A sodium-cooled nuclear reactor includes at least one electromagnetic pump assembly and a backflow reduction pipe. The backflow reduction pipe may include an inlet, an outlet, at least one tubular section having a first length and a first diameter, and at least one fluid diode section between the inlet and the outlet.

A single-layer valve is provided. The valve comprises a microfluidic pathway at least partially defined by a flexible membrane which is configured to deform when subjected to an actuation torque, and a discontinuity bounded by a first surface. The length of the discontinuity is constant across the full width of the first surface. The valve is configured such that the actuation torque on the membrane is larger in a first direction than a second direction substantially opposite to the first direction.

The invention relates to a valve, in particular for a device for administering a liquid medicament, with a valve body (1) which has an interior (2) for receiving a liquid (20), wherein the valve body (1) has a liquid inlet (3) and an opposite liquid outlet (4) which both open into the interior (2), wherein the interior (2) accommodates a large number of micro channels (5) which extend in connection direction (x) between the liquid inlet (3) and the liquid outlet (4). A corresponding device for administering a liquid medicament is also described.

A fluid transportation device includes a valve cover, a valve body, a valve membrane and a valve chamber seat. The valve cover has two openings. The valve body includes an inlet passage and an outlet passage. The valve membrane is arranged between the valve body and the valve chamber seat, having two valve plates respectively close an inlet valve channel and an outlet valve channel of the valve chamber seat. The valve chamber seat forms a pressure chamber which is sealed and covered by an actuator. The valve cover is sleeved on the valve body and tightly fitted to the inner wall of an outer sleeve to assemble the device, in which a first gasket is disposed between the valve body and the valve membrane, and a second gasket is disposed between the valve membrane and the valve chamber, by which sealing effect is improved and backflow is prevented.

The present application discloses a micro-valve comprising: a first valve body and a second valve body, at least one of the first and second valve bodies defining a valve chamber and a valve seat, the first valve body having a liquid outlet and the second valve body having a liquid inlet; a valve plug disposed and movable within the valve chamber; and an elastic member disposed within the valve chamber and positioned closer to the liquid inlet than the valve plug. The elastic member has a liquid-inflow position and a liquid-outflow position, and in the liquid-inflow position, the elastic member enables liquid to flow from the liquid inlet through the elastic member to the liquid outlet, in the liquid-outflow position, the valve plug compresses the elastic member, such that the compressed elastic member seals the valve seat, or the compressed elastic member together with the valve plug seals the valve seat, so as to prevent liquid from flowing back from the liquid outlet to the liquid inlet through the valve seat.

A sodium-cooled nuclear reactor includes at least one electromagnetic pump assembly and a backflow reduction pipe. The backflow reduction pipe may include an inlet, an outlet, at least one tubular section having a first length and a first diameter, and at least one fluid diode section between the inlet and the outlet.

An implantable body fluid drainage system includes a metering shunt having a housing with an internal chamber. A movable barrier divides the chamber into a first section and a second section, and the barrier can be displaced by a differential pressure. A first powered inlet valve providing a fill path to the first section of the chamber, and a first powered drain valve providing a drain path from the first section of the chamber. A CSF inlet conduit connects a CSF space to the first powered inlet valve. A CSF outlet conduit connects the first powered outlet valve to a discharge location. A controller opens the first powered inlet valve and close the first powered drain valve to fill the first section to a volume defined by the barrier and chamber geometry and closes the first powered inlet valve and opens the first powered drain valve to discharge the filled volume from the first section through the outlet conduit.

A method for determining a treatment agent and dosage level for a biologic material includes the biologic sample is pumped into each of a first plurality of parallel pathways from the first reservoir using a micro-pump. A separate treatment agent of the plurality of treatment agents is applied within each of the first plurality of parallel pathways. The treatment agent providing a best treatment efficacy for the predetermined biologic material within the biologic sample is determined. A second portion of the biologic sample is pumped into a selected second parallel pathway associated with the determined treatment agent of a second plurality of parallel pathways from the first reservoir using a second micro-pump. The determined treatment agent at a plurality of different dosage levels is applied within the selected second parallel pathway. A dosage level of the plurality of different dosage levels of the determined treatment agent is determined.

This invention describes a design for a multiwell plate that contains integrated pumps that are used to stir each well of the plate. The device employs microfluidic logic technology to drive each peristaltic pump. This enables the plates to run autonomously, requiring only a static vacuum supply for power. The devices are entirely constructed out of low-cost polymers, with no electronics, and yet contains simple digital logic circuits to control the pumps. A stack of these plates may be run continuously in a standard cell culture incubator, allowing high-throughput culture of organoids.

An integrated system for processing and preparing samples for analysis may include a microfluidic device including a plurality of parallel channel networks for partitioning the samples including various fluids, and connected to a plurality of inlet and outlet reservoirs, at least a portion of the fluids comprising reagents, a holder including a closeable lid hingedly coupled thereto, in which in a closed configuration, the lid secures the microfluidic device in the holder, and in an open configuration, the lid is a stand orienting the microfluidic device at a desired angle to facilitate recovery of partitions or droplets from the partitioned samples generated within the microfluidic device, and an instrument configured to receive the holder and apply a pressure differential between the plurality of inlet and outlet reservoirs to drive fluid movement within the channel networks.