A retainer, system and method of tattoo removal including treating a tattooed region of skin with an oxidizing or bleaching solution activated by certain wavelengths of light may be provided. The method of tattoo removal may include applying a layer of removal solution to a tattooed region of skin; regulating a temperature of the layer of removal solution with a temperature control element; and exposing the layer of removal solution to a light source of pre-determined wavelength. Light of certain wavelengths may improve or supercharge the effects of certain pharmaceuticals or target chemicals and agents, creating a synergistic effect that may break down tattoo ink molecules and eliminate the appearance of tattoos in the skin of humans or other animals.

The present invention provides a method for removing a tattoo in a region of skin the method comprises administering to a least a portion of the tattoo, and a composition comprising an effective amount of a bisphosphonate and at least one pharmaceutically acceptable excipient to at least cause fading of the tattoo in said region.

A treatment system and method includes use of a chemical facilitator to provide a result-effective event against one or more negative therapeutic effects related to exposing to a light output a skin portion including a condition treatable in whole or in part with light. In one exemplary embodiment for skin treatment including tattoo removal, perfluorodecalin is used to inhibit or resolve whitening, for example to speed a laser therapy session.

An improved erasable tattoo ink and a method and apparatus for removing tattoos using an energy transfer photodisruptive mechanism whereby efficiency of the transfer of energy from a low energy light source to a higher energy donor and then to a tattoo pigment molecule for photodecomposition of the ink color pigmentation is optimized.

The present invention provides a method for removing a tattoo in a region of skin the method comprises administering to a least a portion of the tattoo a composition comprising an effective amount of a bisphosphonate and at least one pharmaceutically acceptable excipient to at least cause fading of the tattoo in said region.