Disclosed is a method of maintaining an initial quantity of mRNA vaccine cargo in an EPS container containing dry ice as a passive coolant during shipment from a manufacturing site, wherein the initial quantity of mRNA vaccine cargo is shipped to a first depot and then repackaged into smaller quantities at one or more additional depots en route to the final destinations. Dry ice can be added or ordered in advance to be available at the next depot for the cargo. Indicators show the status of the cargo and whether it has undergone unacceptable temperature or humidity excursions.

Methods, systems, devices and/or apparatuses for a hardened reusable shipping container. The hardened reusable shipping container includes a lid. The lid is configured to be opened and closed. The hardened reusable shipping container includes a base enclosure. The base enclosure is coupled to the lid and has a payload area. The payload area is configured to receive a payload and maintain a temperature of an environment surrounding the payload. The hardened reusable shipping container includes an insert. The insert is configured to be positioned within the payload area to cool or maintain the temperature of the environment surrounding the payload.

A cooling element includes a container, the container defining an internal volume within one or more walls of the container. The volume is air-tight sealed, and the container is configured for containing dry ice (solid carbon dioxide), releasing carbon dioxide gas from the volume and blocking ingress of ambient gas into the volume. Additionally, a shipping box includes a thermally insulated volume therein, and is configured for holding a receptacle and one or more cooling elements, wherein the one or more cooling elements are arranged to enclose the receptacle. Further, a method is disclosed for thermal stabilisation of such a receptacle by using the cooling element or shipping box. The receptacle is arranged for holding a product such as a (bio)pharmaceutical substance and/or advanced therapy medicinal product(s).

A cooling element includes a container, the container defining an internal volume within one or more walls of the container. The volume is air-tight sealed, and the container is configured for containing dry ice (solid carbon dioxide), releasing carbon dioxide gas from the volume and blocking ingress of ambient gas into the volume. Additionally, a shipping box includes a thermally insulated volume therein, and is configured for holding a receptacle and one or more cooling elements, wherein the one or more cooling elements are arranged to enclose the receptacle. Further, a method is disclosed for thermal stabilisation of such a receptacle by using the cooling element or shipping box. The receptacle is arranged for holding a product such as a (bio)pharmaceutical substance and/or advanced therapy medicinal product(s).

A modular box assembly includes a box; a first thermal liner constructed of a first length of pre-laminated material, the pre-laminated material comprising an insulation batt in facing contact with a first sheet and with a second sheet, the first thermal liner defining three first liner panels; and a second thermal liner constructed of a second length of the pre-laminated material, the second thermal liner defining three second liner panels. A bottom box panel is covered by one of a first liner panel not covering any side box panel and a second liner panel not covering any side box panel. The insulation batt is formed from a mixture of reinforcement fibers and thermoplastic binder fibers, the reinforcement fibers comprising one of natural fibers, recycled cardboard, and a mixture of recycled cardboard and paper fibers.

A modular box assembly includes a box with side panels defining a box cavity, a first thermal liner positioned within the box cavity, the first thermal liner including a first insulation batt disposed between sheets, the first thermal liner defining three first liner panels, at least one box side panel being covered by a first liner panel, and a second thermal liner positioned within the box cavity, the second thermal liner including a second insulation batt disposed between sheets, the second thermal liner defining three second liner panels. At least one other of the side box panels is covered by a second liner panel. The bottom box panel is covered by either a first liner panel not covering any side box panel or a second liner panel not covering any side box panel. Each insulation batt can be formed from a mixture of thermoplastic binder fibers and reinforcement fibers.

A method and an arrangement for preventing a formation of a hurricane storm and/or dispersing a tropical cyclone storm defining an eye are disclosed. The arrangement is dropped from an aircraft into water in the eye of the storm and includes at least first and second vessels filled with a refrigerant. The first and second vessels are pressure resistant, spherical and sinkable with the first vessel having a first sinking velocity and the second vessel having a second sinking velocity. The first sinking velocity is greater than the second. The first and second vessels have respective first and second opening mechanisms for releasing the refrigerant at pregiven respective depths. The first opening mechanism is configured to open at a first depth and the second opening mechanism is configured to open at a second depth. The first depth is greater than the second depth.

The invention relates to a transport container, in particular for the passive chilled transportation of pharmaceuticals and/or foodstuffs, having an external container (3) which has an external container base (31) and an external container wall (32); having an internal container (2) which is able to be inserted into the external container (3) and retrieved from the external container (3) and which has an internal container base (21) and an internal container wall (22); wherein the internal container (2) for cargo (10) forms an internal container space (23) which is open toward the top; wherein a spacing (7) on the external container wall (32) and on the external container base (31) is present between the internal container (2) and the external container (3); wherein at least one thermal insulation element (4), in particular a vacuum insulation panel, is disposed between the internal container (2) and the external container (3), in particular the external container wall (32); wherein at least one retrievable PCM element (5) is disposed and/or able to be disposed between the internal container (2) and the external container (3), in particular the thermal insulation element (4).

A box assembly includes a box defining a box cavity within the box; and at least one insulated panel disposed within the box cavity, the at least one insulated panel including at least one board and at least one insulation batt, the at least one board laminated to the at least one insulation batt, the at least one insulated panel configured to at least partially insulate the box cavity.

The invention relates to a transport box (1), in particular for partially prepared meals and food, comprising a lower part (11) having a receiving space (2) limited by lateral walls (12) and at least one base (22). The receiving space (2) can be sealed by a cover (3). The cover (3) has a coolant space (33) for receiving a coolant (200). In addition, the lower part (11) has two receiving spaces (2). The receiving spaces (2) can be sealed by a respective cover (3). The covers (3) can be arranged in two cover positions (13, 23) sealing the receiving space (2). The cover positions (13, 23) differ in terms of a cooling effect that can be achieved by means of the coolant (200), such that the transport box (11) offers at least two different options for temperature control via the selection of the cover positions (13, 23).