The invention relates to a feed or a feed supplement in the form of modularly stacked objects for the controlled release of nutrients and/or physiologically active substances for monogastric animals, comprising a core and a coating of the core, wherein the core has an aqueous phase with water-soluble active substances and a lipid phase with fat-soluble active components, in which the lipid phase comprises a mineral filler, and the coating layers and the aqueous phases advantageously have a dispersed exfoliated mineral filler.

The present disclosure provides an improvement of existing L-arginine containing supplements by providing both hydrogen crystals (H.sub.2) and co-enzyme Q10 (Co-Q10) to produce a nutrient formulation, including compositions containing said formulation and methods of administering such formulation.

The present disclosure provides an improvement of existing L-arginine containing supplements by providing both hydrogen crystals (H.sub.2) and co-enzyme Q10 (Co-Q10) to produce a nutrient formulation, including compositions containing said formulation and methods of administering such formulation.

The invention relates to a process for producing a plurality of capsules, each comprising an external shell of crosslinked hydrogel surrounding a central core, according to which a hydrogel solution and a composition of interest, intended to form the central core, are concentrically co-extruded so as to form mixed drops, each comprising a layer of hydrogel solution surrounding a drop of liquid composition of interest, characterized in that the co-extrusion step is carried out above a crosslinking aerosol so that the mixed drops pass through said crosslinking aerosol, such that the layer of hydrogel solution at least partially crosslinks around the drop of liquid composition of interest on contact with said aerosol.

Multiparticulate compositions including an active agent and a gelling agent are disclosed. The multiparticulate compositions are prepared by an aqueous-based spray and congeal process.

The invention relates to a process for the preparation of dry lyophilized powdered formulations of probiotic bacteria for monogastric animal (for example poultry birds) using a combination of different polymers through the process of encapsulation. The resulting lyophilized powders of probiotic bacteria are having increased viability during animal feed processing, storage and upon transfer to the monogastric animal's digestive system.

A process for producing a nanoemulsion formulation comprising the following main stages: (a) extraction of natural antioxidants from peels or seeds of fruits, vegetables or cereals, wherein the extraction is carried out with pure water, with a concentration of the extracted natural antioxidants with a vacuum distillation method between 0.5-15 inHg at 20-60° C. for 10-95 minutes until the concentration of the extracted natural antioxidants is between 10-50 wt % and then a tangential nanofiltration of the concentrated natural antioxidants; (b) encapsulation of the natural antioxidants; (c) formation of a nanoemulsion; and (d) cryodrying of the formed nanoemulsion.

A process for producing a nanoemulsion formulation comprising the following main stages: (a) extraction of natural antioxidants from peels or seeds of fruits, vegetables or cereals, wherein the extraction is carried out with pure water, with a concentration of the extracted natural antioxidants with a vacuum distillation method between 0.5-15 inHg at 20-60° C. for 10-95 minutes until the concentration of the extracted natural antioxidants is between 10-50 wt % and then a tangential nanofiltration of the concentrated natural antioxidants; (b) encapsulation of the natural antioxidants; (c) formation of a nanoemulsion; and (d) cryodrying of the formed nanoemulsion.

An industrially scalable microcapsule, fiber or film forming process and formulations suitable for use in conventional spray drying systems are provided. The one-step spray drying process utilizes formulations of a first ionic polymer, a second ionic polymer with an isoelectric point (pI.sub.2) or acid dissociation constant (pKa.sub.2) that is greater than the isoelectric point (pI.sub.1) or acid dissociation constant (pKa.sub.1) of the first ionic polymer and a volatile base or volatile acid. Volatilization of the volatile base or acid of the spray formulation changes the pH of the solution and changes the charge of the second ionic polymer initiating electrostatic interactions with the first ionic polymer through complex coacervation. Microcapsules formed by the complex coacervation process can stabilize bioactive components as well as control the release of the bioactive components for a variety of applications.

A dietary supplement and method for synthesis of the same are disclosed. In one embodiment of the method, an NADH component is provided that includes at least partially microencapsulated nicotinamide having nicotinamide blended with water. A supplement component, such as collagen, coenzyme Q10, vitamins, and minerals, is provided. A mixed component, which is a liquid, is formed by mixing the NADH component with the supplement component at ambient conditions. The mixed component is subjected to a fill production process.