The invention relates methods of reducing the risk or preventing the occurrence of an adverse event (AE) or a serious adverse event (SAE) associated with a medical treatment comprising inhalation of nitric oxide.

Pressurized gas bottles with integrated valves, in which a plurality of functional supports are integrated in an extraction unit, are equipped with complex fall protection means. Moreover, in such a valve, a new approval procedure is carried out for the entire valve in the event of multiple modifications, for example when supplementing it with an additional function. In order to reduce the effort associated with this, an extraction fitting for a pressurized gas bottle is provided with a modular design, wherein a base module comprising the shut-off member and a fall protection device securing the shut-off member complies with legal requirements regarding fall protection and the shut-off device of the pressurized gas bottle. All further functionalities of the extraction fitting are integrated in at least one additional module, which is connected to the base module in a fixed but removable manner and without impairing the fall safety.

To provide a method for stably storing tetrafluoropropene filled in a container for e.g. storage or transportation, without occurrence of reaction such as polymerization.

A method for storing tetrafluoropropene in a gaseous-liquid state composed of a gas phase and a liquid phase in a closed container, wherein the oxygen concentration (content) in the above gas phase is adjusted to at least 3 vol ppm and less than 3,000 vol ppm at a temperature of 25 C.

A system and method is disclosed for storing a fluid in a storage vessel in liquefied form and delivering it in gaseous form to an end user through a supply line. The system comprises a pressure relief circuit for returning the fluid from the supply line to the vessel when predetermined conditions are met. The pressure relief circuit comprises a return line connected to the supply line and the storage vessel, a diversion line to divert the fluid elsewhere and a switching device operable to direct the fluid to either one of the lines, as a function of predetermined conditions.

A simulated smoking device (1) comprising a simulated cigarette having a substantially cylindrical cigarette-like shape and a refill device (2, 50) having a substantially cuboid housing with a cigarette pack-like shape containing refill gas (32, 59) for the simulated cigarette and having means for selectively retaining the simulated cigarette. The simulated cigarette may be retained wholly within the housing. It may be retained at a location different from the refill location. A dose counter may be provided to give a visual indication of the doses in the refill device.

The invention relates to a container/container support assembly, notably for a medical gas cylinder, comprising a gas container (11) comprising a protective cap (3) comprising a peripheral wall (3), and a container support (20) able and designed to accept and bear said gas container (11). The protective cap (3) of the gas container (11) comprises a fixing element (10) projecting from the surface of the peripheral wall (3), and said container support (20) comprises an attachment system (24) for fixing said container support (20) to a bearing structure (30), and a housing (22) able and designed to accept said fixing element (10) borne by the protective cap (3) of the gas container (11) so as to secure said gas container (11) to said container support (20) when said fixing element (10) is positioned in said housing (22) of the container support (20).

Devices, systems, and methods for pressure-regulated melting are disclosed. A vessel includes a solids inlet, a fluids outlet, a cavity, and a warm fluids inlet. Solids enter the vessel through the solids inlet. The cavity has an internal pressure. Warm fluids enter the vessel through the warm fluids inlet. The warm liquid being directed into the vessel provides an inlet pressure that produces a backpressure in the solids inlet. A feed rate of the warm liquid is matched to a feed rate of the solids such that the solids are melted directly to a product liquid at the internal pressure. The product liquid is passed out of the vessel through a restriction that maintains the internal pressure in the cavity.

A cylinder valve for use with a cylinder containing fluid under pressure. The cylinder valve has an aluminum valve body. The valve body has a flow passage extending through the valve body for permitting fluid to flow through the body to exit the cylinder and a vent passage for permitting fluid to vent from the cylinder. Nickel plating is applied to the vent passage. A dispensing valve is positioned along the flow passage. Thermal relief material in the vent passage blocks flow through the vent passage until a predetermined venting temperature is reached when the material changes to a flowable state to unblock the vent passage and allow venting of the cylinder through the vent passage.

To provide a method for stably storing tetrafluoropropene filled in a container for e.g. storage or transportation, without occurrence of reaction such as polymerization. A method for storing tetrafluoropropene in a gaseous-liquid state composed of a gas phase and a liquid phase in a closed container, wherein the oxygen concentration (content) in the above gas phase is adjusted to at least 3 vol ppm and less than 3,000 vol ppm at a temperature of 25 C.

Pressure balancing apparatuses and methods disclosed here include embodiments with a waterproof enclosure having walls surrounding an interior chamber, a mounting interface mounted to the enclosure with a port to an outside, and a balancing module, connected to the mounting interface, the balancing module including, a balancing module housing, a valve actuator member inside the balancing module housing, with a receptacle for a pressure source. In certain embodiments the valve actuator member is configured to move in response to changes in differential pressure between a pressure in the enclosure chamber and pressure from the outside, and a module valve, inside the balancing module housing, connected to the valve actuator member, and fluidically separating the enclosure chamber from the port to the outside, wherein the module valve is configured to open and close in response to the movement of the valve actuator member.