A system for electronically and optically monitoring biological samples, the system including: a multi-well plate having a plurality of wells configured to receive a plurality of biological samples, each of the wells having a set of electrodes and a transparent window on a bottom surface of the well that is free of electrodes; an illumination module configured to illuminate the wells; a cradle configured to receive the multi-well plate, the cradle having an opening on the bottom that exposes the transparent windows of the wells; and an optical imaging module movable across different wells of a same multi-well plate to capture images through the windows.

A system and method for sorting sperm is provided. The system includes a housing and a microfluidic system supported by the housing. The system also includes an inlet providing access to the microfluidic system to deliver sperm to the microfluidic system and an outlet providing access to the microfluidic system to harvest sorted sperm from the microfluidic system. The microfluidic system provides a flow path for sperm from the inlet to the outlet and includes at least one channel extending from the inlet to the outlet to allow sperm delivered to the microfluidic system through the inlet to progress along the flow path toward the outlet. The microfluidic system also includes a filter including a first plurality of micropores arranged in the flow path between the inlet and the outlet to cause sperm traveling along the flow path to move against through the filter and gravity to reach the outlet.

In the present invention, information is analyzed, the positional relationship of cells/microbes in the optical axis direction is detected, and motility of cells/microbes is evaluated even in an out-of-focus view from an image obtained by a single image capture in an observation view of the cells/microbes. The present invention is provided with an optical system used to measure microparticles present in a sample liquid in a sample container, a drive mechanism for driving the sample container and/or a portion of the optical system in order to three-dimensionally search a bottom surface of the sample container, a control unit for controlling the optical system or the drive mechanism, an image processing unit for dividing an image of microparticles in the sample container at a first time and a second time into an in-focus region and an out-of-focus region and acquiring information relating to the microparticles, and a display unit for displaying the information relating to the microparticles as information representing a temporal change between the first time and the second time.

A search device updates positions and momentums of a plurality of virtual particles, for each unit time from an initial time to an end time. The search device, for each unit time, calculates, for each of the particles, a position at a target time of a corresponding particle, calculates, for each of a plurality of nodes, a first accumulative value by cumulatively adding positions at the target time of two or more particles corresponding to outgoing two or more directed edges, calculates, for each of the nodes, a second accumulative value by cumulatively adding positions at the target time of two or more particles corresponding to incoming two or more directed edges, and calculates, for each of the particles, a momentum at the target time of a corresponding particle based on the first accumulative value and the second accumulative value.

The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.

In one aspect, a system for controlling the operation of an agricultural implement may include a ground-engaging tool configured to engage soil within a field such that the tool creates a field material cloud aft of the tool as the implement is moved across the field. Furthermore, the system may include an imaging device configured to capture image data associated with the field material cloud created by the ground-engaging tool. Moreover, a controller of the disclosed system may be configured to identify a plurality of field material units within the field material cloud based on the image data captured by the imaging device. Additionally, the controller may be configured to determine a characteristic associated with the identified plurality of field material units.

A system that monitors particle motion behavior for point-of-care diagnostics is described. The system can include a sample testing unit configured to house a sample. The sample testing unit can include a plurality of motor structures configured for self-propulsion based on a presence or an absence of a target analyte in the sample and a plurality of beads configured to experience a motion behavior based on the self-propulsion of the plurality of motor structures. Each of the plurality of motor structures can include a catalytic motor-like micro/nanoparticle; and an attached functional material specific for the target analyte attached to the catalytic motor-like particle. The optical recording unit can include an optical arrangement configured to detect the motion behavior of the beads in the sample testing unit. The motion behavior can be indicative of the presence or the absence of the target analyte.

A method for determining the relative viability of sterilized male fruit flies, focusing on examination of the male fruit fly teste or testes to enable consideration of the spermatozoa extruding from the vas deferens of the teste. The evaluation may determine relative viability of the spermatozoa; spermatogenesis; activity or motility of the spermatozoa; or morphological or physiological sperm cell abnormalities. The spermatozoa activity may also be captured in still or moving images, to allow further consideration based on the images.

According to one embodiment, a processing system includes a chamber, a supplier, a detector, and a controller. The chamber is configured to store a processing object inside. The supplier is configured to supply a plurality of particles and a gas inside the chamber. The detector is configured to detect a state of air flow in a vicinity of the processing object. The controller is configured to control the supplier based on a detection value from the detector. The controller determines generation of a vortex based on data regarding a steady state of the air flow and the detection value from the detector, and controls the supplier to stop supply of the plurality of particles when the generation of the vortex is determined.

The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.