The present invention provides a means of raising the solubility of even a slightly soluble amino acid, without needing an expensive peptide or varying the pH. The present invention also provides a composition containing at least two amino acids which are formed into a co-amorphous structure.

Administering an amino acid-containing composition, containing the following amino acids (1)-(9), wherein the molar content ratio of each amino acid to the total content of the amino acids (1)-(9) falls within the following numerical ranges: (1) leucine 35-66%; (2) isoleucine 5.0-15%; (3) valine 5.0-15%; (4) threonine 7.0-14%; (5) lysine 8.0-16%; (6) methionine 2.0-10%; (7) histidine 0.1-3.5%; (8) phenylalanine 2.5-8.0%; and (9) tryptophan 0.1-2.0%,
is effective for enhancing recovery from muscle fatigue.

Administering an amino acid-containing composition, containing the following amino acids (1)-(9), wherein the molar content ratio of each amino acid to the total content of the amino acids (1)-(9) falls within the following numerical ranges: (1) leucine 35-66%; (2) isoleucine 5.0-15%; (3) valine 5.0-15%; (4) threonine 7.0-14%; (5) lysine 8.0-16%; (6) methionine 2.0-10%; (7) histidine 0.1-3.5%; (8) phenylalanine 2.5-8.0%; and (9) tryptophan 0.1-2.0%,
is effective for enhancing recovery from muscle fatigue.

A method and composition for preserving muscle mass and function by increasing muscle protein synthesis and/or decreasing muscle protein degradation in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at least two of an essential amino acid, an amino acid derivative, and a nitrogenous organic acid. In a particular embodiment, the protein building composition comprises leucine, L-carnitine, and creatine. The protein building composition can decrease TNF-α and increase mTOR expression in muscle.

A method and composition for preserving muscle mass and function by increasing muscle protein synthesis and/or decreasing muscle protein degradation in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at least two of an essential amino acid, an amino acid derivative, and a nitrogenous organic acid. In a particular embodiment, the protein building composition comprises leucine, L-carnitine, and creatine. The protein building composition can decrease TNF-α and increase mTOR expression in muscle.

Nutritional formulation suitable to manage the diet for phenylketonuria, which comprises glycomacropeptide (GMP) as the primary source of proteins and additional complementary essential amino acids, to complete the required protein profile, supplied in a mixture comprising arginine, cystine, histidine, tryptophan, tyrosine and leucine.

Nutritional formulation suitable to manage the diet for phenylketonuria, which comprises glycomacropeptide (GMP) as the primary source of proteins and additional complementary essential amino acids, to complete the required protein profile, supplied in a mixture comprising arginine, cystine, histidine, tryptophan, tyrosine and leucine.

This invention covers protein essential amino acids formulations as dietary supplements, nutritional formulations and foods that provide balanced and adequate levels of essential amino acid compositions to meet the recommended nutritional requirements for humans of different age groups and special need groups.

This invention covers protein essential amino acids formulations as dietary supplements, nutritional formulations and foods that provide balanced and adequate levels of essential amino acid compositions to meet the recommended nutritional requirements for humans of different age groups and special need groups.

Compositions containing one or more kinds of essential amino acids other than leucine and not less than 35 mol % of leucine, relative to the total content of essential amino acids, s are useful for preventing or improving dementia or a depressive state, in particular, a depressive state caused by stress, have high safety, and can be continuously ingested or administered.