A method for the fail-safe termination of in vivo drug delivery from an implantable drug delivery system, the method comprising: providing an implantable drug delivery system comprising: a housing having a reservoir for containing a drug, and a port for dispensing the drug to a patient; and an emergency deactivation unit disposed between the reservoir and the port, the emergency deactivation unit comprising a composite structure comprising a biocompatible ferromagnetic mesh open to fluid flow and a hydrophobic meltable material, the hydrophobic meltable material comprising at least one hole therein for enabling a fluid to pass through the hydrophobic meltable material; implanting the implantable drug delivery system within a patient; enabling the drug to flow from the reservoir, through the at least one hole in the hydrophobic meltable material and out the port; and when drug flow is to be terminated, applying a magnetic field to the composite structure, such that a current is induced in the ferromagnetic mesh which heats the ferromagnetic mesh and melts the hydrophobic meltable material, thereby closing the at least one hole in the hydrophobic meltable material and blocking drug delivery to the patient.

Provided is an electronic brake system. The electronic brake system includes: a reservoir in which a pressurized medium is stored; an integrated master cylinder including a master chamber and a simulation chamber; a reservoir flow path to communicate the integrated master cylinder and the reservoir; a hydraulic pressure supply device configured to generate a hydraulic pressure by operating a hydraulic piston according to an electrical signal output in response to a displacement of a brake pedal, and including a first pressure chamber provided on one side of the hydraulic piston accommodated to be movable in a cylinder block and connected to one or more wheel cylinders, and a second pressure chamber provided on another side of the hydraulic piston and connected to the one or more wheel cylinders; a hydraulic control unit having a first hydraulic circuit configured to control a hydraulic pressure transferred to two wheel cylinders and a second hydraulic circuit configured to control a hydraulic pressure transferred to other two wheel cylinders; and an electronic control unit configured to control valves based on hydraulic pressure information and displacement information of the brake pedal.

The present disclosure relates to an electronic brake system. The electronic brake system includes a reservoir in which a pressurized medium is stored, an integrated master cylinder including a master chamber and a simulation chamber, a reservoir flow path communicating the integrated master cylinder with the reservoir, a hydraulic pressure supply device provided to generate a hydraulic pressure by operating the hydraulic piston according to an electrical signal output in response to a displacement of the brake pedal, a hydraulic control unit including a first hydraulic circuit provided to control the hydraulic pressure transferred to two wheel cylinders and a second hydraulic circuit provided to control the hydraulic pressure transferred to the other two wheel cylinders, and an electronic control unit provided to control valves based on hydraulic pressure information and displacement information of the brake pedal.

The present application discloses a liquid seal method for on-off of gas pipeline and a device thereof, wherein a liquid-sealed U-shaped container being provided in the gas pipeline that requires to perform on-off control; a lifting mechanism using a leading screw controls the slider having a certain volume to immerse in or leave the liquid so as to raise or lower the liquid level. The U-shaped container has a structure with a wide top and a narrow bottom, the space of the U-shaped container is divided into two spaces with different sizes by a separating plate, and a liftable liquid-occupying device is located at the space having a larger volume; the upper and lower parts of the slider are tapered; and the driving device can be motor or hand wheel.

The present application discloses a liquid seal method for on-off of gas pipeline and a device thereof, wherein a liquid-sealed U-shaped container being provided in the gas pipeline that requires to perform on-off control; a lifting mechanism using a leading screw controls the slider having a certain volume to immerse in or leave the liquid so as to raise or lower the liquid level. The U-shaped container has a structure with a wide top and a narrow bottom, the space of the U-shaped container is divided into two spaces with different sizes by a separating plate, and a liftable liquid-occupying device is located at the space having a larger volume; the upper and lower parts of the slider are tapered; and the driving device can be motor or hand wheel.

A method for the fail-safe termination of in vivo drug delivery from an implantable drug delivery system, the method comprising: providing an implantable drug delivery system comprising: a housing having a reservoir for containing a drug, and a port for dispensing the drug to a patient; and an emergency deactivation unit disposed between the reservoir and the port, the emergency deactivation unit comprising a composite structure comprising a biocompatible ferromagnetic mesh open to fluid flow and a hydrophobic meltable material, the hydrophobic meltable material comprising at least one hole therein for enabling a fluid to pass through the hydrophobic meltable material; implanting the implantable drug delivery system within a patient; enabling the drug to flow from the reservoir, through the at least one hole in the hydrophobic meltable material and out the port; and when drug flow is to be terminated, applying a magnetic field to the composite structure, such that a current is induced in the ferromagnetic mesh which heats the ferromagnetic mesh and melts the hydrophobic meltable material, thereby closing the at least one hole in the hydrophobic meltable material and blocking drug delivery to the patient.

A method for the fail-safe termination of in vivo drug delivery from an implantable drug delivery system, the method comprising: providing an implantable drug delivery system comprising: a housing having a reservoir for containing a drug, and a port for dispensing the drug to a patient; and an emergency deactivation unit disposed between the reservoir and the port, the emergency deactivation unit comprising a composite structure comprising a biocompatible ferromagnetic mesh open to fluid flow and a hydrophobic meltable material, the hydrophobic meltable material comprising at least one hole therein for enabling a fluid to pass through the hydrophobic meltable material; implanting the implantable drug delivery system within a patient; enabling the drug to flow from the reservoir, through the at least one hole in the hydrophobic meltable material and out the port; and when drug flow is to be terminated, applying a magnetic field to the composite structure, such that a current is induced in the ferromagnetic mesh which heats the ferromagnetic mesh and melts the hydrophobic meltable material, thereby closing the at least one hole in the hydrophobic meltable material and blocking drug delivery to the patient.

Aspects of this disclosure relate to adjusting fluid flow using magnetically sensitive particles. Fluid can flow through an opening in a container. Magnetically sensitive particles can be confined within the container. A magnetic field can be applied to move the magnetically sensitive particles in the container to adjust flow of the fluid through the opening.

Aspects of this disclosure relate to adjusting fluid flow using magnetically sensitive particles. Fluid can flow through an opening in a container. Magnetically sensitive particles can be confined within the container. A magnetic field can be applied to move the magnetically sensitive particles in the container to adjust flow of the fluid through the opening.

The present application discloses a liquid seal method for on-off of gas pipeline and a device thereof, wherein a liquid-sealed U-shaped container being provided in the gas pipeline that requires to perform on-off control; a lifting mechanism using a leading screw controls the slider having a certain volume to immerse in or leave the liquid so as to raise or lower the liquid level. The U-shaped container has a structure with a wide top and a narrow bottom, the space of the U-shaped container is divided into two spaces with different sizes by a separating plate, and a liftable liquid-occupying device is located at the space having a larger volume; the upper and lower parts of the slider are tapered; and the driving device can be motor or hand wheel.