A particle sensing system which includes a plurality of micro-lenses which focus light from an unfocused or loosely focused light source onto a corresponding plurality of focus regions on a surface containing plasmonic structures. The absorption of light by the plasmonic structures in the focus regions results in heat dissipation in the plasmonic structures and consequently increases surface temperature in the focus regions. When an electrical field is applied to a sample fluid in contact with the surface, multiple electrothermal flows are induced in the fluid which rapidly transport suspended particles to the focus regions on the surface. The particles can then be captured and/or sensed.

Provided is an airborne microbial measurement apparatus and a method of measuring the same. The airborne microbial measurement apparatus includes a particle separation device comprising an introduction part for introducing air and a nozzle part disposed on one side of the introduction part, a microbial particle passage through which microbial particles in the air passing through an inner passage of the nozzle part flow, an air particle passage through which air particles in the air passing through an outer space of the nozzle part flow, a collection device communicating with the microbial particle passage, the collection device comprising a filter part onto which the microbial particles are collected, and a luminescence measurement device dispose on one side of the collection device to detect an amount or intensity of light emitted from the microbial particles collected onto the filter part.

The invention provides a sensor device which comprises an input flow channel (10) for receiving a gas flow with entrained matter to be sensed. A thermophoretic arrangement (14a, 14b) is used to induce a thermophoretic particle movement from a first, warmer, region (16) of the input flow channel to a second, cooler, region (18) of the input flow channel (10). A sensor (24) comprises a particle sensor component at or downstream of the first region (16) of the input flow channel (10). The invention provides the benefit of pre-filtering (e.g. removal of most suspended solids/liquids) without the need for a physical filter that can become blocked.

The present disclosure discloses a microfluidic chip, a system and a method for automatic separation and detection of circulating tumor cells. The microfluidic chip includes a density gradient centrifugation assembly, a cell capture assembly, and a reagent storage assembly. The density gradient centrifugation assembly is configured to carry out density gradient centrifugation on a whole blood sample to achieve separation and obtain a plasma layer, a monocyte layer, a Ficoll solution layer, and an erythrocyte and granulocyte layer. The cell capture assembly includes a capture channel, a capture inlet, and a capture outlet. The capture inlet and the capture outlet are in communication with the capture channel. An inner wall of the capture channel is provided with capture holes and negative-pressure capture chambers. Each capture hole is in communication with one negative-pressure capture chamber correspondingly. The reagent storage assembly is in communication with the capture inlet, and is configured for storing a staining solution and a wash solution.

A gas detecting device is disclosed and comprises a main body, a suspended particle sensing module and a gas sensing module, wherein the main body includes a first sensing area and a second sensing area. A suspended particle sensing module disposed within the first sensing area includes an irradiating mechanism, a first gas transporting actuator, a laser device and a light sensing device. The first gas transporting actuator transmits air to the first sensing area, the suspended particles in the air is irradiated by the laser beam emitted from the laser device to generate scattered light spots for the light sensing device to detect the suspended particles. The gas sensing module disposed within the second sensing area includes a gas sensor and a second gas transporting actuator. The second gas transporting actuator transmits air to the second sensing area, and the gas sensing device detects a gas composition contained in the air.

The present invention is to facilitate analysis of a plurality of analysis items. A cell analysis method for analyzing cells is provided in which data for analysis of cells contained in a sample are generated, and an artificial intelligence algorithm to be the input destination of the generated analysis data is selected from among a plurality of artificial intelligence algorithms, data indicating the properties of the cells are generated based on the analysis data via the artificial intelligence algorithm.

The purpose of the present invention is to provide a method for accurately predicting a cancer patient prognosis based on a count of desired cells for which expression of a leukocyte marker and an epithelial marker is hardly exhibited by detecting those cells. Provided is a method for diagnosing an overall survival prognosis for a patient suffering from cancer, the method including: a step of obtaining a concentrated solution containing desired cells by pre-treating a biological sample obtained from the patient; a step of optically detecting the concentrated cells; and a step of detecting the desired cells from the detected image, wherein an association is made with the overall survival prognosis diagnosis by counting the detected desired cells, and wherein the desired cells are cells confirmed by the existence of a cell nucleus and in which expression of a leukocyte marker and an epithelial marker is hardly exhibited.

A system and method for detecting particles in a fluidic medium using a microfluidic sensor is described. The system utilises microfluidic channels though which the fluidic medium is passed. On one section of the microfluidic channel, an array of non-flexible electrodes are coupled with uniform spacing therebetween. On the opposing section of the channel, a flexible electrode is coupled and all electrodes are connected to an electrical analyser which is used to generate an electrical field inside the microfluidic channel with the flexible electrode acting as ground. The flexible electrode is actuated by different means to narrow the width of the microfluidic in the section of interest and to capture the particle between the section, where sectional scans of the particles are obtained and electrical properties of the particle are measured, thereby detecting the particles in the fluidic medium.

According to an aspect of the present inventive concept there is provided a light excitation and collection device for a micro-fluidic system, comprising: a light source configured to generate excitation light; a plurality of excitation waveguides, each associated with a flow channel of the micro-fluidic system; wherein each excitation waveguide is configured to receive and redirect the excitation light towards the flow channel, such that the excitation light is elastically scattered by a sample in the flow channel forming forward and side scattered light; and wherein the light excitation and collection device further comprises: at least one forward scattered light collection point; and at least one side scattered light collection point; and wherein the forward scattered light collected for all excitation waveguides is detected by a first plurality of light sensitive areas and the side scattered light collected for all excitation waveguides is detected by a second plurality of light sensitive areas, the first and the second pluralities of light sensitive areas form different groups of light sensitive areas.

The disclosure describes a prism containing a microfluidic channel. By coupling bulk acoustic wave generators to opposing sides of the prism, a standing bulk acoustic wave field can be excited in the prism and in the microfluidic channel. Because the microfluidic channel is titled with respect to the nodes of the bulk acoustic wave field, the prism microfluidic channel device can be used to separate microparticles and biological cells by size, compressibility, density, shape, or mass distribution. This technology enables high throughput cell sorting for biotechnology applications such as cancer cell detection.