irradiation therapy, and the monitoring system is used for controlling the whole neutron beam irradiation process. The monitoring system includes a storage part for storing the irradiation parameters, a control part for executing a therapy plan according to the irradiation parameters stored in the storage part, and a correction part for correcting part of the irradiation parameters stored in the storage part. The disclosure improves the accuracy of the dosage of the neutron beam for irradiating the sick body.