Disclosed is a solvent dispensing system that includes a plurality of air-operated double diaphragm pumps, which are adapted to couple to a plurality of solvent supply containers, and coupled to a plurality of dispensing nozzles, wherein each air-operated double diaphragm pump is powered by a separate air supply line carrying pressurized air, and is controlled by a separate air directional control valve. The solvent dispensing system further includes a sealing cap device for coupling a solvent container to a solvent supply line. The sealing cap device is adapted to form a seal around a solvent discharge opening in a solvent container. The sealing cap device has a check valve and breather combination and a fitting for coupling the solvent container to a solvent supply line. Also disclosed is a clamping system for pressing the sealing cap device around the solvent discharge opening in the solvent container.

Membranes are provided to be specially developed for use in chambers for artificial circulatory assistance which may be employed primarily in cardiovascular procedures, notably to produce arterial capacitance, to regulate blood pressure, to produce aortic counterpulsation and to pump blood. The membrane may have circular sections that may vary in size or not depending on the function to be performed and are interconnected so that the transition between one section and the other is smooth, regardless of the size of each section. Further, chambers and pumps may be used for cardiopulmonary bypass and a pumping system.

An electronically controlled diaphragm pump system includes a pump housing with a drive gas chamber, a fluid chamber separated by a diaphragm, gas pressure means for providing a drive gas pressure in response to a control signal, and gas under-pressure means connected to a gas outlet port for providing a gas outlet under-pressure or sucking of gas in response to a control signal. The pump system has a displacement sensor and control circuitry connected to the displacement sensor for determining the displacement or position of the diaphragm and adapted or supplying the control signals to the gas pressure means and the gas under-pressure means.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

An electronically controlled diaphragm pump system includes a pump housing with a drive gas chamber, a fluid chamber separated by a diaphragm, gas pressure means for providing a drive gas pressure in response to a control signal, and gas under-pressure means connected to a gas outlet port for providing a gas outlet under-pressure or sucking of gas in response to a control signal. The pump system has a displacement sensor and control circuitry connected to the displacement sensor for determining the displacement or position of the diaphragm and adapted or supplying the control signals to the gas pressure means and the gas under-pressure means.

A membrane-based piston pump (400) is used for pumping a liquid product. The pump is provided with a device (426) for maintaining a pre-defined hydraulic fluid volume in the pump. The device includes an axle element (440) and a bushing element (432). A method for pumping a liquid product in a pump may use the membrane-based piston pump. A homogenizer may include the membrane-based piston pump.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

An elongate air operated pump includes a pump chamber, a bladder inside the pump chamber, inlet and outlet valves to and from the chamber and an air control system. The air control system includes a control valve alternately communicating compressed air and exhaust to atmosphere to a venturi with a first end, a second end and a throat port. The first end of the venturi receives continuous compressed air. The second end receives the alternately communication of compressed air and exhaust to atmosphere from the control valve. The throat port of the venturi is in continuous communication with the bladder to pressurize and draw a vacuum on the bladder. The valves may be pneumatic pinch valves controlled by the control valve to cycle with the bladder or passive one-way pump valves.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

Disclosed is solvent dispensing system comprising a plurality of air-operated double diaphragm pumps, adapted to couple to a plurality of solvent supply containers, and coupled to a plurality of dispensing nozzles, wherein each air-operated double diaphragm pump is powered by a separate air supply line carrying pressurized air, and is controlled by a separate air directional control valve. The present invention also provides a means of coupling a solvent container to a solvent supply line, comprising a sealing cap device for forming a seal around a solvent discharge opening in a solvent container, said sealing cap device having a check valve and breather combination and a means for coupling the solvent container to a solvent supply line. Also disclosed is a clamping system for pressing the sealing cap device around the solvent discharge opening in the solvent container.