A method for performing deep tissue stimulation using radiation-enabled optogenetics including introducing a plurality of nanoscintillators into a region with light sensitive cells, and targeting the nanoscintillators with a primary radiation to cause the nanoscintillators to emit optical energy. The light sensitive cells having an optically active wavelength range, and the emitted optical energy having a wavelength in the optically active wavelength range. In particular, introducing X-ray excited optical luminescent nanomaterials to a tissue region and controlling electrical activity in cells containing opsins.

An interstitial source including a base suitable for implanting in a tumor and alpha emitting atoms attached to the base, with a concentration of at least 6 Ci per centimeter length. The alpha emitting atoms are attached to the base, with a desorption probability upon radioactive decay of not more than 30%.

Provided is a neutron beam transmission adjusting device including a neutron beam transmission unit including a neutron reactant and capable of modulating the energy and/or the flux of a neutron beam transmitted through the neutron beam transmission unit.

Presented systems and methods facilitate efficient and effective monitoring of particle beams. In some embodiments, a radiation gun system comprises: a particle beam gun that generates a particle beam, and a gun control component that controls the gun particle beam generation characteristics, including particle beam fidelity characteristics. The particle beam characteristics can be compatible with FLASH radiation therapy. Resolution control of the particle beam generation can enable dose delivery at an intra-pulse level and micro-bunch level. The micro-bunch can include individual bunches per each 3 GHz RF cycle within the 5 to 15 sec pulse-width. The FLASH radiation therapy dose delivery can have a bunch level resolution of approximately 4.410{circumflex over ()}6cGy/bunch.

A quality control device which enables all the routine quality controls of linear particle accelerators (LINACs), which are used in radiation oncology, to be performed automatically.

The present disclosure provides a radiation therapy device and system. The radiation therapy device includes a first treatment head and a second treatment head. A beam emitted from the second treatment head intersects with a beam emitted from the first treatment head at an intersection point. The first treatment head is an X-ray treatment head, and the second treatment head is an X-ray treatment head, a multi-source focusing treatment head, or an intensity-modulated treatment head. The radiation therapy device may increase a dose rate at the intersection point.

Presented systems and methods facilitate efficient and effective monitoring of particle beams. In some embodiments, a radiation gun system comprises: a particle beam gun that generates a particle beam, and a gun control component that controls the gun particle beam generation characteristics, including particle beam fidelity characteristics. The particle beam characteristics can be compatible with FLASH radiation therapy. Resolution control of the particle beam generation can enable dose delivery at an intra-pulse level and micro-bunch level. The micro-bunch can include individual bunches per each 3 GHz RF cycle within the 5 to 15 sec pulse-width. The FLASH radiation therapy dose delivery can have a bunch level resolution of approximately 4.410{circumflex over ()}6cGy/bunch.

The present disclosure provides a neutron capture therapy system, including an accelerator for generating a charged particle beam, a neutron generator for generating a neutron beam having neutrons after irradiation by the charged particle beam, and a beam shaping assembly for shaping the neutron beam. The beam shaping assembly includes a moderator and a reflecting assembly surrounding the moderator. The neutron generator generates the neutrons after irradiation by the charged particle beam. The moderator moderates the neutrons generated by the neutron generator to a preset energy spectrum. The reflecting assembly includes a reflecting assembly to deflected neutrons back to the neutron beam and a supporting member to support the reflectors. A lead-antimony alloy is for the reflecting assembly to mitigate a creep effect that occurs when only a lead material is for the reflectors, thereby improving the structural strength of a beam shaping assembly.

A radiation dosage monitoring system comprising a 3D camera operable to obtain images of a patient undergoing radiation treatment, the 3D camera being operable to detect Cherenkov radiation and any subsequent secondary and scattered radiation originating due the initial Cherenkov radiation emitted from a surface of the patient when the patient is irradiated by a radiation beam; and a processing module operable to process the images obtained by the 3D camera utilizing data indicative of chromophores present in a patient's skin to apply a correction factor to such images to account for absorption of Cherenkov radiation by chromophores in the skin when utilizing the images to generate a representation of radiation applied to the surface of the patient.

An x-ray imaging apparatus and associated methods are provided to process projection data from an offset detector during a helical scan, including view completion. The detector may be offset in the channel and/or axial direction. Projection data measured from a current view is combined with projection data measured from at least one conjugate view to reconstruct a target image. A two-dimensional aperture weighting scheme is used to address data redundancy.