A facility (1) for producing a container loaded with a biopharmaceutical fluid, includes: a container (2) wherein a biopharmaceutical fluid is placed (B); a control module (9) for controlling the filling of gas into the container (2); and an analysis module (10) for estimating a parameter for controlling the gas filling; and a pumping device (40) for generating a depression in the inner filling space (Vg).

The invention relates to a cryogenic container for storing and/or transporting a medium, in particular a biochemical and/or medical product. The cryogenic container comprises at least one primary container, which has at least one flexible film bag. The flexible film bag is designed to receive the medium. The cryogenic container furthermore comprises at least one secondary container, which at least partially surrounds the primary container and is preferably at least partially flexible. The secondary container has at least one opening for insertion of the primary container. The secondary container furthermore has at least one preferably at least partially flexible outer sleeve. The secondary container furthermore has at least one heat exchanger space, which is arranged between the outer sleeve and the flexible film bag and receives at least one fluid heat exchange medium.

A cooler is provided which has various improvements. The cooler may be a passive cooler or may be actively cooled for providing desirable cooling effects. The cooler may include an accessory system, for example, with bottle or can holders or a post holder which utilizes the weight of the cooler to support a sunshade. The accessory system may be positioned in various locations of the cooler, one location being in a recess which is utilized to open the cooler lid. The smart cooler may also comprise a cushion assembly which may be placed on an upper surface of the lid and may have straps to retain the cushion on the lid. The lid may be formed to accept and retain a cushion retaining feature so that the cushion does not excessively move from the top surface of the lid.

An automated cryogenic storage system includes a freezer and an automation system to provide automated transfer of samples to and from the freezer. The freezer includes a bearing and a drive shaft though the freezer, the drive shaft being coupled to a rack carrier inside the freezer and adapted to be coupled to a motor. The automation module includes a rack puller that is automatically positioned above an access port of the freezer. The rack puller engages with a sample rack within the freezer, and elevates the rack into an insulating sleeve external to the freezer. From the insulating sleeve, samples can be added to and removed from the sample rack before it is returned to the freezer.

A cryogenic system to remove energy includes a heat engine to store content at a predetermined temperature; one or more fans to deliver air flow through the heat engine; a cryogenic storage unit to store cryogen and having one or more insulated pipes thermally coupled to the heat engine to cool the heat engine; one or more reuse pipes coupled to one or more insulated pipes to send a portion of cryogen gas flow back to the cryogenic storage for reuse; a controller to maintain the predetermined temperature; and an on-board power generator to supply operating power to the controller and the one or more fans.

The invention relates to a cryogenic container for storing and/or transporting a medium, in particular a biochemical and/or medical product. The cryogenic container comprises at least one primary container, which has at least one flexible film bag. The flexible film bag is designed to receive the medium. The cryogenic container furthermore comprises at least one secondary container, which at least partially surrounds the primary container and is preferably at least partially flexible. The secondary container has at least one opening for insertion of the primary container. The secondary container furthermore has at least one preferably at least partially flexible outer sleeve. The secondary container furthermore has at least one heat exchanger space, which is arranged between the outer sleeve and the flexible film bag and receives at least one fluid heat exchange medium.

A cryogenic specimen shipping container using nitrogen gas for transport of a cryogenic specimen to a cryogenic storage chamber or Dewar vessel for storage. The cryogenic specimen shipping container may comprise an outer container, an inner container received within the outer container, and a gas pathway located between the outer container and the inner container and configured to expel the nitrogen gas.

The present invention stores a cooled sample subjected to freezing treatment, or the like, while preventing the formation of condensation and frost-like substances and loads the sample into a sample holder for observation using a charged particle beam device. The present invention is provided with a main body for storing a sample and a lid unit mounted above the main body and is characterized in that the main body is divided into a first space and a second space by a partition member; the first space accommodates a cooling medium for cooling the sample; the second space has, disposed therein, a heating unit for heating the cooling medium accommodated in the first space; and the lid unit has, formed therein, a discharge port for discharging the gas generated by the heating of the cooling medium to the outside.

A reservoir for storing products at cryogenic temperatures is provided. The reservoir includes an insulated vacuum tank delimiting a storage volume having an open upper end. The reservoir includes a mobile lid for closing and opening the storage volume. The reservoir also includes a controlled actuating member mechanically connected to the lid in order to move the lid. The actuating member being able to move between a first position that places the lid in its position for closing the storage volume of the tank and a second position that places the lid in a position for opening the storage volume of the tank.

A shipping container is described for use with methods for monitoring and controlling shipment of a temperature controlled material and determining the remaining useful life of a Thermal Source contained within the shipping container. The container comprises an inner enclosure adapted to carry one or more commodities during shipment, a bladder conformed to the inner surface of the inner chamber, or a plate upon which commodities are place, and instrumented with at least one transducer and at least one processing device configured to receive measurements from the at least one transducer. The processing device communicates the measurements to a networked device upon detecting the presence of a network. The networked device may transmit commands to the processing device that causes the processing device to adjust a configuration parameter.