An air conditioning control system includes a casing including paths through which air passes, dampers arranged at an entrance and an exit of each of the paths and operated to open or close the entrance and the exit according to a control signal, a heat and mass exchanger including a hygroscopic material for absorbing moisture and arranged across the paths to be rotated with respect to the casing, a driving unit rotating the heat and mass exchanger, a heat exchange unit having a heat transfer medium flowing inside the heat exchange unit and arranged on at least one of the paths, and a controller opening or closing the entrance and the exit of the paths by applying a control signal to the dampers, and changing a rotation speed of the heat and mass exchanger by applying a control signal to the driving unit, according to operation modes.