An encapsulated valve system includes a first housing portion having a first facing surface, the first facing surface comprising a plurality of branch pathways formed as a recess within the first facing surface. The valve system further includes a second housing portion having a second facing surface, the second facing surface comprising a plurality of branch pathways formed as a recess within the second facing surface. A disposable conduit is configured to be interposed between the first and second housing portions and disposed within the recess of the first facing surface and the recess of the second facing surface. The disposable conduit is thus sandwiched between the first and second facing surfaces. A plurality of pinch valve actuators are mounted on one or both of the first housing portion and the second housing portion, the plurality of pinch valve actuators configured to pinch the disposable conduit at selective branch pathways.

A clamp for selectively compressing a portion of tubing, such as an extension leg of a PICC or other catheter, is disclosed. The clamp is able to be opened or closed with a thumb and finger of a single hand of a user and is slidably attached to the tubing so as to enable its placement as desired along the tube. In one embodiment, the tubing clamp comprises a body including first and second body portions hingedly connected to one another in a clamshell configuration, a latch for releasably latching the first and second body portions together, and at least two tube compression members. The tube compression members cooperate to compress and occlude a portion of tubing passing through the tubing clamp when the first and second body portions are latched to one another.

Flow controllers for intravenous (IV) tubing are provided. A flow controller may include a first structural member comprising a first outer surface and a first inner surface disposed at an angle to the first outer surface, a second structural member comprising a second outer surface parallel to the first outer surface and a second continuous inner surface parallel to the first inner surface, and a third structural member disposed on one of the first or second structural member and having a friction-reducing surface for at least a portion of a cavity disposed between the first and second structural members. The first structural member is linearly slidable along a length of the IV tubing disposed in the cavity to compress a portion of the IV tubing to control flow of a medical fluid through the IV tubing. Other flow controllers and IV sets that include a flow controller are also provided.