A valve for use in connection with microfluidic devices includes a safety feature such that flow is controlled even in the case of a loss of power, thus having applications in critical applications such as the precise delivery of drugs over time. The valve may be used in connection with multiple tubes delivering drugs, and may be used with a pump, such as an electrochemical pump, to provide the force to move the fluids containing drugs for delivery. In certain applications, more than one medicine may be delivered and metered independently using a single pump with multiple reservoirs and valves.

An encapsulated valve system includes a first housing portion having a first facing surface, the first facing surface comprising a plurality of branch pathways formed as a recess within the first facing surface. The valve system further includes a second housing portion having a second facing surface, the second facing surface comprising a plurality of branch pathways formed as a recess within the second facing surface. A disposable conduit is configured to be interposed between the first and second housing portions and disposed within the recess of the first facing surface and the recess of the second facing surface. The disposable conduit is thus sandwiched between the first and second facing surfaces. A plurality of pinch valve actuators are mounted on one or both of the first housing portion and the second housing portion, the plurality of pinch valve actuators configured to pinch the disposable conduit at selective branch pathways.

The invention relates to a valve (1), comprising a valve housing (4) and a closing body (3) arranged in the valve housing (4) in such a way that the closing body can be moved longitudinally, wherein at least one inlet channel (5) and at least one outlet channel (6) are arranged in the valve housing (4). The closing body (3) interacts with a valve seat (8) formed on the valve housing (4) by means of the longitudinal motion of the closing body and thereby opens and closes at least one hydraulic connection between the at least one inlet channel (5) and the at least one outlet channel (6). The closing body (3) can be driven by means of a metal-bellows/piston unit (2), wherein the metal-bellows/piston unit (2) has a variable-length metal bellows (20) and a variable-volume working chamber (23) and wherein the metal bellows (20) bounds the working chamber (23) in a sealing manner.

An encapsulated valve system includes a first housing portion having a first facing surface, the first facing surface comprising a plurality of branch pathways formed as a recess within the first facing surface. The valve system further includes a second housing portion having a second facing surface, the second facing surface comprising a plurality of branch pathways formed as a recess within the second facing surface. A disposable conduit is configured to be interposed between the first and second housing portions and disposed within the recess of the first facing surface and the recess of the second facing surface. The disposable conduit is thus sandwiched between the first and second facing surfaces. A plurality of pinch valve actuators are mounted on one or both of the first housing portion and the second housing portion, the plurality of pinch valve actuators configured to pinch the disposable conduit at selective branch pathways.

A pinch valve may use a spring force to close a collapsible tube at a pinch point, and may open with a cam mechanism, which may be controlled using an electric motor. The open and closed positions of the pinch valve may be stable without the use of continuing electrical energy, and electrical energy may be consumed during a change between positions. One arrangement may use multiple tubes in a circular arrangement with a cam that may operate one or more of the valves at a time. The cam mechanism may be driven by an electric motor.

A flow switch device includes a flow switch with four ports oriented at 90 degree intervals around a center of the flow switch. The flow switch is of a type that forms selectable flow passages between ports separated by 90 degrees and blocks flow between ports separated by 180 degrees in each of multiple selected positions. Two of the ports are connected to fixed flow passages and each of the fixed flow passages defines a flow path toward a remote port separated from each of the fixed flow passages by 180 degrees so that each of the fixed flow passages and a respective remote port are positioned in pairs on opposite sides of the flow switch.

An encapsulated valve system includes a first housing portion having a first facing surface, the first facing surface comprising a plurality of branch pathways formed as a recess within the first facing surface. The valve system further includes a second housing portion having a second facing surface, the second facing surface comprising a plurality of branch pathways formed as a recess within the second facing surface. A disposable conduit is configured to be interposed between the first and second housing portions and disposed within the recess of the first facing surface and the recess of the second facing surface. The disposable conduit is thus sandwiched between the first and second facing surfaces. A plurality of pinch valve actuators are mounted on one or both of the first housing portion and the second housing portion, the plurality of pinch valve actuators configured to pinch the disposable conduit at selective branch pathways.

An encapsulated valve system includes a first housing portion having a first facing surface, the first facing surface comprising a plurality of branch pathways formed as a recess within the first facing surface. The valve system further includes a second housing portion having a second facing surface, the second facing surface comprising a plurality of branch pathways formed as a recess within the second facing surface. A disposable conduit is configured to be interposed between the first and second housing portions and disposed within the recess of the first facing surface and the recess of the second facing surface. The disposable conduit is thus sandwiched between the first and second facing surfaces. A plurality of pinch valve actuators are mounted on one or both of the first housing portion and the second housing portion, the plurality of pinch valve actuators configured to pinch the disposable conduit at selective branch pathways.

A control valve includes a tube housing, a tube within the tube housing, and a clamp within the tube housing. The tube is disposed between a first portion of the tube housing and the clamp, and the clamp is movable between an open position and a closed position. The clamp in the open position is located away from the first portion of the tube housing, and the clamp in the first closed position is located adjacent to the first portion of the tube housing.