Patent classifications
G01N1/28
Method for manufacturing sample for thin film property measurement and analysis, and sample manufactured thereby
The present invention relates to a method for manufacturing a sample for thin film property measurement and analysis, and a sample manufactured thereby and, more specifically, to: a method for manufacturing a sample capable of measuring or analyzing various properties in one sample; and a sample manufactured thereby.
Biopsy sample manipulation and imaging system and methods for use
An example fluidic device includes an elastic tube, a first actuator coupled to an outer surface of the elastic tube between a first end and a second end of the elastic tube, and a second actuator coupled to the outer surface of the elastic tube between the first actuator and the second end of the elastic tube. The first actuator and the second actuator are configured to move apart from one another to transition a portion of the elastic tube positioned between the first actuator and the second actuator from a first condition to a second condition. A diameter of the elastic tube is greater in the first condition than in the second condition. The fluidic device also includes one or more rotatable components coupled to the first actuator and the second actuator which are configured to rotate the portion of the elastic tube positioned between the first actuator and the second actuator.
Quantitative detection of non-fluorine anti-soil using a fluorescent trace indicator
A method for quantitatively and indirectly measuring non-fluorine anti-soil chemistry in carpet applications, is based on a known amount of FI trace to be added along with anti-soil chemistry in formulation prior to application to a carpet surface. The anti-soil chemistry with the trace amount of FI is then applied to the carpet through a topical foam or spray applicator during a precoating process. After completion of the precoat process, a carpet sample is collected, carpet face fiber is shaved, and FI is extracted using water. The extracted water solution is used to measure the fluorescence intensity (in counts per second or “CPS”) using a Fluorimeter.
Quantitative detection of non-fluorine anti-soil using a fluorescent trace indicator
A method for quantitatively and indirectly measuring non-fluorine anti-soil chemistry in carpet applications, is based on a known amount of FI trace to be added along with anti-soil chemistry in formulation prior to application to a carpet surface. The anti-soil chemistry with the trace amount of FI is then applied to the carpet through a topical foam or spray applicator during a precoating process. After completion of the precoat process, a carpet sample is collected, carpet face fiber is shaved, and FI is extracted using water. The extracted water solution is used to measure the fluorescence intensity (in counts per second or “CPS”) using a Fluorimeter.
METHOD FOR EXTRACTING NUCLEI OR WHOLE CELLS FROM FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUES
The subject matter disclosed herein is generally directed to isolating single cells and nuclei from tissue samples for use in the analysis of single cells from archived biological samples. The subject matter disclosed herein is directed to isolating single cells and nuclei from formalin-fixed paraffin-embedded (FFPE) tissues. The subject matter disclosed herein is also directed to isolating single nuclei that preserve ribosomes or ribosomes and rough ER from frozen tissues. The subject matter disclosed herein is also directed to therapeutic targets, diagnostic targets and methods of screening for modulating agents.
DETECTION METHOD FOR DETERMINING CONTENT OF CHLORINE IONS IN MARINE SAND
The present invention relates to a detection method for determining chloride ions content in sea sand, which is performed in the steps as follows: drying sea sand to a constant weight, adding the dried sea sand to boiling deionized water, and fully stirring, standing and filtering the deionized water to obtain washed sea sand and a washed filtrate; then grinding the washed sea sand into powder, adding the powder into deionized water, fully stirring and filtering the deionized water to obtain a powder filtrate; next, taking half of the washed filtrate and half of the powder filtrate, mixing and stirring the two to prepare a mixed filtrate; and measuring the chloride ions content in each of the washed filtrate, the powder filtrate and the mixed filtrate by using a silver nitrate titration method; finally, analyzing and correcting detection results to obtain the chloride ions content in the sea sand. The present invention promotes the release of the chloride ions in the tight-wrapping surface films and fissures of the sea sand to a great extent, providing a scientific guarantee for the authenticity of the detection results on the chloride ions content in the sea sand; and realizes the quick dissolution of the chloride ions, thereby greatly reducing the detection time and significantly increasing the accuracy of the detection results.
DEVICE FOR THE FRAGMENTATION OF TISSUES WITHIN A SEALED STERILE ENVIRONMENT WITH AN ASEPTIC PROCEDURE AND METHOD THEREOF
The invention relates to a device and the operating method therefor, for the fragmentation of a biological material within in a sealed sterile environment with an aseptic procedure.
METHOD FOR PREPARING CRYSTAL STRUCTURAL ANALYSIS SAMPLE FOR STRUCTURAL ANALYSIS OF NUCLEOPHILIC GROUP-CONTAINING COMPOUNDS BY CRYSTALLINE SPONGE METHOD
An object of the present invention is to provide a method of preparing a sample for crystallographic analysis used for structure determination of a compound having a nucleophilic group based on the crystalline sponge method. The present invention provides a method of preparing a sample for crystallographic analysis used for structure determination of a compound having a nucleophilic group based on the crystalline sponge method, the method including the steps: (A) derivatizing the nucleophilic group of the compound, and (B) soaking the derivatized compound into a crystalline sponge. The method of the invention allows the structure (particularly, absolute configuration) of a compound which is not amenable to structural analysis based on the crystalline sponge method to be quickly and precisely determined by a simple procedure.
Systems and methods for automated preparation of biological specimens
An automated system for processing a sample contained in a liquid sample container includes an automated tool head configured to rotate about a first axis, and to translate along a second axis different than the first axis, an analytic element positioner having an analytic element holder configured to releasably grip an analytic element, and a specimen transfer device carried by the tool head, wherein the tool head is configured to automatically position a working end of the specimen transfer device to obtain a specimen from a sample container held in the sample container holder, and to transfer the obtained specimen to an analytic element held by the analytic element holder, respectively, through one or both of rotation of the tool head about the first axis and translation of the tool head along the second axis.
Photoreactive ligands and uses thereof
Disclosed herein are methods for identifying proteins as targets for interaction with a small molecule ligand. Also disclosed herein are small molecule ligands and compositions for use in profiling druggable proteins.