Proposed is a method for complex culture of Innotus obliquus, Phellinus linteus, and Ganoderma lucidum. The cultured mycelium complex prepared by the above method has a high content of beta-glucan, which has excellent health functionality and can be used as additives or cooking seasonings for various foods. In addition, when raw meat is salted using the cultured mycelium complex, meat dishes with good taste and flavor can be easily prepared.

Disclosed herein is a composition for enhancing skin elasticity or improving skin wrinkles. In one aspect, 2-isopropylmalic acid or a salt, hydrate or solvate thereof, which is an active ingredient of the present disclosure, activates skin primary cilia and inhibits the expression of MMP-1 to enhance skin elasticity and improve skin wrinkles. In addition, in one aspect, 2-isopropylmalic acid or a salt, hydrate or solvate thereof, which is an active ingredient of the present disclosure, is a safe material and has the advantage that it can be treated in the living body in various forms such as cosmetics and food.

The present invention provides nutritional supplements comprising alginate, in combination with pectin, which will form hydrogels in the stomach when exposed to the low pH of the gastric juice. The formation of a hydrogel will lead to delayed release of sugars and other active ingredients in the stomach. The nutritional supplements can comprise high concentrations of sugars and complex carbohydrates without causing unwanted gastrointestinal symptoms.

The present invention provides nutritional supplements comprising alginate, in combination with pectin, which will form hydrogels in the stomach when exposed to the low pH of the gastric juice. The formation of a hydrogel will lead to delayed release of sugars and other active ingredients in the stomach. The nutritional supplements can comprise high concentrations of sugars and complex carbohydrates without causing unwanted gastrointestinal symptoms.

Glycerol may be placed into liquid form and consumed as a pre-workout or pump product to increase hydration during exercise. Liquid-based glycerol products may embrace the hygroscopic properties associated with glycerol by delivering glycerol in a liquid form that is more compatible and complementary to these physical properties. A liquid suspension of a glycerol-based product may overcome the hygroscopic disadvantages experienced with glycerol when provided in a powder form, chiefly poor mixing, instability during storage, shipping or packaging, as well as dosing limitations.

Glycerol may be placed into liquid form and consumed as a pre-workout or pump product to increase hydration during exercise. Liquid-based glycerol products may embrace the hygroscopic properties associated with glycerol by delivering glycerol in a liquid form that is more compatible and complementary to these physical properties. A liquid suspension of a glycerol-based product may overcome the hygroscopic disadvantages experienced with glycerol when provided in a powder form, chiefly poor mixing, instability during storage, shipping or packaging, as well as dosing limitations.

Disclosed are a controlled-release composition for oral administration comprising a complex of a hydrophilic alpha adrenergic blocker compound or its salt; and a clay mineral, and a method for preparing the same. The composition of the present disclosure has an in vivo release rate controlled further than that of conventional alpha adrenergic blocker compounds, thereby preventing side effects caused by a rapid increase in plasma drug concentration.

Disclosed are a controlled-release composition for oral administration comprising a complex of a hydrophilic alpha adrenergic blocker compound or its salt; and a clay mineral, and a method for preparing the same. The composition of the present disclosure has an in vivo release rate controlled further than that of conventional alpha adrenergic blocker compounds, thereby preventing side effects caused by a rapid increase in plasma drug concentration.

A composition containing carvone or a salt thereof as an active ingredient is disclosed. A new use of the composition is also disclosed. The composition is effective in whitening skin of a subject, and capable of exhibiting an excellent melanogenesis inhibitory effect. The composition has an excellent effect of inhibiting melanogenesis induced by melanocyte-stimulating hormone (αMSH), is safe for the human body, and has no or minimum adverse effects. Thus, the composition may be variously used as a material for cosmetics, functional health foods, food ingredients or additives, dietary supplement, nutraceutical composition, pharmaceuticals, quasi-drugs, or the like.

An anti-oxidative, energy-boosting, and anti-aging nutraceutical composition containing fullerene substituted with functional groups, a medium chain triglyceride (preferably black seed oil), and the composition optionally includes one or more energy molecules not bound to the fullerene. Preferred functional groups and energy molecules include beta-hydroxybutyrate (more preferably D-beta-hydroxybutyrate) and carboxylic acids (e.g., caprylic acid and/or capric acid).