The present invention pertains to inter alia therapeutic delivery vesicles, for instance exosomes or microvesicles, comprising polypeptide constructs, methods for producing said therapeutic delivery vesicles, pharmaceutical compositions and medical uses thereof. The therapeutic polypeptide constructs comprised in the extracellular delivery vesicles enable sequestering target molecules of interest, to treat e.g. neuro-inflammatory diseases and cancer.

The invention relates to a hydraulic rotator (11) for rotating a tool with respect to a crane arm, the hydraulic rotator comprising a first attachment piece (12) for connection to a crane arm and a second attachment piece (13) for connection to a tool; and a stator (14) and a rotor (15), the rotor (15) being rotatably arranged inside the stator (14) to rotate around an axial axis (A), wherein the rotor (15) comprises vanes (18) that are biased to extend radially outwards from said rotor (15), and wherein the stator (14) comprises an inner circumferential surface (25) to receive said vanes (18), which inner circumferential surface (25) comprises at least two chambers (19a) arranged to receive each vane of said vanes (18) to a first extent, and at least two shallow portions (19b) arranged to receive each vane of said vanes (18) to a second extent, which is substantially less compared to said first extent, wherein said inner circumferential surface (25) is arranged to receive at least a tip portion of the vanes (18) throughout its whole periphery.

The invention relates to a hydraulic rotator (11) for rotating a tool with respect to a crane arm, the hydraulic rotator comprising a first attachment piece (12) for connection to a crane arm and a second attachment piece (13) for connection to a tool; and a stator (14) and a rotor (15), the rotor (15) being rotatably arranged inside the stator (14) to rotate around an axial axis (A), wherein the rotor (15) comprises vanes (18) that are biased to extend radially outwards from said rotor (15), and wherein the stator (14) comprises an inner circumferential surface (25) to receive said vanes (18), which inner circumferential surface (25) comprises at least two chambers (19a) arranged to receive each vane of said vanes (18) to a first extent, and at least two shallow portions (19b) arranged to receive each vane of said vanes (18) to a second extent, which is substantially less compared to said first extent, wherein said inner circumferential surface (25) is arranged to receive at least a tip portion of the vanes (18) throughout its whole periphery.

The present invention provides a vane-type compressed air motor, comprising a casing, a rotor and vanes, wherein the casing is provided with an air inlet and an air outlet, a plurality of vanes are inserted into the rotor, and the rotor is disposed inside the casing to form a rotating body. The difference from the prior art is that the present invention further comprises a vane stopper, an inner retainer ring, stop bearings and a kit. Using the technique provided by the present invention, the wear of the vanes can be significantly reduced even under high pressure conditions, such that the service life of the vane is prolonged, air leakage is prevented, and the motor power can be improved. The present invention can also be used in various tools, having a significant effect of saving a lot consumption and cost, thereby having broad market prospects.

The present invention provides a vane-type compressed air motor, comprising a casing, a rotor and vanes, wherein the casing is provided with an air inlet and an air outlet, a plurality of vanes are inserted into the rotor, and the rotor is disposed inside the casing to form a rotating body. The difference from the prior art is that the present invention further comprises a vane stopper, an inner retainer ring, stop bearings and a kit. Using the technique provided by the present invention, the wear of the vanes can be significantly reduced even under high pressure conditions, such that the service life of the vane is prolonged, air leakage is prevented, and the motor power can be improved. The present invention can also be used in various tools, having a significant effect of saving a lot consumption and cost, thereby having broad market prospects.

Various designs for hydraulic devices are disclosed including hydraulic devices that can include a rotor and a ring are disclosed. The rotor can be disposed for rotation about an axis and can have a plurality of plurality of vanes extending therefrom. The ring can be disposed at least partially around the rotor and the ring, and the rotor can be in communication with a port for ingress or egress of the hydraulic fluid to or from adjacent the rotor. The ring defines a cavity adjacent to and in communication with the port, the cavity allows the hydraulic fluid to be disposed adjacent at least one of the plurality of vanes when the at least one of the plurality of vanes is transiting the port.

Various designs for hydraulic devices are disclosed including hydraulic devices that can include a rotor and a ring are disclosed. The rotor can be disposed for rotation about an axis and can have a plurality of plurality of vanes extending therefrom. The ring can be disposed at least partially around the rotor and the ring, and the rotor can be in communication with a port for ingress or egress of the hydraulic fluid to or from adjacent the rotor. The ring defines a cavity adjacent to and in communication with the port, the cavity allows the hydraulic fluid to be disposed adjacent at least one of the plurality of vanes when the at least one of the plurality of vanes is transiting the port.

The disclosure discloses a slide vane, a pump body assembly, a compressor and an air conditioner having the same. The pump body assembly includes a cylinder assembly, a flange portion, a rotating shaft and the slide vane. The flange portion is connected to the cylinder assembly, a working cavity is formed between the flange portion and the cylinder assembly, and an avoidance portion is provided on a surface, located in the working cavity, of the flange portion. A limiting structure is provided in an accommodation portion. The limiting structure is provided with an avoidance position in the accommodation portion, and at least part of the limiting structure is provided with a limiting position protruded out of a surface of the accommodation portion. Such a configuration avoids friction occurring between the head of the slide vane and the cavity wall of the working cavity.

A rotary internal combustion motor has a stator that houses a compartment defined by two opposite planar surfaces and by an annular surface with elliptical profile, inside which a rotor rotates, which includes a cylindrical drum surrounded by an annular chamber, which is divided into multiple portions by a regularly spaced set of radial blades that are slidingly housed in the cylindrical drum. The motor also has at least one pair of inlet openings, at least one pair of outlet openings, at least one pair of injectors, at least one pair of spark plugs, and at least one pair of pre-heating spark plugs.

A rotary internal combustion motor has a stator that houses a compartment defined by two opposite planar surfaces and by an annular surface with elliptical profile, inside which a rotor rotates, which includes a cylindrical drum surrounded by an annular chamber, which is divided into multiple portions by a regularly spaced set of radial blades that are slidingly housed in the cylindrical drum. The motor also has at least one pair of inlet openings, at least one pair of outlet openings, at least one pair of injectors, at least one pair of spark plugs, and at least one pair of pre-heating spark plugs.