Membrane pump device, wherein the membrane pump device comprises a housing, and the housing contains a first and a second chamber, wherein the first chamber is separated from the second chamber by a movable membrane, while a liquid being pumped can be introduced in the first chamber, and a drive liquid can be introduced into the second chamber, wherein the second chamber has an outlet opening, and the outlet opening is present on an outer side of the housing. The membrane pump device is characterized in that the membrane pump device comprises a valve, while the valve is arranged at the outlet opening and closes off the second chamber from the outside.

A fluid handling cassette, such as that useable with an automated peritoneal dialysis (APD) cycler device or other infusion apparatus, may include a generally planar body having at least one pump chamber formed as a depression in a first side of the body and a plurality of flowpaths for a fluid that includes a channel. A patient line port may be arranged for connection to a patient line and be in fluid communication with the at least one pump chamber via at least a first one of said flowpaths, and an optional membrane may be attached to the first side of the body over the at least one pump chamber. In one embodiment, the membrane may have a pump chamber portion with an unstressed shape that generally conforms to the depression of the at least one pump chamber in the body and is arranged to be movable for movement of the fluid in a useable space of the at least one pump chamber. One or more spacers may be provided in the at least one pump chamber to prevent the membrane from contacting an inner wall of the at least one pump chamber. The patient line, a drain line, and/or a heater bag line may be positioned to be separately occludable in relation to one or more solution lines that are connectable to the cassette.

Devices and methods for operating a diaphragm compressor system provide high output pressure and high throughput. In some embodiments, modular diaphragm compressors are stacked with a clamping mechanism pressing the compressor modules together. In embodiments, multiple stacks are provided as stages of a pressurization process. In embodiments, a main stage valve controls one or more pressure circuits for one or more hydraulic actuators of compressor modules. In embodiments, orifices configured for damping are incorporated to control actuator piston movement within a compressor module.

A modular pump features a gas-control-and-drive-unit (GCDU), a cartridge-style-pumping-module (CSPU) and a retainer clip (RC). The GCDU includes a GCDU-housing to receive/provide gas to a gas-passageway causing a GCDU-force in one direction; an actuator-rod-and-slide-valve-arrangement (AR/SVA) to respond to a CSPM-force and exhaust the gas from the GCDU-housing causing a GCDU-exhaustion-force in an opposite direction; and a GCDU-coupling-member. The CSPM includes a CSPM-housing to receive a fluid to be pumped, and a piston-and-dual-diaphragm-arrangement (PDDA) to respond to the GCDU-force, provide the CSPM-force and pump the fluid from the CSPM, and to respond to the GCDU-exhaustion-force and pump the fluid from the CSPM. The CSPM-housing includes a CSPM coupling member to detachably couple to the GCDU-coupling-member. The RC detachably couples a piston of the PDDA and an actuator rod of the AR/SVA, so the CSPM attaches/detaches from the GCDU using a three-step process for field replacement using the RC.

A switching unit may be provided for connecting a first pneumatic unit and a second pneumatic unit of a pneumatic system together. The switching unit comprises a main body having: a channel structure which extends through the main body; a first and a second inlet for introducing a pressure into the channel structure; a first and a second outlet for discharging at least some of the pressure from the channel structure; and a first and a second valve; wherein the first inlet can be brought into a pressure-exchange connection to the first outlet via a first channel by setting a first switch position of the first valve or to the second outlet via a second channel by setting a second switch position of the first valve, and wherein the second inlet can be brought into a pressure-exchange connection to the first outlet via a third channel by setting a first switch position of the second valve or to the second outlet via a fourth channel by setting a second switch position of the second valve.

A diaphragm pump mechanically operable air pressure regulator assembly that is operable in direct response to the relative operation of an associated diaphragm pump system. The regulator assembly includes a housing that is constructed to receive a static air pressure signal. A cam arrangement is disposed in the regulator housing and is constructed to mechanically cooperate with a shaft of a respective diaphragm pump system. Axial translation of the shaft of the diaphragm pump system effectuates rotation of the regulator cam arrangement. The relative motion of the cam arrangement with respect to the regulator housing manipulates a force associated with a biasing device disposed in the regulator and thereby the relative degree of the static air pressure signal that is communicated to the respective diaphragm pump system.

Multiple diaphragm pumps are known in the art that are operated by compressed air and in which the valves are controlled by a slide element. The slide element is magnetically actuated without mechanical engagement involved in the actuation. This has the consequence that only a small amount of force can be applied which may not be sufficient due to static friction of the valve seal. The invention presents a hybrid solution which facilitates a mechanical actuation of a valve piston provided for valve control as well as a magnetic overcoming of a dead center that may be reached by the valve piston and the diaphragm piston that actuates the diaphragms of the multiple diaphragm pump.

A precision pump system having a motor driver for accurately and repeatedly delivering process fluid, (e.g., photo chemicals) using a pumping fluid with minimal process fluid loss to a fabrication process and whereby the motor driver can be easily and quickly replaced without interrupting the fluid flow path. This is accomplished with the use of a process fluid reservoir and a pumping fluid reservoir that are associated with the pump, either integrated with the pump or closely adjacent. In addition, this precision pump system can be remotely monitored, viewed and controlled over the Internet. In addition, trapped process fluid within a downstream filtering block can be recirculated to the process fluid reservoir when trapped gas in the filter is removed. Furthermore, a nitrogen gas source is connected to the process fluid reservoir via a valve in case a need to insert a gas is required.

A medical infusion fluid handling system, such as an automated peritoneal dialysis system, may be arranged to de-cap and connect one or more lines (such as solution lines) with one or more spikes or other connection ports on a fluid handling cassette. This feature may reduce a likelihood of contamination since no human interaction is required to de-cap and connect the one or more lines and the one or more spikes. For example, the automated peritoneal dialysis system may include a carriage arranged to receive the one or more lines each having a connector end and a cap. The carriage may move along a first direction so as to move the connector ends of the one or more lines along the first direction, and a cap stripper may be arranged to engage with the caps on the the one or more lines on the carriage. The cap stripper may move in a second direction transverse to the first direction, as well as to move with the carriage along the first direction.

A pump cassette comprising an outer flexible membrane covering flowpaths, valve chambers and pump chambers of the cassette is designed to be actuated by a control gasket on a base unit arranged to move designated valve and pump portions of the cassette membrane. The performance of a cassette valve may improved by optimizing the configuration of the valve control region of the control gasket overlying the cassette valve. This may improve both fluid flow through the valve and reduce the amount of vibratory noise associated with opening the valve. The gasket valve control or actuation region is at least partially bounded by a vacuum channel facing the outside of the gasket so that a constant vacuum can be applied between the gasket valve control or actuation region and the adjacent portion of the cassette membrane. An improved version of the vacuum channel comprises a flexible inner wall (contiguous with the valve control region) so that the inner wall flexes or partially collapses away from the cassette valve seat, while still maintaining patency of the vacuum channel during the application of negative pressure on the gasket valve actuation region to open the cassette valve.