A peristaltic pump can include a chassis and a chassis retaining portion forming a cavity. The pump can also include a rotor, a cover, and a linkage. The rotor can be disposed within the cavity such that tubing can be held between the rotor and the chassis and/or the chassis retaining portion. The linkage can couple the cover to the chassis. The linkage can include an arm. When opening the cover, the arm can pivot such that the chassis moves away from the chassis retaining portion to widen the cavity. When closing the cover, the arm can pivot such that the chassis moves toward the chassis retaining portion. When closed, a stop can restrict further movement of a corresponding member toward the chassis retaining portion.

The present invention relates to devices and methods for improving and evaluating stability of pumped protein solutions in cross-flow filtration applications. Inter alia, the present invention provides a peristaltic pump for cross-flow filtration having a pump head, wherein the pump head comprises a stepped occlusion plate and at least one pump roller, wherein a tubing is to be arranged between the stepped occlusion plate and the at least one pump roller, wherein the stepped occlusion plate has a specific configuration.

A sensor system for a volumetric pump operating according to the linear peristalsis principle includes at least one sensor unit; at least one sensor transmitter unit; and a sensor output signal processing unit. The sensor transmitter unit is arranged to apply a detection variable varying as a function of a travel position to the sensor unit along a predetermined travel along which a fixedly arranged sensor unit and a movably arranged sensor transmitter unit or a movably arranged sensor unit and a fixedly arranged sensor transmitter unit are moving relative to each other. The sensor unit is configured to output a detection signal corresponding to a travel position on the basis of the varying detection variable. The sensor output signal processing unit is arranged to receive the detection signal output by the sensor unit and discriminate at least three travel positions on the basis of the received detection signal.

A tube pump having small driving energy is provided. The tube pump includes: a flexible tube for conveying a fluid; a holder part holding the tube so that the tube is at least partially bent; a driving part; and at least one pressing part, rotationally driven around a first central axis by the driving part, and pressing the tube along the bent portion of the tube held by the holder part while rotating around the first central axis, thereby conveying the fluid in the tube. The pressing part has an inclined plane inclined from the side of the tube toward the side of the pressing part in a radially outward direction with reference to the first central axis.

The present invention involves a rotary peristaltic pump and associated method employing the relaxation of pressure on flexible tubing between the rotor and stator of the pump to restore the rotor to a start angle while a valve on the output of the pump is closed to avoid progress of fluid through the system. Three different implementations of the pump and method are presented including reciprocating the stator, reciprocating the rotor, and retracting the idler rollers of the rotor into the rotor to relieve the pressure on the flexible tubing. A controller ensures the appropriate switching and timing of the valve and rotor of the pump. The pump and associated method are directed to the precision dispensing of pharmaceutical fluids into containers, including containers held in container nests.

A peristaltic pump includes a rotating member operably coupled to a drive. The rotating member includes a plurality of rollers arranged in a circular configuration. A guide member defines a channel configured to direct a peristaltic tube around the rotating member so that the peristaltic tube interfaces with the plurality of rollers. The peristaltic tube is pressed against the plurality of rollers by a retaining shoe. The retaining shoe contains surface irregularities configured to restrict movement of the peristaltic tube. A keeper braces the restraining shoe against the peristaltic tube. The rotating rollers compressing the peristaltic tube against the retaining shoe as the rotating member rotates results in a peristaltic action that produces a nearly pulse free linear flow.

A disposable cartridge (20) for a peristaltic micro pump is disclosed. The cartridge comprises a housing (21) with an inlet connector (25) and an outlet connector (26). A fluid channel (23) extends in the housing (21) between the inlet and the outlet with a channel section (22) of the fluid channel (23) provided by a flexible tube (24). One or more openings are provided adjacent to the channel section (22) in the housing (21) allowing one or more pump engaging elements of a pump drive to engage the flexible tube (24), compressing the flexible tube (24) to pump fluid through the fluid channel (23). Sealing elements (31, 32) with double flange extensions (31a, 31b) having a first inner flange (31a, 32a) and a second outer flange (31b, 32b) are provided to seal at the connectors (25, 26) and fix the tube (24) in the housing (21).

A peristaltic pump has an arcuate raceway with a partially concave inner surface extending through an arc of at least one hundred eighty degrees (180). The arc defines a midpoint, and a rotor faces the inner surface of the raceway and is both rotatable relative to the raceway and translationally movable relative to the raceway between a pump position, wherein the rotor is spaced from the midpoint a first distance, and a tube load position, wherein the rotor is spaced from the midpoint a second distance greater than the first distance. A motor is coupled to the rotor to rotate the rotor plural are rollers arranged on the rotor to contact tubing disposed between the rotor and the raceway when the rotor is in the pump position. The motor is prevented from stopping at a predetermined angular position to facilitate loading and unloading tubing.

The present invention relates to devices and methods for improving and evaluating stability of pumped protein solutions in cross-flow filtration applications. Inter alia, the present invention provides a peristaltic pump for cross-flow filtration having a pump head, wherein the pump head comprises a stepped occlusion plate and at least one pump roller, wherein a tubing is to be arranged between the stepped occlusion plate and the at least one pump roller, wherein the stepped occlusion plate has a specific configuration.

Pump heads for peristaltic pump assemblies are provided. For example, a pump head for a peristaltic pump comprises an occlusion bed, a rotor guide, a rotor assembly positioned between the occlusion bed and the rotor guide, and a pathway for tubing. The pathway comprises an inlet portion, an outlet portion, and a connecting portion that connects the inlet and outlet portions. The inlet portion is defined between the occlusion bed and the rotor guide, the outlet portion is defined between the occlusion bed and the rotor guide, and the connecting portion is defined between the occlusion bed and the rotor assembly. Further, the occlusion bed is movable with respect to the rotor guide and the rotor assembly. In exemplary embodiments, the pump head urges fluid flow through the tubing to supply a cooling fluid to a medical probe assembly for delivering energy to a patient's body.