The present invention generally relates to compositions and methods for supporting exercise performance or activities of daily living. The compositions described herein are pharmaceutical or nutritional compositions suitable for enhancing exercise performance. The compositions are based on a specially formulated mixture of essential amino acids (EAAs) with additional components. The compositions target support of muscle protein synthesis and reduction of muscle breakdown during exercise, increasing muscle blood flow during exercise, decreasing the perception of fatigue by supporting optimal availability of neurotransmitter precursors, providing energy for rapids bursts of exertion during exercise, and maintaining adequate electrolyte balance during exercise.

The present invention generally relates to compositions and methods for supporting exercise performance or activities of daily living. The compositions described herein are pharmaceutical or nutritional compositions suitable for enhancing exercise performance. The compositions are based on a specially formulated mixture of essential amino acids (EAAs) with additional components. The compositions target support of muscle protein synthesis and reduction of muscle breakdown during exercise, increasing muscle blood flow during exercise, decreasing the perception of fatigue by supporting optimal availability of neurotransmitter precursors, providing energy for rapids bursts of exertion during exercise, and maintaining adequate electrolyte balance during exercise.

Administering an amino acid-containing composition, containing the following amino acids (1)-(9), wherein the molar content ratio of each amino acid to the total content of the amino acids (1)-(9) falls within the following numerical ranges: (1) leucine 35-66%; (2) isoleucine 5.0-15%; (3) valine 5.0-15%; (4) threonine 7.0-14%; (5) lysine 8.0-16%; (6) methionine 2.0-10%; (7) histidine 0.1-3.5%; (8) phenylalanine 2.5-8.0%; and (9) tryptophan 0.1-2.0%,
is effective for enhancing recovery from muscle fatigue.

Administering an amino acid-containing composition, containing the following amino acids (1)-(9), wherein the molar content ratio of each amino acid to the total content of the amino acids (1)-(9) falls within the following numerical ranges: (1) leucine 35-66%; (2) isoleucine 5.0-15%; (3) valine 5.0-15%; (4) threonine 7.0-14%; (5) lysine 8.0-16%; (6) methionine 2.0-10%; (7) histidine 0.1-3.5%; (8) phenylalanine 2.5-8.0%; and (9) tryptophan 0.1-2.0%,
is effective for enhancing recovery from muscle fatigue.

This invention covers protein essential amino acids formulations as dietary supplements, nutritional formulations and foods that provide balanced and adequate levels of essential amino acid compositions to meet the recommended nutritional requirements for humans of different age groups and special need groups.

This invention covers protein essential amino acids formulations as dietary supplements, nutritional formulations and foods that provide balanced and adequate levels of essential amino acid compositions to meet the recommended nutritional requirements for humans of different age groups and special need groups.

Compositions containing one or more kinds of essential amino acids other than leucine and not less than 35 mol % of leucine, relative to the total content of essential amino acids, s are useful for preventing or improving dementia or a depressive state, in particular, a depressive state caused by stress, have high safety, and can be continuously ingested or administered.

Amino acid formulations for cardiac vitality. The formulations comprise a mixture of a plurality of amino acids, wherein the mixture comprises at least one amino acid selected from the group consisting of serine, threonine, histidine, and/or proline, and optionally arginine Methods of enhancing smooth muscle cell vitality, stabilizing cardiac health, and decreasing oxidative stress and inflammation are also described.

Amino acid formulations for cardiac vitality. The formulations comprise a mixture of a plurality of amino acids, wherein the mixture comprises at least one amino acid selected from the group consisting of serine, threonine, histidine, and/or proline, and optionally arginine Methods of enhancing smooth muscle cell vitality, stabilizing cardiac health, and decreasing oxidative stress and inflammation are also described.

The invention relates to a recombinant, L-amino acid-secreting microorganism of the Enterobacteriaceae family, comprising an DNA fragment having promoter activity that is functionally linked to a polynucleotide coding for a membrane protein, characterized in that the DNA fragment having promoter activity comprises the SEQ ID NO: 8.