The present invention provides compositions and methods for improving the quality of life for a subject, particularly a child, diagnosed with autism spectrum disorder (ASD). In preferred embodiments, a supplement composition comprising natural or naturally-derived ingredients is delivered to a subject in the form of a chocolate bar or other candy alongside administration of an antiviral medication. Advantageously, the composition and methods can improve the immune health of the subject, along with other signs and symptoms associated with ASD, infections and other immunocompromising conditions.

The present invention provides compositions and methods for improving the quality of life for a subject, particularly a child, diagnosed with autism spectrum disorder (ASD). In preferred embodiments, a supplement composition comprising natural or naturally-derived ingredients is delivered to a subject in the form of a chocolate bar or other candy alongside administration of an antiviral medication. Advantageously, the composition and methods can improve the immune health of the subject, along with other signs and symptoms associated with ASD, infections and other immunocompromising conditions.

A method of reversibly increasing intestinal epithelium permeability is provided. A plant polyphenol composition, such as a pelargonidin-containing composition is enterically-administered, e.g., with a high molecular weight therapeutic agent, such as insulin, such that therapeutic agents having high molecular weights can be delivered enterically. An oral dosage form for enteric delivery of high molecular weight therapeutic agents also is provided.

A dietary supplement composition, which may be used for treating neurological and developmental disorders in human subjects, includes trans-resveratrol, ginkgo biloba, Coenzyme Q10, and natural flavonoids blend, in which a content of the trans-resveratrol is about 250 mg; a content of the ginkgo biloba is about 120 mg; a content of the Coenzyme Q10 is about 100 mg; and a content of the natural flavonoids blend is about 256 mg. The natural flavonoids blend may include quercetin, fisetin derived from strawberries; and anthocyanidin and anthocyanin derived from European blueberry extracts. The dietary supplement composition according another aspect includes at least three of trans-resveratrol, ginkgo biloba, Coenzyme Q10, and natural flavonoids blend. The dietary supplement compositions further includes zinc gluconate, cyanocbalamin and taurine. Such dietary supplement compositions are effective and efficient for treating subjects having neurological disorders including autism spectrum disorders, and Alzheimer's disease.

The present invention relates to a composition including an anthocyanin-fucoidan complex formed by ionic bond between anthocyanin and fucoidan as an active ingredient, and more particularly, it is confirmed that the anthocyanin-fucoidan complex in which anion of the fucoidan, which is a natural extract having high biocompatibility and biodegradability, is ionically bonded with a cation of the anthocyanin improves the stability and the solubility of the anthocyanin even in acidic conditions in vivo, thereby increasing the immune activity in vivo and therefore it is intended to provide the anthocyanin-fucoidan complex as an immune enhancer, an immune-cancer agent and an anticancer adjuvant composition for alleviating side effects of anti-cancer agents.

The present invention relates to a composition including an anthocyanin-fucoidan complex formed by ionic bond between anthocyanin and fucoidan as an active ingredient, and more particularly, it is confirmed that the anthocyanin-fucoidan complex in which anion of the fucoidan, which is a natural extract having high biocompatibility and biodegradability, is ionically bonded with a cation of the anthocyanin improves the stability and the solubility of the anthocyanin even in acidic conditions in vivo, thereby increasing the immune activity in vivo and therefore it is intended to provide the anthocyanin-fucoidan complex as an immune enhancer, an immune-cancer agent and an anticancer adjuvant composition for alleviating side effects of anti-cancer agents.

An object of the present invention is to provide a technique of suppressing precipitation of an anthocyanin pigment in a range other than the highly acidic range. The present invention provides an anthocyanin pigment preparation, comprising: an anthocyanin pigment; and an emulsifier, wherein the pH when the anthocyanin pigment preparation is diluted with water or dissolved in water so that a color value becomes 10 is more than 3.

An object of the present invention is to provide a technique of suppressing precipitation of an anthocyanin pigment in a range other than the highly acidic range. The present invention provides an anthocyanin pigment preparation, comprising: an anthocyanin pigment; and an emulsifier, wherein the pH when the anthocyanin pigment preparation is diluted with water or dissolved in water so that a color value becomes 10 is more than 3.

Nutritional supplement compositions for improving cardiovascular efficiency are disclosed. A nutritional supplement composition can include astaxanthin derived from Haematococcus pluvialis Extract blended with carrier oils and antioxidants. Related processes are also disclosed.

Composition having a blue color including a buffer, an anthocyanin, and a divalent ion source. The composition may comprise an anthocyanin and a divalent ion source, wherein the average variation of E*.sub.ab of the composition is less than 30% of the average variation of E*.sub.ab of a control composition after exposure of the composition and the control composition to a 400 to 765 W/m.sup.2 light source for a period of time. The composition may comprise an anthocyanin and a divalent ion source, wherein the composition exhibits a less than 20% change in the area beneath the reflectance colorimeter spectral curve of the composition from 430 nm to 530 nm measured over a period of time. In another aspect, a method of stabilizing a blue colorant is provided. The method may comprise combining a buffer, an anthocyanin, and a divalent ion source.