A fluidic device comprises a channel, a gate, and one or more additional elements. The channel is configured to transport a fluid from a source to a drain. The gate includes a chamber with an adjustable volume that affects fluid flow within the channel by displacing a wall of the channel toward an opposite wall of the channel based in part on fluid pressure within the chamber exceeding a threshold pressure. A high pressure state of the gate corresponds to a first chamber size and a first flow rate of the fluid. A low pressure state of the gate corresponds to a second chamber size that is smaller than the first chamber size and a second flow rate that is greater than the first flow rate. The additional elements are configured to reduce the threshold pressure past which the chamber decreases the cross-sectional area of the channel.

The present invention aims to provide a fluid handling device which can be manufactured more conveniently, can easily open and close a channel, and can be miniaturized. The fluid handling device of the present invention includes: a first channel; a second channel; and a valve disposed between the first channel and the second channel, in which the valve includes: a groove-shaped valve seat disposed in a board, and a flat plate-shaped flexible layer covering the groove-shaped valve seat, and the valve communicates between the first channel and the second channel when the flat plate-shaped flexible layer and a bottom of the groove-shaped valve seat are spaced apart from each other, and blocks communication between the first channel and the second channel when the flat plate-shaped flexible layer and an inner wall of the groove-shaped valve seat are in contact with each other.

A fluid handling device includes a first channel, a second channel, and a valve disposed at a connection part between the first channel and the second channel. The valve include a partition wall disposed between the first channel and the second channel, and a diaphragm disposed so as to face the partition wall, a portion of the first channel, and a portion of the second channel. The diaphragm is configured in such a way that when no pressure is applied to the diaphragm, a gap, which serves as a third channel that allows the first channel and the second channel to communicate with each other, is formed between the diaphragm and the partition wall. In plan view, the length of the diaphragm in the extending direction of the third channel is longer than the length of the diaphragm in the direction orthogonal to the extending direction.

A fluid handling device, comprising: a substrate including a first channel, a second channel and a partition wall formed between the first channel and the second channel; a film including a diaphragm, the film being disposed on the substrate so that the diaphragm faces the partition wall; and a sliding member slidable on the film while contacting with the film, the sliding member including a protrusion formed on an underside thereof, and the sliding member being disposed on the film with the underside facing the film, wherein: the sliding member is capable of switching between a first state and a second state by sliding on the film, wherein the protrusion is positioned so as not to face the partition wall with the diaphragm therebetween in the first state, and the protrusion is positioned so as to face the partition wall with the diaphragm therebetween in the second state.

A fluid control apparatus includes a piezoelectric pump and valve. The valve includes a second valve housing, second seal member, diaphragm, first seal member, and first valve housing and has a structure in which they are laminated in sequence. The first valve housing includes a second vent and third vent, has a valve seat, and includes six cavities. The second valve housing has a first vent and first vent and includes a valve seat and six first protrusions. The second valve housing further includes six second protrusions nearer the outer edges than the six first protrusions, as seen in the x-axis direction in plan view.

A micro-pneumatic control unit comprising a plurality of control channels for generating the control pressures in a pneumatically actuated multi-channel coating head for coating components with a coating agent, a control channel being characterized by a valve element comprising a valve bore in a valve plate and a diaphragm layer which is below the valve plate and is configured as a diaphragm closing element in the region of the valve bore, the shape of which diaphragm closing element defined by recesses positioned laterally with respect to the valve bore, by a micro-actuator having a plunger that actuates the diaphragm closing element through the valve bore such that the valve element opens, by a second micro-pneumatic element connected in series with the valve element, the control pressure developing and a cavity located at the connection node thereof, which cavity is connected to at least one pneumatically operated coating agent ejector, and by a pneumatic pressurization of the micro-pneumatic control unit, which is directed such that, with respect to the valve element, there is a pressure gradient from the diaphragm closing element to the valve bore in the valve plate.

A micro pump is disclosed and includes a fluid-converging plate, a valve membrane, a fluid-outlet plate and a pump core module. The fluid-converging plate includes an inner recess, a protruding portion and a fluid-converging aperture. The protruding portion is disposed at a center of the inner recess. The valve membrane includes a valve aperture. The protruding portion of the fluid-converging plate abuts against the valve aperture. A fluid-converging chamber is formed between the valve membrane and the fluid-converging plate. The fluid-outlet plate in a ring shape includes a fluid-outlet channel. The valve aperture is in fluid communication with the fluid-outlet channel. When the fluid is inhaled into the pump core module, the fluid flows to the fluid-converging chamber through the fluid-converging aperture and then pushes out the valve membrane to flow into the fluid-outlet channel of the fluid-outlet plate through the valve aperture. Thereby the fluid transportation is achieved.

A micro channel structure includes a substrate, a supporting layer, a valve layer, a second insulation layer, a vibration layer and a bonding-pad layer. A flow channel is formed on the substrate. A conductive part and a movable part are formed on the supporting layer and the valve layer, respectively. A first chamber is formed at the interior of a base part and communicates to the hollow aperture. A supporting part is formed on the second insulation layer. A second chamber is formed at the interior of the supporting layer and communicates to the first chamber through the hollow aperture. A suspension part is formed on the vibration layer. By providing driving power sources having different phases to the bonding-pad layer, the suspension part moves upwardly and downwardly, and a relative displacement is generated between the movable part and the conductive part, to achieve fluid transportation.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

The invention relates to a device for synthesising oligonucleotides, comprising: a reagent container receptacle (1) for holding a reagent container support (17) comprising multiple reagent containers (18); an exchangeable microfluid chip (10) comprising a synthesis chamber, fluid connectors and microfluid valves; a control device (5); fluid connecting means (2); wherein the device can be loaded with the microfluid chip (10) and the reagent container support (17) when in a loading position; a chip receptacle (3). To allow cost-effective and prompt synthesis even of small amounts of oligonucleotides, the invention provides for an actuator device (6) to be provided, with which the reagent container receptacle (1), the microfluid chip (10) and the fluid connecting means (2) can be brought from the loading position to an operating position, in which operating position the reagent container receptacle (1), the chip receptacle (3) and the fluid connecting means (2) are positioned relative to each other such that reagents can be conveyed out of the reagent containers (18) towards the synthesis chamber (14) depending on the valve position of the microfluid valves.