Disclosed is a jacketed, tiered baffle, bioreactor tank comprising an outer cylindrical-shaped jacket and a cylindrical tank having an inner tank surface defining a chamber configured for supporting a flexible bag disposed within the chamber, and an outer tank surface having tiered baffles configured for routing a heat exchange fluid around the entirety of the outer tank surface, the cylindrical tank disposed axially within the outer cylindrical-shaped jacket. The outer cylindrical-shaped jacket is sealed to the cylindrical tank in a manner sufficient to prevent or minimize loss of the heat exchange fluid.

A heat exchange module for use in a chemical, pharmaceutical or biological reactor system includes a generally hollow body having an interior space for receiving a replaceable or single use reactant container, and at least one thermally conductive surface adapted to contact the replaceable reactant container to facilitate heat transfer, a fluid circulation path formed within the body between an outer wall of the body and an inner wall of the body through which a heat exchange fluid can be circulated, and at least one baffle protruding from the inner wall of the body into the interior space.

A system (20) including a heater/cooler module (22) to heat/cool a first fluid in a primary circuit (28), a heat transfer fluid circuit (24) to provide a second fluid to a target device (38) to heat/cool the target device (38), and a heat exchanger (26) including at least part of the primary circuit (28) and at least part of a secondary circuit (36) through which the second fluid flows to facilitate heat transfer between the first fluid and the second fluid. The primary circuit (28) and the secondary circuit (36) are separate circuits and the first fluid and the second fluid remain separated in the system. Also, the system is modular, such that the elements can be stacked to increase heating/cooling capability and/or to increase the number of heating/cooling channels, and the system is compatible with portable applications, such as ambulance, aircraft, and helicopter applications, and with battery operation and/or the use of uninterruptible power supplies.

A radiant cooling device comprises at least one fluidic layer including one or more micro-channel liquid-circuits and at least one structural layer coupled to the at least one fluidic layer. The device further includes a plurality of folds such that the device has a three-dimensional surface geometry having a plurality of inclined surfaces.

Computer modelling methods and foundry methods for copper-nickel coolant pipes cast-in-copper coolers are combined. First, Computational Fluid Dynamics and/or Finite Element Analysis steps verify geometric computer aided design models and materials choices, point-by-point heat distribution, and heat flows. And second, casting steps to commit an acceptable last thickness iteration of a thermal buffer part in simulation to casting it in a foundry. In the foundry, casting conditions are empirically developed to yield all but slight, unclustered bonding imperfections at a concentric diffusion interface of the pipes and surrounding solidified casting that improve the thermal conductivity of furnace-block coolers that incorporate coolant pipes. The combined methods verify in simulation that operational thermal stresses at the pipe-casting interface stay in-bounds of material stress limits, and that the peak temperatures on the hot face do not rise above 450 C.

The present invention provides systems, methods, and articles for temperature conditioning a surface. An article is formed from a first layer having a plurality of openings and a second layer having a corresponding plurality of openings. At least one interior chamber constructed and configured to retain a fluid without leaking is defined between an interior surface of the first layer and an interior surface of the second layer. At least one flexible fluid supply line delivers the fluid to the at least one interior chamber. At least one flexible fluid return line removes the fluid from the at least one interior chamber. At least one control unit that is operable to selectively cool or heat the fluid is attached to the at least one flexible fluid supply line and the at least one flexible fluid return line.

A heat exchanger pipe system is provided for transporting viscous fluids, including a plurality of individual heat exchangers designed as pipe elements and having a predefined control temperature and/or pressure distribution along the pipe system and in the cross-section of the pipes. The heat exchangers, which are in the form of pipe elements, are arranged at regular distances in the pipe system. The regular distances are selected in such a manner that a predetermined temperature and/or pressure distribution is maintained along the pipe system, tempering apparatus of a viscous fluid transported in the heat exchanger pipe are arranged in the heat exchangers and optional mixing elements which are used to maintain, in accordance with the pipe cross-section, a predetermined temperature and pressure distribution in the cross section of the pipes, and at least 30% of the length of the heat exchanger pipe system is equipped with heat exchangers.

A system (20) including a heater/cooler module (22) to heat/cool a first fluid in a primary circuit (28), a heat transfer fluid circuit (24) to provide a second fluid to a target device (38) to heat/cool the target device (38), and a heat exchanger (26) including at least part of the primary circuit (28) and at least part of a secondary circuit (36) through which the second fluid flows to facilitate heat transfer between the first fluid and the second fluid. The primary circuit (28) and the secondary circuit (36) are separate circuits and the first fluid and the second fluid remain separated in the system. Also, the system is modular, such that the elements can be stacked to increase heating/cooling capability and/or to increase the number of heating/cooling channels, and the system is compatible with portable applications, such as ambulance, aircraft, and helicopter applications, and with battery opera-tion and/or the use of uninterruptible power supplies.

A temperature control apparatus is provided, which is capable of, even when it is necessary to perform control by means of valves in a plurality of channels, promptly controlling a temperature of an area to be temperature-controlled promptly to a desired temperature. Passage and blockage of a heating medium passing through a first supply channel to a mixing channel, a temperature of the heating medium being controlled by a first temperature regulating unit at a predetermined temperature, and passage and blockage of a heating medium passing through a second supply channel to the mixing channel, a temperature of the heating medium being controlled by a second temperature regulating unit, are controlled by a valve unit. The valve unit includes a first spool valve and a second spool valve, which are coupled through a heat insulating layer.

Methods and systems for controlling temperatures in plasma processing chamber via pulsed application of heating power and pulsed application of cooling power. In an embodiment, fluid levels in each of a hot and cold reservoir coupled to the temperature controlled component are maintained in part by a coupling each of the reservoirs to a common secondary reservoir. Heat transfer fluid is pumped from the secondary reservoir to either the hot or cold reservoir in response to a low level sensed in the reservoir. In an embodiment, both the hot and cold reservoirs are contained in a same platform as the secondary reservoir with the hot and cold reservoirs disposed above the secondary reservoir to permit the secondary reservoir to catch gravity driven overflow from either the hot or cold reservoir.