A method for increasing satiety from food via use of a nondigestible nonfibrous physical volumizer. Distention of the stomach reduces hunger and increases food satiety. The invention increases volume of the mass being ingested without increasing the caloric value of the ingested quantity. This is achieved by use of a volumizing substance that is not metabolized by the body. Polytetrafluoroethylene (PTFE) is one material that could be used as a meal-content volumizing substance.

Provided are glycosylated polymers that derive from carboxymethyl cellulose and may function as synthetic mucins. The carboxymethyl cellulose backbone of the polymers provide structures amenable to glycosylation by amidation of the carboxyl groups with glycosylamine moieties. The polymers can inhibit microbial virulence and may be useful in a variety of applications, such as treating microbial infections, preventing biofilm formation, and improving gastrointestinal health. Thus, provided are compositions (e.g., pharmaceutical, prebiotic, nutraceutical, food product) comprising the polymers, lubricants comprising the polymers, coatings comprising the polymers, methods of inhibiting microbial virulence, methods of inhibiting and/or preventing biofilm formation, methods of treating and/or preventing infection (e.g., bacterial, protozoan, or fungal infection). Also provided are methods of preparing the polymers described herein.

Provided are glycosylated polymers that derive from carboxymethyl cellulose and may function as synthetic mucins. The carboxymethyl cellulose backbone of the polymers provide structures amenable to glycosylation by amidation of the carboxyl groups with glycosylamine moieties. The polymers can inhibit microbial virulence and may be useful in a variety of applications, such as treating microbial infections, preventing biofilm formation, and improving gastrointestinal health. Thus, provided are compositions (e.g., pharmaceutical, prebiotic, nutraceutical, food product) comprising the polymers, lubricants comprising the polymers, coatings comprising the polymers, methods of inhibiting microbial virulence, methods of inhibiting and/or preventing biofilm formation, methods of treating and/or preventing infection (e.g., bacterial, protozoan, or fungal infection). Also provided are methods of preparing the polymers described herein.

Provided herein is a novel composition for oral administration and delivery of Noble gas, such as xenon or argon. Methods of treating and preventing neuronal or cardiovascular damage with such compositions are also provided.

Provided herein is a novel composition for oral administration and delivery of Noble gas, such as xenon or argon. Methods of treating and preventing neuronal or cardiovascular damage with such compositions are also provided.

A method for increasing satiety from food via use of a nondigestible nonfibrous physical volumizer. Distention of the stomach reduces hunger and increases food satiety. The invention increases volume of the mass being ingested without increasing the caloric value of the ingested quantity. This is achieved by use of a volumizing substance that is not metabolized by the body. Polytetrafluoroethylene (PTFE) is one material that could be used as a meal-content volumizing substance.

A method for increasing satiety from food via use of a nondigestible nonfibrous physical volumizer. Distention of the stomach reduces hunger and increases food satiety. The invention increases volume of the mass being ingested without increasing the caloric value of the ingested quantity. This is achieved by use of a volumizing substance that is not metabolized by the body. Polytetrafluoroethylene (PTFE) is one material that could be used as a meal-content volumizing substance.

Appetite suppression and weight management achieved through pre-meal ingestion of temporary gastric bulking agents in the form of superabsorbent polymer hydrogels (SAPHs) selected from among a group consisting of crosslinked polycarboxylic acid moieties is described. The preferred compositions and manufacturing methods of ultrapure preparations of ingestible forms; as well as the preferred methods of use, dosage and administration; distribution and delivery of SAPH materials are also described.

Appetite suppression and weight management achieved through pre-meal ingestion of temporary gastric bulking agents in the form of superabsorbent polymer hydrogels (SAPHs) selected from among a group consisting of crosslinked polycarboxylic acid moieties is described. The preferred compositions and manufacturing methods of ultrapure preparations of ingestible forms; as well as the preferred methods of use, dosage and administration; distribution and delivery of SAPH materials are also described.

The invention relates to compositions and formulations for managing weight in obese persons and individuals who wish to maintain their weight in a desired value regardless of their lifestyle habits or food preferences. The compositions comprise polymeric compounds that when administered as described herein form an intestinal overlay in situ which modulates the absorption of nutrients in the intestines for certain periods of time.